Cheng G, Li XS, Zhang M, Wu YM. Investigation of factors influencing anxiety and depression symptoms after therapy in 200 patients diagnosed with primary liver cancer. World J Psychiatry 2025; 15(5): 101450 [DOI: 10.5498/wjp.v15.i5.101450]
Corresponding Author of This Article
Yan-Min Wu, Department of Digestive Internal Medicine, Affiliated Hospital of Jiangnan University, No. 1000 Hefeng Road, Binhu District, Wuxi 214000, Jiangsu Province, China. wym19850225@163.com
Research Domain of This Article
Psychiatry
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Psychiatry. May 19, 2025; 15(5): 101450 Published online May 19, 2025. doi: 10.5498/wjp.v15.i5.101450
Investigation of factors influencing anxiety and depression symptoms after therapy in 200 patients diagnosed with primary liver cancer
Gang Cheng, Xin-Sheng Li, Meng Zhang, Yan-Min Wu
Gang Cheng, Xin-Sheng Li, Meng Zhang, Department of Interventional Therapy, Affiliated Hospital of Jiangnan University, Wuxi 214000, Jiangsu Province, China
Yan-Min Wu, Department of Digestive Internal Medicine, Affiliated Hospital of Jiangnan University, Wuxi 214000, Jiangsu Province, China
Author contributions: Cheng G designed the study; Cheng G, Li XS, Zhang M, and Wu YM performed the research; Li XS and Zhang M analyzed the data and drafted the manuscript. All authors have read and approved the final manuscript submitted for publication.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Committee of the Affiliated Hospital of Jiangnan University, No. LS2022038.
Informed consent statement: All study participants or their legal guardians provided written informed consent for personal and medical data collection before study enrolment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No other available data.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan-Min Wu, Department of Digestive Internal Medicine, Affiliated Hospital of Jiangnan University, No. 1000 Hefeng Road, Binhu District, Wuxi 214000, Jiangsu Province, China. wym19850225@163.com
Received: January 8, 2025 Revised: February 19, 2025 Accepted: March 24, 2025 Published online: May 19, 2025 Processing time: 112 Days and 1.2 Hours
Abstract
BACKGROUND
Patients undergoing interventional therapy for liver cancer experience severe psychological pain and are prone to anxiety and depression.
AIM
To explore factors influencing anxiety and depression symptoms in 200 patients diagnosed with primary liver cancer.
METHODS
Data from 200 individuals diagnosed with primary liver cancer and admitted to the authors’ hospital (January 2022 to January 2024) were divided into 2 groups according to psychological status: Normal (n = 100); and anxiety and depression (n = 100). Through a questionnaire survey of patients and their families, single and multifactor factors of anxiety and depression in the postoperative interventional treatment of patients with primary liver cancer were analyzed.
RESULTS
Univariate analysis revealed no statistical differences between the 2 groups in terms of chronic disease, sex, liver function, Child grade, and age (P > 0.05). However, there were statistical differences in payment method, disease cognition, number of interventional treatments, per capita income, and educational level (P < 0.05). Multivariate logistic regression analysis revealed that educational level, per capita income, disease cognition, payment method, and number of interventional treatments were all independent factors influencing postoperative anxiety and depression symptoms after interventional therapy in patients diagnosed with primary liver cancer, and the comparisons were statistically significant (P < 0.05).
CONCLUSION
Analysis of associated risk factors can strengthen the clinical screening of patients with liver cancer at high risk for postoperative anxiety and depression symptoms and improve their prognosis.
Core Tip: A positive attitude can significantly benefit patients diagnosed with liver cancer. It helps them better cope with the physical and emotional challenges caused by the disease. Patients with a positive mindset are often more motivated to adhere to treatment plans and maintain a healthier lifestyle. This, in turn, can accelerate the rehabilitation process after treatment and improve overall quality of life.
