Observational Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Apr 19, 2024; 14(4): 541-552
Published online Apr 19, 2024. doi: 10.5498/wjp.v14.i4.541
Resilience provides mediating effect of resilience between fear of progression and sleep quality in patients with hematological malignancies
Yuan Tian, Ying-Li Wang
Yuan Tian, Department of Hematology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou 121000, Liaoning Province, China
Ying-Li Wang, Department of Cardiology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou 121000, Liaoning Province, China
Author contributions: Tian Y designed the questionnaire, conducted the statistical analysis of the data, and drafted the initial manuscript; Wang YL supervised and guided the study and revised the manuscript.
Institutional review board statement: This study was reviewed and approved by the First Affiliated Hospital of Jinzhou Medical University.
Informed consent statement: All study participants or their legal guardians provided written informed consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: Data used in this study were obtained from the corresponding author.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ying-Li Wang, MBBS, Nurse, Department of Cardiology, The First Affiliated Hospital of Jinzhou Medical University, No. 2 Section 5, People Street, Guta District, Jinzhou 121000, Liaoning Province, China. 13897850411@163.com
Received: January 19, 2024
Peer-review started: January 19, 2024
First decision: February 5, 2024
Revised: February 19, 2024
Accepted: March 28, 2024
Article in press: March 28, 2024
Published online: April 19, 2024
Processing time: 88 Days and 19.9 Hours
Abstract
BACKGROUND

Hematological tumors are common malignant tumors, with high morbidity and mortality rates. Most patients with hematological malignancies develop sleep disorders that seriously affect their life and health because of acute onset of disease, rapid progression, high recurrence rates, complex treatment methods, and treatment costs.

AIM

To explore the mediating effect of resilience on fear of disease progression and sleep quality in patients with hematological malignancies.

METHODS

A cross-sectional analysis of 100 patients with hematological malignancies, treated in the First Affiliated Hospital of Jinzhou Medical University between August 2022 and August 2023, was conducted. Patients were assessed using a general data survey, a simplified scale for the fear of progression (FoP) of disease, a resilience scale, and the Pittsburgh Sleep Quality Index. Statistical analysis was conducted to determine the relationship between various patient characteristics and FoP, resilience, and sleep quality. Spearman’s correlation analysis was used to examine the correlations between mental resilience, FoP, and sleep quality.

RESULTS

The total FoP score mean value in patients with hematological malignancies was 38.09 ± 5.16; the total resilience score mean value was 40.73 ± 7.04; and the Pittsburgh Sleep Quality Index score mean value was 10.72 ± 1.90. FoP, resilience, and sleep quality of the patients were associated with family per capita monthly income and patient education level (P < 0.05). Spearman correlation analysis revealed that FoP was negatively correlated with resilience and sleep quality scores (r = -0.560, -0.537, P < 0.01), respectively, and resilience was significantly associated with sleep quality scores (r = 0.688, P < 0.01). Mediation analysis showed that the mediating effect of resilience between FoP and sleep quality in patients with hematological malignancies was -0.100 and accounted for 50.51% of the total effect. This indicated that FoP directly and indirectly affected sleep quality through the mesomeric effect of resilience.

CONCLUSION

Resilience is an intermediary variable between FoP and sleep quality in patients with hematological malignancies. Medical staff should evaluate and follow-up FoP and resilience to implement measures to improve sleep quality.

Keywords: Resilience, Blood tumor, Fear of progression, Sleep quality, Mediating effect

Core Tip: Hematological tumors are common malignant tumors. Most patients with hematological malignancies develop sleep disorders that seriously affect their quality of life and health, owing to the acute onset, rapid progression, and high recurrence rate of these tumors. In this study, we conducted a cross-sectional analysis of 100 patients with hematological malignancies in the oncology department of our hospital. A general data survey, simplified fear of disease progression scale, resilience scale, and the Pittsburgh Sleep Quality Index were used to investigate the mediating effect of resilience between fear of disease progression and sleep quality in patients with hematological malignancies.