Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. May 19, 2024; 14(5): 653-660
Published online May 19, 2024. doi: 10.5498/wjp.v14.i5.653
Clinical effects of nonconvulsive electrotherapy combined with mindfulness-based stress reduction and changes of serum inflammatory factors in depression
Zhi-Wen Gu, Chun-Ping Zhang, Li-Ping Chen, Xiong Huang
Zhi-Wen Gu, Li-Ping Chen, Department of Psychiatry, Guangzhou First People's Hospital, South China University of Technology, Guangzhou 510180, Guangdong Province, China
Chun-Ping Zhang, Xiong Huang, Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou HuiAi Hospital), Guangzhou 510370, Guangdong Province, China
Co-corresponding authors: Li-Ping Chen and Xiong Huang.
Author contributions: Gu ZW, Chen LP, and Huang X conceived, designed, and refined the study protocol; Gu ZW, Zhang CP, and Huang X were involved in data collection and analysis; and Gu ZW, Chen LP, and Huang X drafted the manuscript; all authors were involved in the critical review of the results and contributed to, read, and approved the final manuscript. Chen LP and Huang X contributed equally to this work as co-corresponding authors.
Supported by Guangdong Provincial Medical Scientific Research Fund Project, No. B2016109.
Institutional review board statement: This study was reviewed and approved by the Ethics Committee of Guangzhou HuiAi Hospital (2016005).
Informed consent statement: All study participants or their legal guardians provided written informed consent for personal and medical data collection before study enrolment.
Conflict-of-interest statement: Dr. Chen has nothing to disclose.
Data sharing statement: The datasets used in this study can be obtained from the corresponding author.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Li-Ping Chen, MD, Associate Chief Physician, Department of Psychiatry, Guangzhou First People's Hospital, South China University of Technology, No. 1 Panfu Road, Yuexiu District, Guangzhou 510180, Guangdong Province, China. lpingchen@126.com
Received: December 22, 2023
Revised: January 13, 2024
Accepted: April 12, 2024
Published online: May 19, 2024
Processing time: 146 Days and 6.2 Hours
Core Tip

Core Tip: Nonconvulsive electrotherapy (NET) is a promising therapy for depression; however, its clinical effects and underlying mechanisms remain unclear. We conducted a retrospective analysis of data from 140 patients with depression. The control group received mindfulness-based stress reduction (MBSR) therapy, whereas the observation group received a combination of MBSR therapy and NET. Alterations in serum inflammatory factor levels have been observed, suggesting that NET exerts a therapeutic effect by modulating inflammatory levels. This study provides valuable insights for future investigations of the mechanisms underlying the role of NET in depression.