Observational Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Jul 19, 2024; 14(7): 1062-1067
Published online Jul 19, 2024. doi: 10.5498/wjp.v14.i7.1062
Clinical study of chemotherapy-related cognitive impairment in patients with non-Hodgkin lymphoma
Qiang-Li Wang, Hai-Yan Xu, Yi Wang, Yin-Ling Wang, Pei-Nan Lin, Zhong-Lei Chen
Qiang-Li Wang, Hai-Yan Xu, Yi Wang, Yin-Ling Wang, Pei-Nan Lin, Zhong-Lei Chen, Department of Oncology and Hematology, Suzhou Kowloon Hospital, Shanghai Jiao Tong University School of Medicine, Suzhou 215000, Jiangsu Province, China
Author contributions: Wang QL and Chen ZL designed the study; Wang QL, Chen ZL, Xu HY, Wang Y, Wang YL, and Lin PN performed the research; Wang QL, Chen ZL, Xu HY, Wang Y, Wang YL, and Lin PN contributed new reagents and analytical tools; Wang QL and Chen ZL analyzed the data and wrote the manuscript; All authors have read and approved the final version of the manuscript.
Institutional review board statement: The study was reviewed and approved by the (Suzhou Kowloon Hospital, Shanghai Jiao Tong University School of Medicine) Institutional Review Board.
Informed consent statement: All study participants or their legal guardians provided written informed consent prior to their participation in this study.
Conflict-of-interest statement: All authors declare that they have nothing to disclose.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE statement-checklist of items, and the manuscript was prepared and revised according to the STROBE statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhong-Lei Chen, MMed, Associate Chief Physician, Department of Oncology and Hematology, Suzhou Kowloon Hospital, Shanghai Jiao Tong University School of Medicine, No. 118 WanSheng Street, Suzhou 215000, Jiangsu Province, China.chenzhonglei163@163.com
Received: April 8, 2024
Revised: May 7, 2024
Accepted: May 30, 2024
Published online: July 19, 2024
Processing time: 94 Days and 18.2 Hours
Core Tip

Core Tip: The cognitive status of patients with non-Hodgkin’s lymphoma before and after chemotherapy was assessed using various cognitive scales. We observed chemotherapy-related cognitive impairment. Patients with non-Hodgkin’s lymphoma undergoing chemotherapy may experience chemotherapy-related cognitive impairment. The main manifestations were language, memory, and visuospatial dysfunction. Frontal lobe injury was more obvious, but no clear difference was observed in executive function.