Wang GB, Zhang XF, Liang B, Lei J, Xue J. Study on the correlation between abdominal infection and psychological stress in children based on nucleic acid detection. World J Psychiatry 2024; 14(11): 1728-1734 [PMID: 39564175 DOI: 10.5498/wjp.v14.i11.1728]
Corresponding Author of This Article
Gui-Bo Wang, MM, Attending Doctor, Department of Pediatric Surgery, The First Affiliated Hospital of Hebei North University, No. 12 Changqing Road, Qiaoxi District, Zhangjiakou 075000, Hebei Province, China. heibaizhubobo@163.com
Research Domain of This Article
Medicine, General & Internal
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Psychiatry. Nov 19, 2024; 14(11): 1728-1734 Published online Nov 19, 2024. doi: 10.5498/wjp.v14.i11.1728
Study on the correlation between abdominal infection and psychological stress in children based on nucleic acid detection
Gui-Bo Wang, Xue-Feng Zhang, Bing Liang, Jie Lei, Jun Xue
Gui-Bo Wang, Xue-Feng Zhang, Bing Liang, Jie Lei, Department of Pediatric Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei Province, China
Jun Xue, Department of General Surgery, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei Province, China
Author contributions: Liang B, Lei J and Xue J were the guarantors and designed the study; Wang GB and Zhang XF participated in the acquisition, analysis, and interpretation of the data, and drafted the initial manuscript; Wang GB revised the article critically for important intellectual content.
Supported byZhangjiakou Science and Technology Tackling Program, No. 2021099D.
Institutional review board statement: The study was reviewed and approved by the Science and Research Office of The First Affiliated Hospital of Hebei North University, No. K2023176.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gui-Bo Wang, MM, Attending Doctor, Department of Pediatric Surgery, The First Affiliated Hospital of Hebei North University, No. 12 Changqing Road, Qiaoxi District, Zhangjiakou 075000, Hebei Province, China. heibaizhubobo@163.com
Received: August 26, 2024 Revised: September 25, 2024 Accepted: October 24, 2024 Published online: November 19, 2024 Processing time: 72 Days and 23.6 Hours
Abstract
BACKGROUND
Diagnosing and treating abdominal infection in children remains a challenge. Nucleic acid detection, as a rapid and accurate diagnosis tool, has great significance in this field.
AIM
To investigate the diagnosis and treatment of abdominal infection by nucleic acid detection and its possible correlation with psychological stress in children.
METHODS
A total of 50 pediatric patients diagnosed with abdominal infections between September 2020 and July 2021 were included in this study. Intra-abdominal pus samples were collected for pathogen culture, drug susceptibility testing, and broad-spectrum bacterial nucleic acid testing. Psychological stress, anxiety, depression, and coping styles were assessed using the coping with a disease (CODI) scale.
RESULTS
Based on susceptibility testing, a regimen of cefazoxime, piperacillin/tazobactam, and metronidazole or ornidazole achieved 100% effectiveness in treating appendicitis. Psychological assessments revealed a positive correlation between pressure level and both anxiety (r = 0.324, P = 0.001) and depressive disorders (r = 0.325, P < 0.001). Acceptance and distancing as coping strategies were negatively correlated with anxiety and depression, while negative emotional responses were strongly associated with increased anxiety (r = 0.574, P < 0.001) and depression (r = 0.511, P = 0.001). Coping strategies such as illusion and escape showed no significant correlation with emotional outcomes.
CONCLUSION
Nucleic acid testing helps in the diagnosis of abdominal infections in children, and also focuses on children's mental health.
Core Tip: To investigate the diagnosis and treatment of abdominal infection by nucleic acid detection and its possible correlation with psychological stress in children. After the study, we concluded that in clinical practice, nucleic acid detection can effectively assist the diagnosis and treatment of abdominal infection in children, and some patients show different degrees of anxiety or other psychological stress reactions when receiving nucleic acid detection. The study underscores the psychological impact of abdominal infections on children, revealing significant associations between perceived stress, anxiety, depression, and coping mechanisms. Promoting adaptive coping strategies like acceptance and distancing could help reduce the emotional distress experienced by these patients.
