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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Nov 19, 2024; 14(11): 1696-1707
Published online Nov 19, 2024. doi: 10.5498/wjp.v14.i11.1696
Published online Nov 19, 2024. doi: 10.5498/wjp.v14.i11.1696
Resting-state functional magnetic resonance imaging and support vector machines for the diagnosis of major depressive disorder in adolescents
Zhi-Hui Yu, Ren-Qiang Yu, Xing-Yu Wang, Wen-Yu Ren, Xiao-Qin Zhang, Wei Wu, Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
Xiao Li, Lin-Qi Dai, Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
Ya-Lan Lv, School of Medical Informatics, Chongqing Medical University, Chongqing 400016, China
Author contributions: Yu ZH performed the literature search, collected the data and drafted and approved the final manuscript; Yu RQ conceived the idea and designed the study; Wang XY and Ren WY conducted magnetic resonance imaging scans on the subjects and approved the final manuscript; Yu RQ, Zhang XQ and Wu W reviewed the draft and approved the final manuscript; Li X and Dai LQ completed the clinical scale assessments of the subjects and approved the final manuscript; Lv YL analyzed the data and approved the final manuscript; All the authors contributed to this manuscript.
Institutional review board statement: This study was reviewed and approved by the local ethical review board (The First Affiliated Hospital of Chongqing Medical University, No. 20214801).
Informed consent statement: All the individuals who participated in this study provided their written informed consent prior to study enrolment.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—a checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-a checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ren-Qiang Yu, PhD, Doctor, Lecturer, Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing 400016, China. yurenqiang@hospital.cqmu.edu.cn
Received: May 26, 2024
Revised: October 9, 2024
Accepted: October 30, 2024
Published online: November 19, 2024
Processing time: 165 Days and 4 Hours
Revised: October 9, 2024
Accepted: October 30, 2024
Published online: November 19, 2024
Processing time: 165 Days and 4 Hours
Core Tip
Core Tip: We want to explore the potential neuroimaging biomarkers of adolescents with major depressive disorder using resting-state functional magnetic resonance imaging and support vector machines. The results showed that using the abnormal functional connectivity value of the right linguistic gyrus as a biomarker to distinguish patients and healthy controls had certain advantages, which was of great significance for the early diagnosis and treatment of adolescent major depressive disorder.