Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Dec 19, 2024; 14(12): 1788-1792
Published online Dec 19, 2024. doi: 10.5498/wjp.v14.i12.1788
Optimizing anesthesia depth to enhance seizure quality during electroconvulsive therapy in major depressive disorder
Haewon Byeon
Haewon Byeon, Department of Digital Anti-aging Healthcare (BK21), Inje University, Gimhae 50834, South Korea
Haewon Byeon, Inje University Medical Big Data Research Center, Gimhae 50834, South Korea
Author contributions: Byeon H contributed to this paper; Byeon H involved in data interpretation; Byeon H developed methodology; Byeon H writing the article.
Supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, No. NRF- RS-2023-00237287 and No. NRF-2021S1A5A8062526; and Local Government-University Cooperation-Based Regional Innovation Projects, No. 2021RIS-003.
Conflict-of-interest statement: No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Haewon Byeon, DSc, PhD, Associate Professor, Director, Department of Digital Anti-aging Healthcare (BK21), Inje University, No. 197 Injero, Gimhae 50834, South Korea. bhwpuma@naver.com
Received: September 5, 2024
Revised: November 2, 2024
Accepted: November 15, 2024
Published online: December 19, 2024
Processing time: 83 Days and 0.4 Hours
Abstract

This editorial evaluated the findings of a comprehensive study focused on the effects of anesthesia depth on seizure parameters during electroconvulsive therapy (ECT) in patients with major depressive disorder. The study utilized quantitative consciousness and quantitative nociceptive indices for monitoring sedation, hypnosis, and nociceptive responses. The analysis included 193 ECT sessions across 24 patients, revealing significant impacts of anesthesia depth on electroencephalography (EEG) seizure parameters. Key findings include that lighter anesthesia resulted in longer EEG seizure duration and higher post-ictal suppression index, without increasing complications. These insights emphasize the importance of optimal anesthesia management to improve therapeutic outcomes in ECT.

Keywords: Electroconvulsive therapy; Anesthesia depth; Major depressive disorder; Electroencephalography seizure parameters; Quantitative consciousness index; Quantitative nociceptive index; Seizure quality; Editorial

Core Tip: This editorial comments on the study by Zhao et al which evaluates the impact of anesthesia depth on electroencephalography (EEG) seizure parameters during electroconvulsive therapy (ECT) in patients with major depressive disorder. Utilizing quantitative consciousness and quantitative nociceptive indices, the study reveals that lighter anesthesia results in longer EEG seizure durations and higher post-ictal suppression index without increasing complications. These findings underscore the importance of optimal anesthesia management to improve therapeutic outcomes in ECT, providing valuable insights for refining clinical practices and enhancing patient care.