Abolfazli P, Apue Nchama CN, Lucke-Wold B. Optimizing chemotherapy outcomes: The role of mindfulness in Epirubicin treatment for urinary tumors. World J Psychiatry 2025; 15(4): 102852 [DOI: 10.5498/wjp.v15.i4.102852]
Corresponding Author of This Article
Brandon Lucke-Wold, MD, PhD, Lillian S. Wells Department of Neurosurgery, University of Florida, 1505 SW Archer Road, Gainesville, FL 32608, United States. brandon.lucke-wold@neurosurgery.ufl.edu
Research Domain of This Article
Psychiatry
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Pouria Abolfazli, Cristina Nkene Apue Nchama, Health Science Center, Xi'an Jiaotong University, Xi’an 710061, Shaanxi Province, China
Brandon Lucke-Wold, Lillian S. Wells Department of Neurosurgery, University of Florida, Gainesville, FL 32608, United States
Author contributions: Abolfazli P and Lucke-Wold B designed the overall concept and outline of the manuscript; Apue Nchama CN contributed to the discussion and design of the manuscript; Abolfazli P, Apue Nchama CN, and Lucke-Wold B contributed to this paper, the writing, and editing the manuscript and review of literature; all of the authors read and approved the final version of the manuscript to be published.
Conflict-of-interest statement: Abolfazli P, Apue Nchama CN, and Lucke-Wold B have nothing to disclose.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Brandon Lucke-Wold, MD, PhD, Lillian S. Wells Department of Neurosurgery, University of Florida, 1505 SW Archer Road, Gainesville, FL 32608, United States. brandon.lucke-wold@neurosurgery.ufl.edu
Received: October 31, 2024 Revised: January 21, 2025 Accepted: February 5, 2025 Published online: April 19, 2025 Processing time: 145 Days and 21.4 Hours
Abstract
This manuscript comments on the article published in a recent issue of World Journal of Psychology. We emphasize the potential of combining Epirubicin (EPI) chemotherapy with mindfulness-based interventions (MBIs) to optimize cancer care for urinary system tumors. The long-term use EPI is associated with depression and in short-term has shown side effects such as fatigue, nausea, and occasional abdominal pain, which can impact patient adherence. MBIs address the psychological burdens, such as depression and anxiety, that accompany cancer treatment, enhancing emotional well-being, immune function, and treatment adherence. Integration of MBIs alongside EPI offers improved clinical outcomes by lowering stress and reducing side effects, ultimately supporting both psychological and physical recovery. This comprehensive care model can potentially promote long-term health and quality of life for cancer patients.
Core Tip: Urinary system tumors often cause varying degrees of negative psychological symptoms, such as depression and dysphoria. These psychological factors significantly impact patients’ immune function and indirectly affect the intervention and prognosis of patients with cancer. Epirubicin (EPI) can improve the prognosis of patients with urinary system tumors, but it also has certain side effects. Mindfulness interventions are beneficial for enhancing psychological adaptability in cancer patients. In this study, the combination of EPI and mindfulness intervention achieved remarkable clinical results in patients with depression-complicated urinary system tumors.
