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Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Dec 19, 2023; 13(12): 973-984
Published online Dec 19, 2023. doi: 10.5498/wjp.v13.i12.973
Risk factors, preventive interventions, overlapping symptoms, and clinical measures of delirium in elderly patients
Xi Mei, Yue-Hong Liu, Ya-Qing Han, Cheng-Ying Zheng
Xi Mei, Yue-Hong Liu, Ya-Qing Han, Cheng-Ying Zheng, Department of Psychiatry, Ningo Kangning Hospital, Ningbo 315201, Zhejiang Province, China
Author contributions: Mei X contributed to the original draft of the manuscript; Liu YH, Han YQ and Zheng CY proofread the manuscript; all authors have read and approved the final manuscript.
Supported by the NINGBO Medical & Health Leading Academic Discipline Project, No. 2022-F28.
Conflict-of-interest statement: The authors declare that they had no conflict of interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Cheng-Ying Zheng, BSc, Professor, Department of Psychiatry, Ningo Kangning Hospital, No. 1 Zhuangyu South Road, Zhenhai District, Ningbo 315201, Zhejiang Province, China. zhengchengying@126.com
Received: July 19, 2023
Peer-review started: July 19, 2023
First decision: September 4, 2023
Revised: September 14, 2023
Accepted: October 30, 2023
Article in press: October 30, 2023
Published online: December 19, 2023
Processing time: 153 Days and 12.9 Hours
Abstract

Delirium is an acute reversible neuropsychiatric syndrome caused by multiple factors. It is associated with many adverse clinical outcomes including cognitive impairment, functional decline, prolonged hospitalization, and increased nursing service. The prevalence of delirium was high in department of cardiology, geriatric, and intensive care unit of hospital. With the increase in the aged population, further increases in delirium seem likely. However, it remains poorly recognized in the clinical practice. This article comprehensively discusses the latest research perspectives on the epidemiological data, risk factors, preventive interventions, overlapping symptoms, and clinical measures of delirium, including specific measures to manage delirium in clinical real-world situations. This article helps readers improve their knowledge and understanding of delirium and helps clinicians quickly identify and implement timely therapeutic measures to address various delirium subtypes that occur in the clinical settings to ensure patients are treated as aggressively as possible.

Keywords: Delirium; Risk factors; Preventive interventions; Research progress; Review; Clinical practice

Core Tip: This paper reviews the whole delirium process and its latest research progress in risk factors, preventive interventions, identification of superimposed symptoms, and clinical measures to provide a comprehensive and systematic account of delirium and present the latest medical information. This article helps readers improve understanding of delirium and helps clinicians quickly identify and take timely therapeutic measures to address the various delirium subtypes that occur in the clinic setting. This is to ensure that patients can be treated as aggressively as possible.