Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Mar 19, 2025; 15(3): 100909
Published online Mar 19, 2025. doi: 10.5498/wjp.v15.i3.100909
Relationship between weight-to-waist index and post-stroke depression
Juan Li, Li-Jun Ma, Xiao-Yuan Ma, Bo Gao
Juan Li, Department of Neurology, Xingyuan Hospital of Yulin/4th Hospital of Yulin, Yulin 719000, Shaanxi Province, China
Li-Jun Ma, Department of Clinical Laboratory, The Affiliated Hospital of Yan’an University, Yan’an 716000, Shaanxi Province, China
Xiao-Yuan Ma, Department of Operating Theater, The Affiliated Hospital of Yan’an University, Yan’an 716000, Shaanxi Province, China
Bo Gao, Department of Neurology, The Affiliated Hospital of Yan’an University, Yan’an 716000, Shaanxi Province, China
Author contributions: Li J, Ma LJ, and Gao B designed the methodology; Li J and Ma LJ performed the formal analysis of the data; Li J wrote the original draft; Li J and Gao B conceptualized the study; Ma LJ and Ma XY edited the various iterations of the manuscript; Gao B wrote and edited the manuscript, and performed the project administration.
Institutional review board statement: The National Health and Nutrition Examination Survey protocol is reviewed and approved by the National Center for Health Statistics Research Ethics Review Board, with informed consent obtained from all participants. The National Health and Nutrition Examination Survey data are publicly accessible, allowing any interested parties to obtain the full dataset by visiting the official website (https://www.cdc.gov/nchs/nhanes/index.htm).
Informed consent statement: The need for patient consent was waived due to the retrospective nature of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bo Gao, MD, Department of Neurology, The Affiliated Hospital of Yan’an University, No. 94 Shuangyong Avenue, Baota District, Yan’an 716000, Shaanxi Province, China. bobo0426@yau.edu.cn
Received: August 30, 2024
Revised: December 12, 2024
Accepted: January 20, 2025
Published online: March 19, 2025
Processing time: 180 Days and 3.6 Hours
Core Tip

Core Tip: Weight-to-waist index (WWI) is designed to evaluate central obesity, a condition strongly linked to a spectrum of metabolic and cardiovascular diseases. This study aims to elucidate the relationship between WWI and post-stroke depression (PSD) by analyzing data from the National Health and Nutrition Examination Survey from 2005 to 2018. There was a significant association between elevated WWI values and PSD risk. Individuals with higher WWI range exhibited more than double the likelihood of developing PSD compared to those with lower WWI values. As an emerging indicator of central obesity, WWI may serve as a valuable tool for assessing PSD risk.