Meta-Analysis
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Sep 19, 2024; 14(9): 1397-1403
Published online Sep 19, 2024. doi: 10.5498/wjp.v14.i9.1397
Early screening for post-stroke depression and its effect on functional outcomes, quality of life, and mortality: A meta-analysis
Jie Dai, Sha-Sha Zhao, Su-Xiang Zhang
Jie Dai, Sha-Sha Zhao, Su-Xiang Zhang, Department of Neurology 6, Cangzhou Central Hospital, Cangzhou 061001, Hebei Province, China
Author contributions: Dai J, Zhao SS and Zhang SX acquisition of data, analysis and interpretation of data, drafting the article, final approval; Dai J, Zhao SS interpretation of data, revising the article, final approval; Zhang SX conception and design of the study, critical revision, final approval.
Supported by Hebei Provincial Health Commission, No. 20200336.
Conflict-of-interest statement: The authors deny any conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jie Dai, MM, Associate Chief Physician, Department of Neurology 6, Cangzhou Central Hospital, No. 50 Xinhua West Road, Yunhe District, Cangzhou 061001, Hebei Province, China. bluemice_2004@163.com
Received: July 10, 2024
Revised: July 29, 2024
Accepted: August 15, 2024
Published online: September 19, 2024
Processing time: 62 Days and 19.2 Hours
Abstract
BACKGROUND

Post-stroke depression (PSD) is a common and debilitating condition affecting stroke survivors, significantly impacting their recovery and overall quality of life.

AIM

To assess the effects of early PSD screening on functional outcomes, quality of life, and mortality.

METHODS

From an initial pool of 1065 articles, 6 studies met the inclusion criteria and were selected for analysis. Functional outcomes were measured using the functional independence measure (FIM).

RESULTS

The analysis revealed a significant improvement in FIM scores for a PSD screening group compared to controls [standardized mean difference (SMD) = 8.90, 95% confidence interval (CI): 4.65-13.15, P < 0.01]. Quality of life was assessed using the Stroke-Specific Quality of Life Scale, with the screening group showing significantly higher scores (SMD = 20.83, 95%CI: 15.27-26.38, P < 0.01). Mortality analysis indicated a reduction in five-year mortality rates for the PSD screening group.

CONCLUSION

Early PSD screening enhances functional recovery, improves quality of life, and reduces mortality rates in stroke survivors. Thus, integrating PSD screening into routine stroke care improves long-term outcomes for patients.

Keywords: Post-stroke depression; Early screening; Functional outcomes; Quality of life; Mortality

Core Tip: Post-stroke depression (PSD) is a common and debilitating condition affecting stroke survivors, significantly impacting their recovery and overall quality of life. This meta-analysis aimed to assess the effects of early PSD screening on functional outcomes, quality of life, and mortality. The findings of the study highlight the potential benefits of early PSD screening in improving recovery and survival outcomes for patients with stroke. However, further research is necessary to standardize screening protocols and address potential limitations related to heterogeneity.