Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Nov 19, 2024; 14(11): 1641-1651
Published online Nov 19, 2024. doi: 10.5498/wjp.v14.i11.1641
Family functioning mediation in tic severity and quality of life for children with Tourette syndrome
Shu-Jin Hu, Ying Li, Qing-Hao Yang, Kai Yang, Jin-Hyun Jun, Yong-Hua Cui, Tian-Yuan Lei
Shu-Jin Hu, Ying Li, Qing-Hao Yang, Kai Yang, Jin-Hyun Jun, Yong-Hua Cui, Tian-Yuan Lei, Department of Psychiatry, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing 100045, China
Co-corresponding authors: Yong-Hua Cui and Tian-Yuan Lei.
Author contributions: Hu SJ, Li Y, Cui YH, and Lei TY designed the research study; Hu SJ, Li Y, Yang QH, Yang K, and Jun JH performed the research; Yang K and Lei TY contributed new reagents and analytic tools; Hu SJ and Lei TY analyzed the date and wrote the manuscript. All authors have read and approve the final manuscript. Lei TY and Cui YH contributed to this manuscript equally, they are co-corresponding authors of this manuscript.
Supported by the National Natural Science Foundation of China, No. 82171538; and the Beijing High Level Public Health Technology Talent Construction Project, No. Discipline Leader-01-07.
Institutional review board statement: This investigation was approved by the Institutional Ethics Committee of Capital Medical University Hospital, No. [2023]-E-05-R.
Informed consent statement: The need for patient consent was waived due to the retrospective nature of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tian-Yuan Lei, PhD, Assistant Professor, Department of Psychiatry, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, No. 56 Nanlishi Road, Beijing 100045, China. tianyuanlei@bch.com.cn
Received: April 10, 2024
Revised: September 20, 2024
Accepted: October 15, 2024
Published online: November 19, 2024
Processing time: 211 Days and 5.7 Hours
Core Tip

Core Tip: This was a retrospective study using a mediating effect model designed to investigate the role of family functioning in the relationship between Tourette syndrome severity and quality of life in children. The abnormal family communication function significantly mediated the relationship between the severity of Tourette syndrome and the quality of life of children. The effect was different between boys and girls and between children with and without attention-deficit hyperactivity disorder.