Sobanski T, Peikert G, Kastner UW, Wagner G. Suicidal behavior-advances in clinical and neurobiological research and improvement of prevention strategies. World J Psychiatry 2022; 12(9): 1115-1126 [PMID: 36186502 DOI: 10.5498/wjp.v12.i9.1115]
Corresponding Author of This Article
Thomas Sobanski, MD, Chief Doctor, Senior Lecturer, Senior Research Fellow, Department of Psychiatry, Psychotherapy, and Psychosomatic Medicine, THUERINGEN-Kliniken GmbH, 68 Rainweg, Saalfeld 07318, Germany. tsobanski@thueringen-kliniken.de
Research Domain of This Article
Psychiatry
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Psychiatry. Sep 19, 2022; 12(9): 1115-1126 Published online Sep 19, 2022. doi: 10.5498/wjp.v12.i9.1115
Suicidal behavior-advances in clinical and neurobiological research and improvement of prevention strategies
Thomas Sobanski, Gregor Peikert, Ulrich W Kastner, Gerd Wagner
Thomas Sobanski, Department of Psychiatry, Psychotherapy, and Psychosomatic Medicine, THUERINGEN-Kliniken GmbH, Saalfeld 07318, Germany
Thomas Sobanski, Ulrich W Kastner, Gerd Wagner, Network for Suicide Prevention in Thuringia (NeST), Jena 07743, Germany
Gregor Peikert, Gerd Wagner, Department of Psychiatry and Psychotherapy, University Hospital Jena, Jena 07743, Germany
Ulrich W Kastner, Department of Psychiatry and Psychotherapy, Helios Fachkliniken Hildburghausen, Hildburghausen 98646, Germany
Author contributions: Sobanski T, Peikert G, Kastner UW, and Wagner G contributed to this paper with conception, literature review and analysis, drafting and critical revision and editing, and approval of the final version.
Conflict-of-interest statement: Thomas Sobanski, Gregor Peikert, and Gerd Wagner have nothing to disclose. Ulrich W. Kastner owns shares in a healthcare company (Fresenius LTIP 2018, long-term incentive plan). However, this company is not active in the field of psychiatry or neuroscience. Thus, there is no content or technical reference.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Thomas Sobanski, MD, Chief Doctor, Senior Lecturer, Senior Research Fellow, Department of Psychiatry, Psychotherapy, and Psychosomatic Medicine, THUERINGEN-Kliniken GmbH, 68 Rainweg, Saalfeld 07318, Germany. tsobanski@thueringen-kliniken.de
Received: April 13, 2022 Peer-review started: April 13, 2022 First decision: June 11, 2022 Revised: June 26, 2022 Accepted: August 15, 2022 Article in press: August 15, 2022 Published online: September 19, 2022 Processing time: 160 Days and 3.1 Hours
Core Tip
Core Tip: This Editorial highlights recent developments concerning suicide prevention. According to current research, measures such as restricting access to lethal means and school-based awareness programs are the most efficacious universal prevention strategies. Novel psychological screening methods for suicidal behavior (implicit cognition, smartphone-based interventions, and real-time monitoring) have improved suicide risk assessment. Pharmacoepidemiological studies and meta-analyses support a protective role of antidepressants, lithium, and clozapine. Promising results exist for ketamine in reducing suicidal ideation. However, its suicide-preventive effect is under debate. Specific psychotherapeutic approaches for suicide attempters that focus on suicidal episodes proved to be efficacious for reducing suicide re-attempts.
