Systematic Reviews
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Apr 19, 2022; 12(4): 623-635
Published online Apr 19, 2022. doi: 10.5498/wjp.v12.i4.623
Psychiatric comorbidities in cancer survivors across tumor subtypes: A systematic review
Anne Bach, Klara Knauer, Johanna Graf, Norbert Schäffeler, Andreas Stengel
Anne Bach, Klara Knauer, Johanna Graf, Norbert Schäffeler, Andreas Stengel, Section Psychooncology, Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Tübingen 72076, Germany
Andreas Stengel, Germany & Charité Center for Internal Medicine and Dermatology, Department for Psychosomatic Medicine, Charite-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin 10117, Germany
Author contributions: Bach A wrote the paper; Bach A, Knauer K and Graf J screened the literature; Graf J and Stengel A planned and supervised the project and thoroughly revised the paper; Schäffeler N thoroughly revised the paper.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Andreas Stengel, MD, PhD, Professor, Section Psychooncology, Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Osianderstr 5, Tübingen 72076, Germany. andreas.stengel@med.uni-tuebingen.de
Received: August 31, 2021
Peer-review started: August 31, 2021
First decision: December 12, 2021
Revised: December 20, 2021
Accepted: March 6, 2022
Article in press: March 6, 2022
Published online: April 19, 2022
Processing time: 224 Days and 11 Hours
Core Tip

Core Tip: Psychiatric disorders are a common comorbidity in cancer survivors, even years after diagnosis. Studies have found that tumor type has an effect on the prevalence of clinically relevant depression, anxiety, comorbid anxiety-depression and posttraumatic stress disorder. This systematic review compared the prevalence of these four psychiatric disorders in cancer survivors among tumor types. The results suggest that there are variations in the prevalence of all comorbidities across and within cancer types. A future direction should be the development of a screening tool to regularly assess cancer survivors’ psychological distress for at least 10 years after the initial disease.