Observational Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Sep 19, 2024; 14(9): 1364-1374
Published online Sep 19, 2024. doi: 10.5498/wjp.v14.i9.1364
Analysis of risk factors for postoperative anxiety and depression in endometriosis patients with reproductive intention
Chun-Mei Wu, Cai-Hua Li, You-Yan Fang, Huan Wu, Dong-Mei Ji, Ping Zhou, Yun-Xia Cao, Ye He, Zhao-Lian Wei
Chun-Mei Wu, Cai-Hua Li, You-Yan Fang, Huan Wu, Dong-Mei Ji, Ping Zhou, Yun-Xia Cao, Ye He, Zhao-Lian Wei, Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei 230000, Anhui Province, China
Chun-Mei Wu, Department of Obstetrics and Gynecology, Huaibei People's Hospital of Anhui Province, Huaibei 235000, Anhui Province, China
Co-corresponding authors: Ye He and Zhao-Lian Wei.
Author contributions: He Y and Wei ZL contribute equally to this study as co-corresponding authors. Wu CM was responsible for writing of original draft, collect information, conceptualization, formal analysis; Li CH, Fang YY and Wu H were responsible for resources, supervision, methodology; Ji DM, Zhou P and He Y were responsible for formal analysis, investigation, and validation; Cao YX was responsible for software and data curation; Wei ZL was responsible for writing, review and editing.
Supported by Research Funds of Center for Big Data and Population Health of IHM, No. JKS2022009; Huaibei Science and Technology Plan Project, No. 2021HK016.
Institutional review board statement: The study was reviewed and approved by the First Affiliated Hospital of Anhui Medical University Institutional Review Board.
Informed consent statement: All study participants provided informed written consent before study enrollment.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhao-Lian Wei, MD, Chief Physician, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Shushan District, Hefei 230000, Anhui Province, China. weizhaolian_1@126.com
Received: July 24, 2024
Revised: August 13, 2024
Accepted: August 15, 2024
Published online: September 19, 2024
Processing time: 48 Days and 19.3 Hours
Abstract
BACKGROUND

The occurrence of postoperative depression and anxiety in patients with endometriosis (EMS) not only causes psychological distress, but may also harm their physical health.

AIM

To explore the postoperative depression status, and its influencing factors, of EMS patients with reproductive intention.

METHODS

A total of 321 EMS patients with reproductive intent were included. Using the self-rating anxiety scale and self-rating depression scale, EMS patients with anxiety or depression were distinguished. A clinical model for predicting anxiety or depression in EMS patients was constructed and evaluated using a nomogram, receiver operating characteristic curve, and calibration curve.

RESULTS

The results of the single factor analysis showed that smoking, coffee, EMS stage, chronic pelvic pain, and sexual discomfort may be related to anxiety. Further, smoking, drinking, spouse, annual household income and EMS stage may be related to depression in EMS patients. Multivariate logistic regression illustrated that smoking, coffee, chronic pelvic pain and sexual discomfort may be independent risk factors for anxiety in EMS patients, while smoking, EMS stage (Phase III and Phase IV), spouse and high annual household income may be independent risk factors for depression in EMS patients. Additionally, the models used to predict the risk of anxiety or depression in EMS patients have good predictive value.

CONCLUSION

The anxiety and depression of EMS patients may be related to many factors. In clinical treatment, additional attention should be paid to the psychological status of EMS patients.

Keywords: Endometriosis; Reproductive intention; Anxiety; Depressed

Core Tip: The occurrence of postoperative depression and anxiety in patients with endometriosis (EMS) not only causes psychological distress, but may also harm their physical health. This study included 321 EMS patients with fertility intentions. Evaluate the anxiety or depression of EMS patients using the self-rating anxiety scale and self-rating depression scale. A clinical model for predicting anxiety or depression in EMS patients was constructed based on multiple regression equations, and the results showed that the model for predicting the risk of anxiety or depression in EMS patients has good predictive value.