Su YR, Yu XP, Huang LQ, Xie L, Zha JS. Factors influencing postoperative anxiety and depression following Iodine-131 treatment in patients with differentiated thyroid cancer: A cross-sectional study. World J Psychiatry 2023; 13(7): 486-494 [PMID: 37547735 DOI: 10.5498/wjp.v13.i7.486]
Corresponding Author of This Article
Jin-Shun Zha, MBBS, Chief Physician, Department of Nuclear Medicine, The Second Affiliated Hospital of Fujian Medical University, No. 34 North Zhongshan Road, Licheng District, Quanzhou 362000, Fujian Province, China. zjs630805@126.com
Research Domain of This Article
Psychiatry
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Psychiatry. Jul 19, 2023; 13(7): 486-494 Published online Jul 19, 2023. doi: 10.5498/wjp.v13.i7.486
Factors influencing postoperative anxiety and depression following Iodine-131 treatment in patients with differentiated thyroid cancer: A cross-sectional study
Jin-Shun Zha, Long Xie, Li-Qun Huang, Xiao-Peng Yu, Ying-Rui Su
Ying-Rui Su, Xiao-Peng Yu, Li-Qun Huang, Long Xie, Jin-Shun Zha, Department of Nuclear Medicine, The Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, Fujian Province, China
Author contributions: Su YR designed and performed the study and wrote the paper; Zha JS designed the study and supervised the report; Su YR designed the study and contributed to the analysis; Yu XP, Huang LQ, and Xie L provided clinical advice.
Supported byFujian Science and Technology Plan Project, No. 2022J01784.
Institutional review board statement: This Second Affiliated Hospital of Fujian Medical University reviewed and approved the study.
Informed consent statement: All study participants signed the informed consent forms.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The dataset available from the corresponding author at zjs630805@126.com.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jin-Shun Zha, MBBS, Chief Physician, Department of Nuclear Medicine, The Second Affiliated Hospital of Fujian Medical University, No. 34 North Zhongshan Road, Licheng District, Quanzhou 362000, Fujian Province, China. zjs630805@126.com
Received: May 19, 2023 Peer-review started: May 19, 2023 First decision: June 1, 2023 Revised: June 7, 2023 Accepted: June 13, 2023 Article in press: June 13, 2023 Published online: July 19, 2023 Processing time: 60 Days and 4.1 Hours
ARTICLE HIGHLIGHTS
Research background
Patients were investigated using the self-rating depression scale (SDS) and self-rating scales (SAS). Patients were grouped according to the presence and degree of anxiety and depression. The influencing factors were analyzed, and the appropriate intervention was suggested.
Research motivation
Patients with differentiated thyroid cancer (DTC) after 131I treatment were more prone to anxiety and depression. Clinically, female patients with no spouse, low education level, and low family income, accompanied by basic diseases, and medication irregularity should receive intervention care, thereby reducing the risk of anxiety and depression and improving their prognosis.
Research objectives
The original mean score of SAS and SDS was 50.06 ± 16.10 and 50.96 ± 16.55, respectively; 48.62% (70/144) and 47.22% (68/144) of the patients experiences anxiety and depression, respectively. Educational level, average monthly family income, and medication compliance influenced anxiety. Sex, marital status, and underlying diseases influenced depression (P < 0.05).
Research methods
We analyzed 144 patients with thyroid cancer after surgery who received 131I treatment in our hospital from June 2020 to December 2022. The patients were grouped according to their SDS and SAS scores. Single factor and multivariate analyses were used to determine the factors influencing anxiety and depression in patients with DTC after surgery.
Research results
It is crucial analyze the anxiety status and the related risk factors in patients with DTC after surgery, in order to formulate clinical preventive nursing strategies to improve the prognosis of patients.
Research conclusions
This study discussed the anxiety and depression status of patients with DTC after 131I treatment and analyzed their influencing factors.
Research perspectives
Patients with DTC do not comprehend 131I treatment, which is a type of internal radiotherapy, and they easily experience anxiety, fear, depression, and other negative emotions.
