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©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Jul 19, 2022; 12(7): 874-883
Published online Jul 19, 2022. doi: 10.5498/wjp.v12.i7.874
Published online Jul 19, 2022. doi: 10.5498/wjp.v12.i7.874
SARS-CoV-2 consequences for mental health: Neuroinflammatory pathways linking COVID-19 to anxiety and depression
Anna Julie de Mello, Morgana Moretti, Ana Lúcia S Rodrigues, Department of Biochemistry, Universidade Federal de Santa Catarina, Florianópolis 88040-200, Brazil
Author contributions: Rodrigues ALS, Moretti M and de Mello AJ conceptualized the manuscript; de Mello AJ wrote the manuscript draft and prepared the figure; Rodrigues ALS and Moretti M reviewed and edited the final manuscript.
Supported by Conselho Nacional de Desenvolvimento Científico e Tecnológico , No. 312215/2021-5 .
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ana Lúcia S Rodrigues, PhD, Full Professor, Senior Scientist, Department of Biochemistry, Universidade Federal de Santa Catarina, Center of Biological Sciences, Florianópolis 88040-200, Brazil. alsrodri@gmail.com
Received: January 20, 2022
Peer-review started: January 20, 2022
First decision: April 18, 2022
Revised: May 3, 2022
Accepted: June 16, 2022
Article in press: June 16, 2022
Published online: July 19, 2022
Peer-review started: January 20, 2022
First decision: April 18, 2022
Revised: May 3, 2022
Accepted: June 16, 2022
Article in press: June 16, 2022
Published online: July 19, 2022
Core Tip
Core Tip: The coronavirus disease 2019 pandemic has impacted the mental health of the population worldwide. This review summarizes the evidence of the role of neuroinflammation, either as a result of chronic stress caused by the pandemic or severe acute respiratory syndrome coronavirus 2 infection, in the development of anxiety and depressive disorders.