Clinical Trials Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Apr 19, 2025; 15(4): 101256
Published online Apr 19, 2025. doi: 10.5498/wjp.v15.i4.101256
Influence of cervical balloon fluid volume on maternal labor process, maternal and infant outcomes, and pregnancy-related anxiety
Ni Wang, Jie Zhou, Li-Juan Ding, Li Qian, Chen Chen, Xiao-Shi Wang, Na Xu
Ni Wang, Li-Juan Ding, Li Qian, Chen Chen, Na Xu, Department of Obstetrical, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi 214000, Jiangsu Province, China
Jie Zhou, Department of Obstetrics and Gynecology,Wuxi Huishan District People’s Hospital,Affiliated Huishan Hospital Of Xinglin College,Nantong University, Wuxi 214000, Jiangsu Province, China
Xiao-Shi Wang, Department of Gynecology, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi 214000, Jiangsu Province, China
Co-first authors: Ni Wang and Jie Zhou.
Author contributions: Wang N and Zhou J contributed equally to this work; Wang N designed the study; Wang N, Zhou J, Ding LJ, Qian L, Chen C, Wang XS, and Xu N contributed to the analysis of the manuscript; Wang N, Zhou J, Ding LJ, Qian L, Chen C, Wang XS, and Xu N were involved in the data and writing of this article; Wang N and Zhou J are jointly responsible for data collection, design research, and have made equal contributions to this article; All authors have read and approved the final manuscript.
Supported by the Wuxi Municipal Health Commission Maternal and Child Health Research Project, No. FYKY202202.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, No. (2023) Research Ethics Review No. KY23123.
Clinical trial registration statement: The study was registered at the Clinical Trial Center (www.researchregistry.com) with registration number: Researchregistry10987.
Informed consent statement: All study participants and their legal guardians provided written informed consent before recruitment.
Conflict-of-interest statement: The authors declare no conflicts of interest.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Na Xu, Chief Physician, Department of Obstetrical, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, No. 299 Qingyang Road, Liangxi District, Wuxi 214000, Jiangsu Province, China. 1649578586@qq.com
Received: December 27, 2024
Revised: January 23, 2025
Accepted: February 21, 2025
Published online: April 19, 2025
Processing time: 88 Days and 2.8 Hours
Abstract
BACKGROUND

The full implementation of the national two-child policy has presented significant challenges in ensuring the safety of pregnant women.

AIM

To investigate the effect of cervical balloon fluid volume on maternal processes, maternal and infant outcomes, and anxiety during pregnancy.

METHODS

A total of 100 singleton term pregnancies with cervical maturity induction and anxiety were selected using a lottery method; 50 women were included. Cervical balloons were used for all participants. In the control group, 80 mL of fluid was injected into both balloons; in the observation group, 80 and 100 mL were injected into the vaginal and cervical balloons, respectively. The two groups were compared for cervical maturity, labor duration, anxiety, maternal and infant outcomes, and effects on cervical ripening.

RESULTS

After treatment, the cervical maturity test (Bishop) score was significantly higher in the observation group (9.76 ± 1.19) than in the control group (7.62 ± 0.83), and the Hamilton Anxiety Scale score was lower in the observation group (7.32 ± 0.85) than in the control group (13.05 ± 1.12). The observation group showed higher rates of natural delivery and lower rates of cesarean section than the control group. The first and total stages of labor were shorter in the observation than in the control group; no significant differences were found in the second and third stages. The incidence of complications was lower in the observation group [1 (2.00%) vs 9 (18.00%) for complications; 49 (98.00%) vs 41 (82.00%) for non-complications].

CONCLUSION

The selected fluid volumes to promote cervical maturity and induce labor stabilize maternal mood, increase the natural delivery rate, shorten labor, and improve maternal and infant outcomes.

Keywords: Cervical balloon fluid volume; Singleton pregnancy; Cervical ripening; Anxiety state; Maternal labor process

Core Tip: Cervical maturity is an important factor in determining the success of labor induction and is crucial for improving the success rate of labor induction and shortening the time from labor induction to delivery.