Huseynov A, Satici B. Future anxiety mediates the relationship between organ donation and transplantation knowledge and health-related quality of life. World J Psychiatry 2025; 15(3): 103175 [DOI: 10.5498/wjp.v15.i3.103175]
Corresponding Author of This Article
Amil Huseynov, MD, Assistant Professor, Department of Transplantation, Istanbul Medicana International, Beylikduzu, İstanbul 34180, Türkiye. atu-boy@hotmail.com
Research Domain of This Article
Psychology, Multidisciplinary
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Psychiatry. Mar 19, 2025; 15(3): 103175 Published online Mar 19, 2025. doi: 10.5498/wjp.v15.i3.103175
Future anxiety mediates the relationship between organ donation and transplantation knowledge and health-related quality of life
Amil Huseynov, Begum Satici
Amil Huseynov, Department of Transplantation, Istanbul Medicana International, İstanbul 34180, Türkiye
Begum Satici, Department of Psychological Counseling, Yildiz Technical University, İstanbul 34180, Türkiye
Author contributions: Huseynov A and Satici B designed the study, participated in the formal analysis and investigation, wrote the original draft, and participated in the review and editing.; Huseynov A was responsible for developing the methodology.
Institutional review board statement: This study was approved by the relevant Yildiz Technical University Ethics Committee (No. 20241003353).
Informed consent statement: Informed consent was obtained from all participants.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Data sharing statement: Data will be made available on request at atu-boy@hotmail.com.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Amil Huseynov, MD, Assistant Professor, Department of Transplantation, Istanbul Medicana International, Beylikduzu, İstanbul 34180, Türkiye. atu-boy@hotmail.com
Received: November 11, 2024 Revised: December 27, 2024 Accepted: January 21, 2025 Published online: March 19, 2025 Processing time: 107 Days and 12.5 Hours
Abstract
BACKGROUND
Knowledge about organ donation and transplantation plays a crucial role in shaping individuals' health behaviors and perceptions, potentially impacting their health-related quality of life (HRQoL). Future anxiety, defined as the anticipatory worry individuals experience regarding potential negative events and outcomes in their future, may further influence these outcomes.
AIM
To investigate the effect of such knowledge on HRQoL and to examine whether future anxiety mediates this relationship.
METHODS
A cross-sectional study was conducted with 659 participants aged 18 to 65 years. Participants completed the Organ Tissue Donation and Transplantation Knowledge Scale, the Dark Future Scale, and the European Health Interview Survey-Quality of Life 8. Correlation analyses were performed, followed by Structural Equation Modeling to test the proposed mediation model.
RESULTS
The findings indicated that greater knowledge about organ donation and transplantation was positively associated with higher HRQoL and negatively associated with future anxiety. Future anxiety was negatively correlated with HRQoL. Structural Equation Modeling analysis indicated that knowledge directly enhanced HRQoL and reduced future anxiety. Additionally, future anxiety negatively affected HRQoL, mediating the relationship between knowledge and HRQoL. The mediation effect was significant, as confirmed by bootstrapping (bootstrap coefficient = 0.068, 95%CI: 0.046-0.093).
CONCLUSION
The study concludes that future anxiety partially mediates the positive impact of knowledge about organ donation and transplantation on HRQoL. These results suggest that increasing public knowledge in this area may reduce future anxieties and enhance quality of life.
Core Tip: This study explores the link between organ donation and transplantation knowledge and health-related quality of life (HRQoL), with a focus on the mediating role of future anxiety. Findings reveal that increased knowledge is associated with improved HRQoL and reduced future anxiety. Structural Equation Modeling shows that future anxiety partially mediates this relationship, indicating that reducing future anxiety can amplify the positive effects of knowledge on HRQoL. These results highlight the importance of educational interventions to boost public awareness, reduce anxiety, and promote overall well-being.
