|
1
|
Peng H, Yao N, Song YP, Huang L, Chen HB, Jiang Y, Chen QG. Motoric cognitive risk syndrome: A review of fall risk assessment and management strategies. World J Psychiatry 2025; 15:101800. [DOI: 10.5498/wjp.v15.i4.101800] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/26/2024] [Revised: 11/09/2024] [Accepted: 01/24/2025] [Indexed: 03/25/2025] Open
Abstract
The aging global population is driving an increase in dementia, making the early identification of at-risk individuals crucial. Studies have shown that elderly people often exhibit a slowing gait before dementia diagnosis, which is linked to cognitive decline and predicts dementia risk. With 30% of those over 65 years of age experiencing falls annually, managing fall risk is essential. Motoric cognitive risk syndrome (MCR), characterized by subjective memory impairment and slow gait, is a pre-dementia condition that can identify high-risk individuals without extensive evaluation. The prevalence of MCR varies globally and is associated with an increased risk of falls, disability, and death. Early screening and intervention for MCR can delay dementia and improve fall regulation, offering a new perspective on elderly health management. This review synthesizes the current understanding of MCR-related falls, evaluates risk assessment methods, and discusses health strategies to provide a theoretical basis for fall prevention in community-dwelling older adults.
Collapse
Affiliation(s)
- Hao Peng
- College of Physical Education, Yunnan Normal University, Kunming 650500, Yunnan Province, China
| | - Na Yao
- Department of Rehabilitation, Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming 650011, Yunnan Province, China
| | - Yan-Ping Song
- Department of Rehabilitation, Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming 650011, Yunnan Province, China
| | - Li Huang
- Department of Rehabilitation, Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming 650011, Yunnan Province, China
| | - Hong-Bo Chen
- Department of Rehabilitation, Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming 650011, Yunnan Province, China
| | - Yang Jiang
- College of Physical Education, Yunnan Normal University, Kunming 650500, Yunnan Province, China
| | - Qi-Gang Chen
- Department of Rehabilitation, Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming 650011, Yunnan Province, China
| |
Collapse
|
|
2
|
Leem J, Lemonnier T, Khutsaidze A, Tian L, Xing X, Bai S, Nottoli T, Mogessie B. A versatile cohesion manipulation system reveals CENP-A dysfunction accelerates female reproductive age-related egg aneuploidy. BIORXIV : THE PREPRINT SERVER FOR BIOLOGY 2025:2025.02.27.640570. [PMID: 40060401 PMCID: PMC11888391 DOI: 10.1101/2025.02.27.640570] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Grants] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Indexed: 03/15/2025]
Abstract
Female reproductive aging is accompanied by a dramatic rise in the incidence of egg aneuploidy. Premature loss of chromosome cohesion proteins and untimely separation of chromosomes is thought to underly high rates egg aneuploidy during maternal aging. However, because chromosome cohesion loss occurs gradually over female reproductive lifespan and cytoskeletal defects alone can predispose eggs to chromosomal abnormalities, the root causes of exponential rise in egg aneuploidy at advanced reproductive ages remain a mystery. Here, we applied high-resolution live imaging to visualize for the first time cohesion protein dynamics underpinning meiotic chromosome segregation. To discover proteins whose dysfunction accelerates aneuploidies associated with female reproductive aging, we innovated the first experimental system in which chemically induced cohesion reduction rapidly triggers aging-like chromosomal abnormalities in young eggs. By integrating this direct cohesion manipulation system with quantitative high-resolution microscopy and targeted protein degradation tools, we identified the centromeric protein CENP-A as a new factor whose aging-like depletion causes a dramatic rise in premature separation of sister chromatids. Our work illuminates cohesion loss-independent origins of age-related egg aneuploidy and provides new avenues to discover therapeutic targets for extending the female reproductive lifespan.
Collapse
Affiliation(s)
- Jiyeon Leem
- Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA
| | - Tom Lemonnier
- Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA
| | - Ani Khutsaidze
- Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA
| | - Lei Tian
- Yale Genome Editing Center, Yale University School of Medicine, New Haven, Connecticut, USA
| | - Xiaojun Xing
- Yale Genome Editing Center, Yale University School of Medicine, New Haven, Connecticut, USA
| | - Suxia Bai
- Department of Comparative Medicine, Yale Genome Editing Center, Yale University School of Medicine, New Haven, Connecticut, USA
| | - Timothy Nottoli
- Department of Comparative Medicine, Yale Genome Editing Center, Yale University School of Medicine, New Haven, Connecticut, USA
| | - Binyam Mogessie
- Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA
- Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, USA
| |
Collapse
|
|
3
|
Mobasseri K, Ghasemyani S, Khodayari-Zarnaq R, Kousha A. Developing a comprehensive model of home-based long-term care for older people in Iran: a multi-method study. BMC Health Serv Res 2025; 25:298. [PMID: 39987070 PMCID: PMC11846254 DOI: 10.1186/s12913-025-12434-0] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/11/2024] [Accepted: 02/14/2025] [Indexed: 02/24/2025] Open
Abstract
INTRODUCTION With the increasing aging population, the demand for care that fosters independence in older adults is rising. Complications from hospitalization and the preference for aging in place highlight the need for geriatric home care systems. This study aims to develop a comprehensive home-based care model specifically for Iranian seniors and evaluate its feasibility. METHODS This study employed a multi-phase approach in Iran. It began with a mixed-methods analysis, including a survey on caregiver reliance, followed by qualitative interviews to identify challenges in home care services. Phase 2 involved a scoping review of home care frameworks from various countries. In Phase 3, an initial model was created based on previous findings and relevant documents in Iran. In the fourth phase, feedback was gathered from an expert panel selected through purposive sampling, with discussions recorded and concluding at saturation. The feedback was then integrated into the final model. Additionally, in a Delphi study, experts evaluated the model components using a four-point Likert scale, calculating the content validity index (CVI) for each item. A CVI of 79% or higher indicated validity, and continuous feedback led to iterative refinements. RESULTS Following the design of the initial model, an expert panel convened with 15 participants to review the framework. The final model comprises seven key components: leadership and governance, legislative framework, financial framework, human resource management system, information management system, and control and monitoring system. Results from the Delphi study indicated that with a CVI exceeding 80%, this model is deemed a valid framework for delivering home-based care. CONCLUSION This study presents a comprehensive model that serves as a valuable guide for policymakers seeking to implement integrated home care with professional oversight. By doing so, it aims to enhance the quality of care and improve stakeholder satisfaction.
Collapse
Affiliation(s)
- Khorshid Mobasseri
- Department of Geriatric Health, Faculty of Health Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
| | - Shabnam Ghasemyani
- Department of Healthcare Services Management, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran
| | - Rahim Khodayari-Zarnaq
- Department of Health Policy and Management, School of Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran
| | - Ahmad Kousha
- Department of Health Education and Promotion, Faculty of Health Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
| |
Collapse
|
|
4
|
Ren JL, Yang J, Hu W. The global burden of osteoarthritis knee: a secondary data analysis of a population-based study. Clin Rheumatol 2025:10.1007/s10067-025-07347-6. [PMID: 39937200 DOI: 10.1007/s10067-025-07347-6] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/21/2024] [Revised: 12/25/2024] [Accepted: 01/21/2025] [Indexed: 02/13/2025]
Abstract
BACKGROUND Osteoarthritis knee poses a substantial and pervasive global health challenge. METHODS The data was extracted from the Global Burden of Disease 2021 Study database. First, numbers and age-standardized rates (ASRs) of incidence, prevalence, and disability-adjusted life years (DALYs) of osteoarthritis knee were assessed globally and by sub-types in 2021. Subsequently, we employed a linear regression model to analyze the temporal trends from 1990 to 2021. To predict the future burden, we utilized the age-period-cohort model and the Bayesian age-period-cohort model. Furthermore, we conducted a sensitivity analysis using the Autoregressive Integrated Moving Average model and the Exponential Smoothing model. RESULTS In 2021, osteoarthritis knee accounted for 30.85 million incidence cases, 374.74 million prevalence cases, and 12.02 million DALYs cases globally, with ASRs of 353.67, 4294.27, and 137.59, respectively. Females and individuals over 50 years old were identified as high-risk populations, while higher socio-demographic index regions emerged as high-risk areas. From 1990 to 2021, incidence cases rose from 14.13 million to 30.85 million, prevalence cases from 159.80 million to 374.74 million, and DALYs cases from 5.15 million to 12.02 million, accompanied by increases in their respective ASRs. Projections using the APC model predict a continued increase in incidence, prevalence, and DALYs cases for both genders until 2046. Specifically, male incidence cases are projected to increase to 18.45 million and female incidence to 25.60 million. Similarly, male prevalence cases are projected to rise to 235.41 million and female prevalence to 365.97 million. Male DALYs cases are expected to increase to 7.52 million and female DALYs to 11.55 million. The BAPC models also indicate an upward trend in number of cases. CONCLUSION In conclusion, osteoarthritis knee represents a formidable threat to global public health, necessitating the development of proactive and tailored strategic interventions that account for global-specific contexts. Key Points • Females and individuals over 50 years old were identified as high-risk populations. • Higher socio-demographic index regions were identified as high-risk areas. • The disease burden attributable to osteoarthritis knee increased from 1990 to 2019. • The number of deaths and DALYs cases would still increase in the next 25 years.
Collapse
Affiliation(s)
- Jia-Le Ren
- Department of Rheumatology & Immunology, The First Affiliated Hospital of Anhui Medical University, No.218, Ji-Xi Road, Hefei, 230022, China
| | - Junnan Yang
- School of Public Health, BengBu Medical University, 2600 Donghai Avenue, Bengbu, 233030, Anhui, China
| | - Wan Hu
- Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, 230032, Anhui, China.
| |
Collapse
|
|
5
|
Aljahdali AA. Food insecurity and ultra-processed food consumption in the Health and Retirement Study: Cross-sectional analysis. J Nutr Health Aging 2025; 29:100422. [PMID: 39778268 DOI: 10.1016/j.jnha.2024.100422] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/06/2024] [Revised: 11/14/2024] [Accepted: 11/14/2024] [Indexed: 01/11/2025]
Abstract
BACKGROUND Higher ultra-processed foods (UPF), attributed to more than half of daily intake in the US, have been associated with impaired health outcomes. Documented evidence highlights disparities in UPF consumption due to food insecurity, which is a public health challenge among older adults in the US. OBJECTIVES The study examined the link between food insecurity and UPF consumption. The potential of participants' sex, age, and race and Supplemental Nutrition Assistance Program (SNAP) participation in modifying the association were explored. METHOD The analytical sample comprised 6295 US adults, aged 52 - 101 years, enrolled in the longitudinal Health and Retirement Study (HRS), a nationally representative study of aging. Food insecurity was evaluated in the 2013 HRS Health Care and Nutrition Study using the six-item Short Form Food Security Survey Module. Dietary intake was assessed using a food frequency questionnaire, and UPFs, quantified using the NOVA food classification system, were expressed as a percentage of total energy intake. The association between food insecurity and UPFs was examined using linear regression models, adjusted for sociodemographic characteristics. RESULTS The prevalence of food insecurity was 15%. Mean UPFs% (95% confidence intervals) were 49.1 (47.8, 50.3), 48.5 (46.6, 50.4), and 52.3 (50.4, 54.3) among adults with food security, low food security, and very low food security, respectively (P-trend = 0.0156). Race modifies the association between food insecurity and UPFs (P-interaction = 0.0033). A positive linear trend was detected among Whites (P-trend = 0.0036), but an inverse linear trend was found among African Americans (P-trend = 0.0007). There was no evidence for heterogeneity by age, sex, or SNAP participation. CONCLUSION Food insecurity was positively correlated with UPF consumption among adults in the US. Race modifies the association with a positive linear trend among Whites and an inverse linear trend among African Americans. Further efforts are needed to promote healthy aging via improving diet quality among food-insecure older adults.
Collapse
Affiliation(s)
- Abeer A Aljahdali
- Department of Clinical Nutrition, King Abdulaziz University, Jeddah, Saudi Arabia; Department of Nutritional Sciences, University of Michigan, Ann Arbor, MI, United States.
| |
Collapse
|
|
6
|
Rathnayake N, Kannangara W, Abeygunasekara T, De Zoysa W, Palangasinghe D, Lekamwasam S. Burden of caregivers of older people in Sri Lanka: an overlooked concern in the health care system. BMC Geriatr 2025; 25:32. [PMID: 39815204 PMCID: PMC11734462 DOI: 10.1186/s12877-025-05681-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/18/2024] [Accepted: 01/03/2025] [Indexed: 01/18/2025] Open
Abstract
BACKGROUND Caring for older people has become a significant public health concern in Sri Lanka due to the growing aging population. This has placed a heavy burden on family caregivers, particularly those caring for older individuals with multiple chronic conditions. Recognizing this challenge, the present study aimed to evaluate the psychometric properties of the Sinhala version of the 10-item short form of the Burden Scale for Family Caregivers (BSFC-s) and assess caregiver burden and associated factors among caregivers of older people aged over 65 years with multimorbidity. METHODS The BSFC-s was cross-culturally adapted following standard guidelines and administered to consecutively selected 178 family caregivers involved in the long-term care of older patients (aged ≥ 65 years) who were regular attendees of medical and neurology clinics at the National Hospital Galle, Sri Lanka. The validated Sinhala version of the Short Form-36 questionnaire (SF-36) was also administered simultaneously. After two weeks, 60 caregivers were re-assessed using the BSFC-s. The psychometric properties, including reliability and validity, as well as floor and ceiling effects, were evaluated. The final version of the BSFC-s was then administered to 270 informal family caregivers in the Gampaha District, Sri Lanka. RESULTS The study revealed that the internal consistency of the Sinhala version of the BSFC-s, measured by Cronbach's alpha, was 0.90, with item-total correlations ranging from 0.38 to 0.82. The test-retest reliability, assessed using the intra-class correlation coefficient, was 0.99 (95% CI: 0.99-1.00; p < 0.001). Principal component analysis revealed two factors explaining 65.8% of the cumulative variance. BSFC-s scores showed a strong negative correlation with SF-36 scores (r = -0.81, p < 0.001), indicating a good concurrent validity. Neither floor nor ceiling effects were observed. Among the 270 family caregivers, 78.1% reported a high level of burden, while 21.1% reported moderate burden. Caregiver burden was significantly associated with low educational level (p = 0.032), low monthly income (p = 0.041), and unemployment status (p < 0.001) of the caregiver. CONCLUSION The Sinhala version of the BSFC-s demonstrated strong reliability and validity, making it a suitable tool for assessing caregiver burden in Sri Lanka. Most caregivers reported high levels of subjective burden, particularly those with lower socio-demographic status. TRIAL REGISTRATION Not applicable.
Collapse
Affiliation(s)
- Nirmala Rathnayake
- Department of Nursing, Faculty of Allied Health Sciences, University of Ruhuna, Galle, Sri Lanka.
| | - Wedura Kannangara
- Department of Nursing, Faculty of Allied Health Sciences, University of Ruhuna, Galle, Sri Lanka
| | - Thilina Abeygunasekara
- Department of Nursing, Faculty of Allied Health Sciences, University of Ruhuna, Galle, Sri Lanka
| | - Warsha De Zoysa
- Department of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka
| | | | - Sarath Lekamwasam
- Department of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka
| |
Collapse
|
|
7
|
Sato M, Torigoe D, Kinoshita Y, Cyuman M, Toda C, Sato M, Ikeda K, Kadomatsu T, Horiguchi H, Morinaga J, Fukami H, Sugizaki T, Miyata K, Kusaba R, Okadome Y, Matsunaga E, Node K, Oike Y. Long-term intake of Tamogi-take mushroom (Pleurotus cornucopiae) mitigates age-related cardiovascular dysfunction and extends healthy life expectancy. NPJ AGING 2025; 11:1. [PMID: 39779757 PMCID: PMC11711650 DOI: 10.1038/s41514-024-00191-z] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Subscribe] [Scholar Register] [Received: 07/26/2024] [Accepted: 12/20/2024] [Indexed: 01/11/2025]
Abstract
Age-related declines in cardiac function and exercise tolerance interfere with healthy living and decrease healthy life expectancy in older individuals. Tamogi-take mushrooms (Pleurotus cornucopiae) are known to contain high levels of Ergothioneine (EGT), an antioxidant with potential health benefits. In this study, we assessed the possibility that long-term consumption of Tamogi-take mushrooms might attenuate age-related decline in cardiac and vascular endothelial function in mice. We found that long-term intake of Tamogi-take mushrooms significantly maintained cardiac and vascular endothelial function and improved exercise tolerance in mice. Long-term mushroom consumption also increased levels of Nrf2 (Nuclear factor E2-related factor 2) protein in heart tissues and increased translation of HO-1 (Heme Oxygenase 1) proteins, which have antioxidant effects in heart and aortic tissues. Finally, long-term Tamogi-take mushroom consumption inhibited ROS accumulation with aging and reduced expression of inflammatory biomarkers. We conclude that ingestion of Tamogi-take mushrooms could serve as a dietary intervention to promote cardiovascular health, support healthy aging and slow the progression of age-related diseases.
Collapse
Affiliation(s)
- Michio Sato
- Department of Molecular Genetics, Kumamoto University, Kumamoto, Japan
- Center for Metabolic Regulation of Healthy Aging (CMHA), Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
- Department of Cardiovascular Medicine, School of Medicine, Saga University, Saga, Japan
- Division of Kumamoto Mouse Clinic (KMC), Kumamoto University, Kumamoto, Japan
| | - Daisuke Torigoe
- Division of Laboratory Animal Science, Institute of Resource Development and Analysis (IRDA), Kumamoto University, Kumamoto, Japan
| | - Yuya Kinoshita
- Department of Molecular Genetics, Kumamoto University, Kumamoto, Japan
| | - Momoka Cyuman
- Division of Laboratory Animal Science, Institute of Resource Development and Analysis (IRDA), Kumamoto University, Kumamoto, Japan
| | - Chitoku Toda
- Department of Neuroscience for Metabolic Control, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
| | - Masaru Sato
- Laboratory of Biomolecule Analysis, Department of Applied Genomics, Kazusa DNA Research Institute, Chiba, Japan
| | - Kazutaka Ikeda
- Laboratory of Biomolecule Analysis, Department of Applied Genomics, Kazusa DNA Research Institute, Chiba, Japan
- Laboratory of Omics and Informatics, Department of Molecular and Chemical Life Sciences, Graduate School of Life Sciences, Tohoku University, Sendai, Japan
| | | | - Haruki Horiguchi
- Department of Molecular Genetics, Kumamoto University, Kumamoto, Japan
- Center for Metabolic Regulation of Healthy Aging (CMHA), Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
- Department of Aging and Geriatric Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
| | - Jun Morinaga
- Department of Molecular Genetics, Kumamoto University, Kumamoto, Japan
- Department of Disease Genome Epidemiology, Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kumamoto, Japan
| | - Hirotaka Fukami
- Department of Molecular Genetics, Kumamoto University, Kumamoto, Japan
| | - Taichi Sugizaki
- Department of Molecular Genetics, Kumamoto University, Kumamoto, Japan
| | - Keishi Miyata
- Department of Molecular Genetics, Kumamoto University, Kumamoto, Japan
| | - Ryoko Kusaba
- Department of Molecular Genetics, Kumamoto University, Kumamoto, Japan
| | - Yusuke Okadome
- Department of Molecular Genetics, Kumamoto University, Kumamoto, Japan
| | - Eiji Matsunaga
- Department of Molecular Genetics, Kumamoto University, Kumamoto, Japan
| | - Koichi Node
- Department of Cardiovascular Medicine, School of Medicine, Saga University, Saga, Japan
| | - Yuichi Oike
- Department of Molecular Genetics, Kumamoto University, Kumamoto, Japan.
- Center for Metabolic Regulation of Healthy Aging (CMHA), Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
- Division of Laboratory Animal Science, Institute of Resource Development and Analysis (IRDA), Kumamoto University, Kumamoto, Japan.
- Department of Aging and Geriatric Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
| |
Collapse
|
|
8
|
Song K, Zhao Z, Saha A, Kundu J. Receiving financial support and its association with late-age depression: The mediating role of social engagement. Exp Gerontol 2025; 199:112647. [PMID: 39643252 DOI: 10.1016/j.exger.2024.112647] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/11/2024] [Revised: 11/28/2024] [Accepted: 12/03/2024] [Indexed: 12/09/2024]
Abstract
OBJECTIVES Researchers have long been concerned with the association between family financial support and depression in older adults. However, it remains unclear whether social engagement influences the relationship between depression and financial support in later life. Therefore, this study aims to examine the relationship between receiving financial support from family and others and depression among Indian older adults and to also explore the mediating effect of social engagement on this relationship. SUBJECTS AND METHODS Data from the Longitudinal Aging Study in India Wave 1 (2017-2018) was used for the empirical analysis. A total sample of 30,210 older adults aged 60 years and above were selected for the study. The study employs bivariate and binary logistic regression analysis. Further Karlson-Holm-Breen method was adopted for mediation analysis. RESULTS The adjusted prevalence of depression among older adults who did not receive financial support from family or others was nearly 33.8 % (men: 29.8 %, women: 37.4 %), compared to 29.9 % for those who received support (men: 27.6 %, women: 32 %). Older adults who received financial support had 21 % lower odds of depression (AoR: 0.79; 95 % CI: 0.73, 0.84) than those who did not. Additionally, the association between depression and receiving financial support was mediated by social engagement (17.3 %) with the mediating effect being higher among older women (29.3 %) than older men (13.5 %). CONCLUSION The study advances that although financial support plays a significant role in reducing depressive symptoms in older adults, social engagement also serves as an important mediator in this relationship. Enhancing opportunities for social engagement may amplify the protective effects of financial support, offering a more comprehensive approach to addressing mental health challenges among aging populations in India.
Collapse
Affiliation(s)
- Keying Song
- Gdansk University of Physical Education and Sport, Poland, 80-336
| | - Zijian Zhao
- Zhengzhou University, Henan Province, China, 450001.
| | - Amiya Saha
- Department of Family & Generations, International Institute for Population Sciences, Mumbai, 400088, India
| | - Jhumki Kundu
- Centre for Ageing Studies, International Institute for Population Sciences, Mumbai, 400088, India
| |
Collapse
|
|
9
|
Larkin MA, Lucey M. Novel multidisciplinary ambulatory palliative care clinic: staff opinion and job satisfaction. BMJ Support Palliat Care 2024; 14:e3056-e3058. [PMID: 38527784 DOI: 10.1136/spcare-2024-004845] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 02/23/2024] [Accepted: 03/14/2024] [Indexed: 03/27/2024]
Affiliation(s)
- Mary Ann Larkin
- Department of Palliative Medicine, Milford Care Centre, Castletroy, Ireland
- ASPIRE Fellowship, Royal College of Physicians of Ireland, Dublin, Ireland
| | - Michael Lucey
- Department of Palliative Medicine, Milford Care Centre, Castletroy, Ireland
| |
Collapse
|
|
10
|
Elnakeeb M, Hallit S, Fekih-Romdhane F, Shaala RS, Mousa EFS, Khalil MIM. Psychometric properties of an Arabic translation of the resilience scale for older adults. Aging Ment Health 2024; 28:1532-1539. [PMID: 38915233 DOI: 10.1080/13607863.2024.2363360] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 01/12/2024] [Accepted: 05/28/2024] [Indexed: 06/26/2024]
Abstract
OBJECTIVES A significant gap currently exists in the availability of reliable and scientifically rigorous measures for evaluating resilience among older Arabic-speaking populations. The primary objective of this study was to assess the psychometric properties of an Arabic adaptation of the 15-item Resilience Scale of Older Adults (RSOA) in a sample of Arabic-speaking Egyptian older adults. METHOD Using a cross-sectional design and a convenience sample of 539 Egyptian older adults, with 60.7% aged between 65 and 75 years (50.3% females), participants completed an online Google form-based anonymous questionnaire, including sociodemographic information, the RSOA, and the 10-item CD-RISC. To ensure accurate translation, the forward-backward translation method was employed. Confirmatory factor analysis (CFA) and gender invariance in the RSOA were analyzed. McDonald's ω and Cronbach's α were calculated to assess internal consistency. RESULTS The results demonstrate that the Arabic RSOA and its subscales exhibit high internal consistency, with McDonald's ω and Cronbach's α values ranging from 0.83 to 0.93. CFA analysis revealed that the four-factor model fit of RSOA was acceptable. Measurement invariance was supported across genders. Furthermore, both genders exhibited no significant differences in all four RSOA dimensions. Convergent validity was supported by demonstrating that the four RSOA sub-scores and total scores correlated positively and significantly with the 10-item CD-RISC. CONCLUSION While further cross-cultural validation involving other Arab countries and communities is necessary, this study suggests that the Arabic RSOA may be used to measure resilience among broader Arabic-speaking older adults in clinical and research contexts.
Collapse
Affiliation(s)
- Mayar Elnakeeb
- Faculty of Nursing, Alexandria University, Alexandria, Egypt
| | - Souheil Hallit
- School of Medicine and Medical Sciences, Holy Spirit University of Kaslik, Jounieh, Lebanon
- Department of Psychology, College of Humanities, Effat University, Jeddah, Saudi Arabia
- Applied Science Research Center, Applied Science Private University, Amman, Jordan
| | - Feten Fekih-Romdhane
- The Tunisian Center of Early Intervention in Psychosis, Department of Psychiatry 'Ibn Omrane', Razi Hospital, Manouba, Tunisia
- Faculty of Medicine of Tunis, Tunis El Manar University, Tunis, Tunisia
| | | | | | | |
Collapse
|
|
11
|
Hua K, Pan Y, Fang J, Wu H, Hua Y. Integrating social, climate and environmental changes to confront accelerating global aging. BMC Public Health 2024; 24:2838. [PMID: 39407185 PMCID: PMC11481513 DOI: 10.1186/s12889-024-20346-7] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 06/01/2024] [Accepted: 10/09/2024] [Indexed: 10/19/2024] Open
Abstract
INTRODUCTION The global increase in the aging population presents critical challenges for healthcare systems, social security, and economic stability worldwide. Although the studies of the global rate of aging have increased more than four times in the past two decades, few studies have integrated the potential combined effects of socio-economic, climatic, and environmental factors. METHODS We calculated the geographic heterogeneity of aging population growth rates from 218 countries between 1960 and 2022. Public databases were then integrated to assess the impacts of seven global stressors: socio-economic vulnerability, temperature, drought, seasonality, climate extremes, air pollution, and greening vulnerability on growth rates of aging population (a totally 156 countries). Linear regression models were primarily used to test the statistically significant effects of these stressors on the rate of aging, and multiple model inference was then used to test whether the number of stressors exceeding specific thresholds (e.g., > 25, 50, and 75%) was consistently significant in the best models. The importance of stressors and the number of stressors exceeding thresholds was verified using random forest models for countries experiencing different population aging rates. RESULTS Our analysis identified significant heterogeneity in growth rates of aging population globally, with many African countries exhibiting significantly lower aging rates compared with Europe. High socio-economic vulnerability, increased climate risks (such as high temperature and intensive extreme climate), and decreased environmental quality were found to significantly increase growth rates of the aging population (P < 0.05). The positive combined impacts of these stressors were diminished at medium-high levels of stressors (i.e., relative to their maximum levels observed in nature). The number of global stressors exceeding the 25% threshold emerged as an important predictor of global aging rates. Demographic changes in regions with relatively rapid aging (e.g., Africa and Asia) are more sensitive to climate change (e.g., extreme climate and drought) and the number of global stressors, and regions with low to medium rates of aging (e.g., Europe and the Americas) are more sensitive to socio-economic vulnerability and environmental stability (e.g., drought, green fragility and air pollution). CONCLUSIONS Our findings underscore that policy tools or methods must be developed that consider the holistic dimension of the global factor. Further investigations are essential to understand the complex interactions between multiple stressors and their combined effects on global aging.
Collapse
Affiliation(s)
- Kaiyu Hua
- Department of Personnel, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Zhejiang, 311200, China
| | - Yanfang Pan
- Department of Personnel, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Zhejiang, 311200, China
| | - Jinqiong Fang
- Department of Personnel, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Zhejiang, 311200, China
| | - Hao Wu
- College of Oceanography, Hohai University, Nanjing, 210098, China
| | - Ying Hua
- Department of Personnel, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Zhejiang, 311200, China.
| |
Collapse
|
|
12
|
He Q, Lai Z, Peng S, Lin S, Mo G, Zhao X, Wang Z. Postoperative pulmonary complications after major abdominal surgery in elderly patients and its association with patient-controlled analgesia. BMC Geriatr 2024; 24:751. [PMID: 39256677 PMCID: PMC11389354 DOI: 10.1186/s12877-024-05337-y] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/05/2024] [Accepted: 08/27/2024] [Indexed: 09/12/2024] Open
Abstract
OBJECTIVES This study aims to identify the risk factors for postoperative pulmonary complications (PPCs) in elderly patients undergoing major abdominal surgery and to investigate the relationship between patient-controlled analgesia (PCA) and PPCs. DESIGN A retrospective study. METHOD Clinical data and demographic information of elderly patients (aged ≥ 60 years) who underwent upper abdominal surgery at the First Affiliated Hospital of Sun Yat-sen University from 2017 to 2019 were retrospectively collected. Patients with PPCs were identified using the Melbourne Group Scale Version 2 scoring system. A directed acyclic graph was used to identify the potential confounders, and multivariable logistic regression analyses were conducted to identify independent risk factors for PPCs. Propensity score matching was utilized to compare PPC rates between patients with and without PCA, as well as between intravenous PCA (PCIA) and epidural PCA (PCEA) groups. RESULTS A total of 1,467 patients were included, with a PPC rate of 8.7%. Multivariable analysis revealed that PCA was an independent protective factor for PPCs in elderly patients undergoing major abdominal surgery (odds ratio = 0.208, 95% confidence interval = 0.121 to 0.358; P < 0.001). After matching, patients receiving PCA demonstrated a significantly lower overall incidence of PPCs (8.6% vs. 26.3%, P < 0.001), unplanned transfer to the intensive care unit (1.1% vs. 8.4%, P = 0.001), and in-hospital mortality (0.7% vs. 5.3%, P = 0.021) compared to those not receiving PCA. No significant difference in outcomes was observed between patients receiving PCIA or PCEA after matching. CONCLUSION Patient-controlled analgesia, whether administered intravenously or epidurally, is associated with a reduced risk of PPCs in elderly patients undergoing major upper abdominal surgery.
Collapse
Affiliation(s)
- Qiulan He
- Department of Anesthesiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China
| | - Zhenyi Lai
- Department of Anesthesiology, Sun Yat-sen Memorial Hospital, Guangzhou, China
| | - Senyi Peng
- Department of Anesthesiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China
| | - Shiqing Lin
- Department of Anesthesiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China
| | - Guohui Mo
- Department of Anesthesiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China
| | - Xu Zhao
- Department of Anesthesiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China.
| | - Zhongxing Wang
- Department of Anesthesiology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China.
| |
Collapse
|
|
13
|
Chen S, Chen Y, Feng M. Indoor Infrared Sensor Layout Optimization for Elderly Monitoring Based on Fused Genetic Gray Wolf Optimization (FGGWO) Algorithm. SENSORS (BASEL, SWITZERLAND) 2024; 24:5393. [PMID: 39205086 PMCID: PMC11359595 DOI: 10.3390/s24165393] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Received: 06/28/2024] [Revised: 08/15/2024] [Accepted: 08/19/2024] [Indexed: 09/04/2024]
Abstract
With the increasing aging of the global population, the efficiency and accuracy of the elderly monitoring system become crucial. In this paper, a sensor layout optimization method, the Fusion Genetic Gray Wolf Optimization (FGGWO) algorithm, is proposed which utilizes the global search capability of Genetic Algorithm (GA) and the local search capability of Gray Wolf Optimization algorithm (GWO) to improve the efficiency and accuracy of the sensor layout in elderly monitoring systems. It does so by optimizing the indoor infrared sensor layout in the elderly monitoring system to improve the efficiency and coverage of the sensor layout in the elderly monitoring system. Test results show that the FGGWO algorithm is superior to the single optimization algorithm in monitoring coverage, accuracy, and system efficiency. In addition, the algorithm is able to effectively avoid the local optimum problem commonly found in traditional methods and to reduce the number of sensors used, while maintaining high monitoring accuracy. The flexibility and adaptability of the algorithm bode well for its potential application in a wide range of intelligent surveillance scenarios. Future research will explore how deep learning techniques can be integrated into the FGGWO algorithm to further enhance the system's adaptive and real-time response capabilities.
Collapse
Affiliation(s)
- Shuwang Chen
- School of Information Science and Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China;
| | - Yajiang Chen
- School of Information Science and Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, China;
| | - Meng Feng
- Department of Acupuncture Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang 050011, China;
| |
Collapse
|
|
14
|
Vancea A, Iliescu M, Aivaz KA, Popescu MN, Beiu C, Spiru L. Improving Functional Capacities and Well-Being in Older Adults: Strategies in Physical Medicine and Rehabilitation. Cureus 2024; 16:e66254. [PMID: 39238764 PMCID: PMC11375479 DOI: 10.7759/cureus.66254] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 08/05/2024] [Indexed: 09/07/2024] Open
Abstract
As life expectancy continues to increase, improving the quality of life (QoL) for older adults becomes an important issue. This study investigated the impact of a two-week intensive rehabilitation program at the Techirghiol Balneal and Rehabilitation Sanatorium on older adults' QoL, focusing on physical and cognitive function. The study employed a comprehensive geriatric assessment to evaluate the progress of 156 patients over 65 from admission to discharge. We used the Scale for Identifying Fall Risk Factors (STRATIFY) scale to assess the risk of falling, the Visual Analogue Scale (VAS) to assess pain levels, and the Functional Independence Measure (FIM) to assess motor and cognitive abilities. The program included multi-parametric evaluations and personalized treatment plans. Statistical analysis of these data led to the following results: The STRATIFY scale showed a significant improvement in patient functionality and a decrease in the risk of falling during hospitalization, with a mean difference in scores between admission and discharge ranging from 0.141 to 0.372, with a p-value of less than 0.001, confirming the clinical significance of this improvement. The VAS showed a significant reduction in pain or symptom intensity, reflected by a mean decrease of -3.141 between admission and discharge. The FIM recorded a mean increase of 1.436 in patients' motor capacity between admission and discharge, reflecting improved adaptation to daily activities, especially in the areas of self-care, sphincter control, transfer, and locomotion. Social participation and health status were positively influenced, demonstrating the benefits of short-term, intensive rehabilitation. The two-week rehabilitation program significantly improved the QoL of older adult patients. These outcomes suggested that active aging strategies could be effectively integrated into medical and institutional care frameworks, highlighting the necessity for policies that support older adults' involvement in economic and social contexts.
Collapse
Affiliation(s)
- Amalia Vancea
- Physical Medicine and Rehabilitation - Ovidius Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, ROU
| | - Madalina Iliescu
- Physical Medicine and Rehabilitation - Ovidius Faculty of Medicine, Balneal and Rehabilitation Sanatorium of Techirghiol, Techirghiol, ROU
| | - Kamer-Ainur Aivaz
- Economic Sciences, Ovidius Faculty of Economic Science, Constanta, ROU
| | - Marius N Popescu
- Physical Medicine and Rehabilitation - Elias Emergency University Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, ROU
| | - Cristina Beiu
- Oncologic Dermatology - Elias Emergency University Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, ROU
| | - Luiza Spiru
- Geriatrics, Gerontology, Old Age Psychiatry and Longevity Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, ROU
| |
Collapse
|
|
15
|
Galarregui C, Navas-Carretero S, Zulet MA, González-Navarro CJ, Martínez JA, de Cuevillas B, Marcos-Pasero H, Aguilar-Aguilar E, Reglero G, Ramirez de Molina A, Chausa P, Iniesta JM, Hernando ME, Gómez EJ, Garcia-Rudolph A, García-Molina A, Loria-Kohen V, Abete I. Precision nutrition impact on metabolic health and quality of life in aging population after a 3-month intervention: A randomized intervention. J Nutr Health Aging 2024; 28:100289. [PMID: 38865737 DOI: 10.1016/j.jnha.2024.100289] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/24/2024] [Revised: 03/25/2024] [Accepted: 06/04/2024] [Indexed: 06/14/2024]
Abstract
OBJECTIVES Innovative precision dietary procedures are required to promote healthy aging. This study aimed to evaluate the effects of a personalised strategy based on the inclusion of individualised foods and digital tools on overall health status and quality of life within a follow-up of 3 months in older adults with overweight or obesity. METHODS 127 men and women aged between 50 and 80 years with overweight/obesity participated in the study-between January 2020 and September 2020 at the Center for Nutrition Research-University of Navarra and IMDEA-ALIMENTACIÓN-and were randomly assigned to a usual-care group (standard recommendations) or precision group (precision nutrition strategy based on the inclusion of individualised foods and a mobile application). Anthropometry, body fat percentage, biochemical parameters, diet, and quality of life (SF-36 Health Survey) were assessed at baseline and after 3 months. RESULTS Both strategies were found to improve overall metabolic health; however, the precision approach demonstrated significantly better outcomes. The precision strategy reduced body weight at 3 months (-4.3 kg; p < 0.001) with significant improvements in body fat percentage, blood pressure and general metabolic health (glycated haemoglobin; alanine aminotransferase; aspartate aminotransferase; hepatic steatosis index) in comparison with the standard recommendations. The precision approach significantly enhanced the quality of life (SF-36) of individuals, with additional improvements in emotional well-being (p = 0.024) and vitality (p = 0.008). Adherence to the Mediterranean diet was significantly associated with a higher quality of life and vitality. CONCLUSION These results support the benefit of precision nutrition approaches for promoting healthy aging and emotional well-being, enhancing the quality of life in aging populations, during the COVID-19 pandemic.
Collapse
Affiliation(s)
- Cristina Galarregui
- Center for Nutrition Research and Department of Nutrition, Food Sciences and Physiology, Faculty of Pharmacy and Nutrition, University of Navarra, 31008 Pamplona, Spain
| | - Santiago Navas-Carretero
- Center for Nutrition Research and Department of Nutrition, Food Sciences and Physiology, Faculty of Pharmacy and Nutrition, University of Navarra, 31008 Pamplona, Spain; Institute for Health Research (IdiSNA), 31008 Pamplona, Spain; Biomedical Research Centre Network in Physiopathology of Obesity and Nutrition (CIBERobn), Instituto de Salud Carlos III, 28029 Madrid, Spain.
| | - M Angeles Zulet
- Center for Nutrition Research and Department of Nutrition, Food Sciences and Physiology, Faculty of Pharmacy and Nutrition, University of Navarra, 31008 Pamplona, Spain; Institute for Health Research (IdiSNA), 31008 Pamplona, Spain; Biomedical Research Centre Network in Physiopathology of Obesity and Nutrition (CIBERobn), Instituto de Salud Carlos III, 28029 Madrid, Spain
| | - Carlos J González-Navarro
- Center for Nutrition Research and Department of Nutrition, Food Sciences and Physiology, Faculty of Pharmacy and Nutrition, University of Navarra, 31008 Pamplona, Spain
| | - J Alfredo Martínez
- Center for Nutrition Research and Department of Nutrition, Food Sciences and Physiology, Faculty of Pharmacy and Nutrition, University of Navarra, 31008 Pamplona, Spain; Biomedical Research Centre Network in Physiopathology of Obesity and Nutrition (CIBERobn), Instituto de Salud Carlos III, 28029 Madrid, Spain
| | - Begoña de Cuevillas
- Center for Nutrition Research and Department of Nutrition, Food Sciences and Physiology, Faculty of Pharmacy and Nutrition, University of Navarra, 31008 Pamplona, Spain
| | - Helena Marcos-Pasero
- Nutrition and Clinical Trials Unit, GENYAL Platform IMDEA-Food Institute, CEI UAM+CSIC, 28049, Madrid, Spain
| | - Elena Aguilar-Aguilar
- Nutrition and Clinical Trials Unit, GENYAL Platform IMDEA-Food Institute, CEI UAM+CSIC, 28049, Madrid, Spain
| | - Guillermo Reglero
- Nutrition and Clinical Trials Unit, GENYAL Platform IMDEA-Food Institute, CEI UAM+CSIC, 28049, Madrid, Spain; Department of Production and Characterization of Novel Foods, Institute of Food Science Research (CIAL) CEI UAM+CSIC, 28049, Madrid, Spain
| | - Ana Ramirez de Molina
- Molecular Oncology and Nutritional Genomics of Cancer, IMDEA-Food Institute, CEI UAM+CSIC, 28049, Madrid, Spain
| | - Paloma Chausa
- Biomedical Engineering and Telemedicine Centre, ETSI Telecomunicación, Center for Biomedical Technology, Universidad Politécnica de Madrid, 28040 Madrid, Spain
| | - Jose M Iniesta
- Biomedical Engineering and Telemedicine Centre, ETSI Telecomunicación, Center for Biomedical Technology, Universidad Politécnica de Madrid, 28040 Madrid, Spain
| | - M Elena Hernando
- Biomedical Engineering and Telemedicine Centre, ETSI Telecomunicación, Center for Biomedical Technology, Universidad Politécnica de Madrid, 28040 Madrid, Spain; Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
| | - Enrique J Gómez
- Biomedical Engineering and Telemedicine Centre, ETSI Telecomunicación, Center for Biomedical Technology, Universidad Politécnica de Madrid, 28040 Madrid, Spain; Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain
| | - Alejandro Garcia-Rudolph
- Department of Research and Innovation, Institut Guttmann, Institut Universitari De Neurorehabilitació Adscrit a La UAB, Barcelona, Spain; Universitat Autònoma De Barcelona, Bellaterra (Cerdanyola Del Vallès), Spain; Fundació Institut d'Investigació En Ciències De La Salut Germans Trias I Pujol, Barcelona, Spain; Fundació Institut d'Investigació en Ciències de la Salut Germans, Barcelona, Spain
| | - Alberto García-Molina
- Department of Research and Innovation, Institut Guttmann, Institut Universitari De Neurorehabilitació Adscrit a La UAB, Barcelona, Spain; Universitat Autònoma De Barcelona, Bellaterra (Cerdanyola Del Vallès), Spain; Fundació Institut d'Investigació En Ciències De La Salut Germans Trias I Pujol, Barcelona, Spain; Fundació Institut d'Investigació en Ciències de la Salut Germans, Barcelona, Spain
| | - Viviana Loria-Kohen
- Nutrition and Clinical Trials Unit, GENYAL Platform IMDEA-Food Institute, CEI UAM+CSIC, 28049, Madrid, Spain
| | - Itziar Abete
- Center for Nutrition Research and Department of Nutrition, Food Sciences and Physiology, Faculty of Pharmacy and Nutrition, University of Navarra, 31008 Pamplona, Spain; Institute for Health Research (IdiSNA), 31008 Pamplona, Spain; Biomedical Research Centre Network in Physiopathology of Obesity and Nutrition (CIBERobn), Instituto de Salud Carlos III, 28029 Madrid, Spain
| |
Collapse
|
|
16
|
Eldemir K, Eldemir S, Ozkul C, Guclu-Gunduz A. The immediate efficacy of the spinomed orthosis and biofeedback posture orthosis on balance and gait in older people with thoracic hyperkyphosis. Gait Posture 2024; 111:136-142. [PMID: 38691976 DOI: 10.1016/j.gaitpost.2024.04.019] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 10/30/2023] [Revised: 02/26/2024] [Accepted: 04/20/2024] [Indexed: 05/03/2024]
Abstract
BACKGROUND Increased kyphosis is a common condition among older people that may, directly or indirectly, be a risk factor for poor balance and gait. Spinomed and Biofeedback Posture Trainer (BPT) orthoses is an effective treatment approach for hyperkyphosis. This study aimed to compare the immediate effects of the Spinomed and BPT orthoses on balance and gait in the older population. METHODS A total of 52 volunteer older people with hyperkyphosis (kyphosis angle>40°) participated in this study and were randomly allocated into two groups, to either the Spinomed orthosis (n = 26, mean age = 65.50 ± 5.50) or the BPT (n = 26, mean age = 65.38 ± 5.69) orthosis. All participants were asked to wear the orthoses for 1.5 h to get used to them. Balance parameters, which are Postural Stability Test (PST), Limits of Stability (LOS), and Clinical Test of Sensory Integration for Balance (m-CTSIB) were assessed using the Biodex Balance System, while walking parameters were assessed using the G-Walk with and without orthosis. RESULTS The Spinomed had a positive effect on balance parameters (p < 0.05) except for the closed eyes firm surface and the opened eyes foam surface conditions of the m-CTSIB (p > 0.05). BPT had a significant impact on the PST score, LOS, and the closed eyes firm surface condition of the m-CTSIB (p < 0.001). Spinomed had a significant effect on cadence, speed, gait cycle duration, elaborated steps, and symmetry index of pelvic angles (p < 0.05), while the BPT had a significant effect only on step length and rotation symmetry index. No significant difference was detected between the two types of orthoses in the balance and gait parameters (p > 0.05). CONCLUSIONS Spinomed and BPT were both effective in improving balance performance, with similar improvements demonstrated by both orthoses. Additionally, Spinomed may provide significant improvements in cadence, speed, gait cycle duration, elaborated steps, and all symmetry indexes of pelvic angles in the short term.
Collapse
Affiliation(s)
- Kader Eldemir
- Ordu University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Ordu, Türkiye.
| | - Sefa Eldemir
- Sivas Cumhuriyet University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Sivas, Türkiye
| | - Cagla Ozkul
- Gazi University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Ankara, Türkiye
| | - Arzu Guclu-Gunduz
- Gazi University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Ankara, Türkiye
| |
Collapse
|
|
17
|
Huang D, Feng R, Shi M. Does the community service environment affect the willingness of older adults people to socialize for older adults care? Front Public Health 2024; 12:1370808. [PMID: 38864015 PMCID: PMC11165074 DOI: 10.3389/fpubh.2024.1370808] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/15/2024] [Accepted: 05/07/2024] [Indexed: 06/13/2024] Open
Abstract
Population ageing is a significant trend in social development and will remain a fundamental national condition in China for the foreseeable future. Socialized older adults care has become a crucial strategy for China to address population ageing. However, the current levels of acceptance and willingness to seek socialized older adults care among older adults are relatively low. This study focuses on examining how the community environment and services influence older adults people's willingness to engage in social activities related to older adults care. Using data from the China Longitudinal Ageing Social Survey (CLASS) (N = 9,657), this study investigated the impact of the community service environment on older adults people's willingness to participate in social activities related to older adults care through a logit model. The study revealed that 9.15% of older adults (N = 9,657) in China are willing to engage in social activities related to older adults care. Furthermore, the individual characteristics and family support of older adults play a significant role in shaping their willingness to engage in older adults care. The provision of medical services, daily care services, and entertainment venues by the community positively influence older adults people's willingness to participate in social activities related to older adults care (p < 0.01), whereas psychological counselling services have a negative impact (p < 0.01). The impact of community services on older adults people's willingness to engage in social activities related to older adults care varies due to factors such as smoking and chronic diseases. These findings provide valuable insights for improving older adults' social engagement in China.
Collapse
Affiliation(s)
- Denghui Huang
- School of Public Administration, Hohai University, Nanjing, China
| | | | | |
Collapse
|
|
18
|
Gauss T, de Jongh M, Maegele M, Cole E, Bouzat P. Trauma systems in high socioeconomic index countries in 2050. Crit Care 2024; 28:84. [PMID: 38493142 PMCID: PMC10943799 DOI: 10.1186/s13054-024-04863-w] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/31/2023] [Accepted: 03/06/2024] [Indexed: 03/18/2024] Open
Abstract
Considerable political, structural, environmental and epidemiological change will affect high socioeconomic index (SDI) countries over the next 25 years. These changes will impact healthcare provision and consequently trauma systems. This review attempts to anticipate the potential impact on trauma systems and how they could adapt to meet the changing priorities. The first section describes possible epidemiological trajectories. A second section exposes existing governance and funding challenges, how these can be met, and the need to incorporate data and information science into a learning and adaptive trauma system. The last section suggests an international harmonization of trauma education to improve care standards, optimize immediate and long-term patient needs and enhance disaster preparedness and crisis resilience. By demonstrating their capacity for adaptation, trauma systems can play a leading role in the transformation of care systems to tackle future health challenges.
Collapse
Affiliation(s)
- Tobias Gauss
- Division Anesthesia and Critical Care, University Hospital Grenoble Alpes, Grenoble, France.
- Grenoble Institute for Neurosciences, Inserm, U1216, Grenoble Alpes University, Grenoble, France.
| | - Mariska de Jongh
- Network Emergency Care Brabant (NAZB), ETZ Hospital, Tilburg, The Netherlands
| | - Marc Maegele
- Department of Traumatology and Orthopedic Surgery, Cologne-Merheim Medical Center, University Witten-Herdecke, Cologne, Germany
| | - Elaine Cole
- Centre for Trauma Sciences, Blizard Institute, Queen Mary University of London, London, UK
| | - Pierre Bouzat
- Division Anesthesia and Critical Care, University Hospital Grenoble Alpes, Grenoble, France
- Grenoble Institute for Neurosciences, Inserm, U1216, Grenoble Alpes University, Grenoble, France
| |
Collapse
|
|
19
|
Aljahdali AA, Shi Z. Circadian Syndrome Is Associated with Dietary Patterns among Middle-Older Americans: The Health and Retirement Study. Nutrients 2024; 16:760. [PMID: 38542672 PMCID: PMC10975158 DOI: 10.3390/nu16060760] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/22/2024] [Revised: 03/03/2024] [Accepted: 03/05/2024] [Indexed: 04/01/2024] Open
Abstract
Population aging is a global demographic characteristic of the 21st century, and healthy eating is a core component of healthy aging. However, limited evidence is available among older adults for associations between diet quality and circadian syndrome (CircS). Thus, this study examined associations between dietary patterns and CircS among a representative sample of middle-older adults in the US. The sample comprised middle-older adults enrolled in the 2016 core wave of the Health and Retirement Study (HRS) and one of its sub-studies, the 2013 Health Care and Nutrition Study (HCNS). A food frequency questionnaire was used to quantify habitual food intake and identify dietary patterns using a factor analysis. CircS was defined based on the existence of ≥4 components of metabolic syndrome and indicators of sleep disorders and depression. A total of 4253 middle-older adults with a mean age (SD) of 65.4 (10.0) years were included in the study. The prevalence of CircS was 35.9%. Comparing extreme quartiles of the "Prudent Pattern", the odds ratio (95% CI) for CircS was 0.72 (0.55-0.94), and it was 1.47 (1.10-1.95) for the "Western Pattern". The "Western Pattern" was positively associated while the "Prudent Pattern" was inversely associated with the odds of CircS among middle-older adults.
Collapse
Affiliation(s)
- Abeer Ali Aljahdali
- Department of Clinical Nutrition, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia;
- Department of Nutritional Sciences, University of Michigan, Ann Arbor, MI 48109, USA
| | - Zumin Shi
- Human Nutrition Department, College of Health Sciences, QU Health, Qatar University, Doha P.O. Box 2713, Qatar
| |
Collapse
|
|
20
|
Lameirinhas J, Gorostiaga A, Etxeberria I. Defining and assessing psychological frailty in older adults: a scoping review protocol. BMJ Open 2024; 14:e080179. [PMID: 38443084 PMCID: PMC11086467 DOI: 10.1136/bmjopen-2023-080179] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Submit a Manuscript] [Subscribe] [Scholar Register] [Received: 09/22/2023] [Accepted: 02/21/2024] [Indexed: 03/07/2024] Open
Abstract
INTRODUCTION Frailty is widely acknowledged as a multidimensional construct encompassing physical, psychological and social aspects. However, the lack of consensus in defining and operationalising psychological frailty challenges the holistic approach to frailty advocated by health professionals. Consequently, there is a need to develop a comprehensive definition of psychological frailty based on contributions made by experts in the field, primarily existing frailty assessment tools. This scoping review will aim to identify the key psychological variables that are considered in frailty assessment tools used with older adults as well as to analyse how these psychological variables have been operationalised. METHODS AND ANALYSIS The study will be conducted in accordance with recommendations from several methodological frameworks for scoping reviews and will be reported following Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews statement guidelines. A systematic literature search will be performed in the CINAHL, MEDLINE, PsycInfo, Scopus and Web of Science databases, supplemented by a search in Google Scholar and reference lists. The focus will be on studies that describe the development of multicomponent frailty assessment tools including at least one psychological variable. Study selection and data extraction will be independently conducted by three reviewers working in pairs. Data will be presented in tabular form, and the data will be analysed using qualitative content analysis. ETHICS AND DISSEMINATION This study does not require ethical approval since it is based on secondary data analysis. The findings of the review will be disseminated through publication in a peer-reviewed scientific journal and will be presented at conferences and seminars. TRIAL REGISTRATION NUMBER The scoping review was registered in Open Science Framework on 29 March 2022 (https://osf.io/bn24y).
Collapse
Affiliation(s)
- Joanes Lameirinhas
- Clinical and Health Psychology and Research Methodology, University of the Basque Country UPV/EHU, Donostia/San Sebastián, Gipuzkoa, Spain
| | - Arantxa Gorostiaga
- Clinical and Health Psychology and Research Methodology, University of the Basque Country UPV/EHU, Donostia/San Sebastián, Gipuzkoa, Spain
| | - Igone Etxeberria
- Clinical and Health Psychology and Research Methodology, University of the Basque Country UPV/EHU, Donostia/San Sebastián, Gipuzkoa, Spain
| |
Collapse
|
|
21
|
Wendt A, Bielemann RM, Wehrmeister FC, Ricardo LIC, Müller WDA, Machado AKF, da Cruz MF, Bertoldi AD, Brage S, Ekelund U, Tovo-Rodrigues L, Crochemore-Silva I. Is rest-activity rhythm prospectively associated with all-cause mortality in older people regardless of sleep and physical activity level? The 'Como Vai?' Cohort study. PLoS One 2024; 19:e0298031. [PMID: 38363743 PMCID: PMC10871497 DOI: 10.1371/journal.pone.0298031] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/10/2023] [Accepted: 01/16/2024] [Indexed: 02/18/2024] Open
Abstract
OBJECTIVE This study aims to test the association of rest-activity rhythm (intradaily variability and interdaily stability) with all-cause mortality in an older adult cohort in Brazil. It also assesses whether the amount of time spent at each intensity level (i.e., physical activity and nocturnal sleep) interferes with this association. METHODS This cohort study started in 2014 with older adults (≥60 years). We investigated deaths from all causes that occurred until April 2017. Rest-activity rhythm variables were obtained using accelerometry at baseline. Intradaily variability indicates higher rhythm fragmentation, while interdaily stability indicates higher rhythm stability. Cox proportional-hazard models were used to test the associations controlling for confounders. RESULTS Among the 1451 older adults interviewed in 2014, 965 presented valid accelerometry data. During the follow-up period, 80 individuals died. After adjusting the analysis for sociodemographic, smoking, morbidity score, and number of medicines, an increase of one standard deviation in interdaily stability decreased 26% the risk of death. The adjustment for total sleep time and inactivity did not change this association. On the other hand, the association was no longer significant after adjusting for overall physical activity and moderate to vigorous physical activity. CONCLUSION Rest-activity rhythm pattern was not associated with mortality when physical activity was considered, possibly because this pattern could be driven by regular exercise. Promoting physical activity remains a relevant strategy to improve population health.
Collapse
Affiliation(s)
- Andrea Wendt
- Graduate Program in Health Technology, Pontifícia Universidade Católica do Paraná, Curitiba, Brazil
| | - Renata Moraes Bielemann
- Post-Graduation Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil
- School of Nutrition, Federal University of Pelotas, Pelotas, Brazil
| | | | - Luiza I. C. Ricardo
- Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom
| | | | | | | | - Andréa D. Bertoldi
- Post-Graduation Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil
| | - Soren Brage
- Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom
| | - Ulf Ekelund
- Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway
- Department of Chronic diseases, Norwegian Institute of Public Health, Oslo, Norway
| | | | - Inácio Crochemore-Silva
- Post-Graduation Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil
- Post-Graduation Program in Physical Education, Federal University of Pelotas, Pelotas, Brazil
| |
Collapse
|
|
22
|
Mrejen M, Nunes L, Giacomin K. Socioeconomic inequalities in health and healthcare utilization among the elderly in Brazil: results from the 2019 National Health Survey. Public Health 2024; 226:165-172. [PMID: 38071949 DOI: 10.1016/j.puhe.2023.11.015] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 08/18/2023] [Revised: 10/26/2023] [Accepted: 11/08/2023] [Indexed: 01/15/2024]
Abstract
OBJECTIVES To assess socioeconomic-related inequalities in health and healthcare utilization among the elderly in Brazil. STUDY DESIGN Cross-sectional nationally representative household-based survey. METHODS We evaluated the Brazilian National Health Survey data collected in 2019. We computed the prevalence of measures of health conditions and healthcare utilization by age-bracket and markers of socioeconomic status-income, educational attainment, and race/ethnicity-among individuals aged 60 or older. We further employed logistic regression models, adjusted for a wide set of covariates, to estimate the relationship between socioeconomic status and those outcomes. RESULTS Higher-income and more educated individuals exhibit better health conditions compared to their lower-income and less-educated counterparts within each age bracket. Results from regression models showed strong associations with income and educational attainment for most health conditions: health status, physical activity, difficulties with activities of daily living and instrumental activities of daily living, and depression. For most conditions, weaker or no associations with race/ethnicity were found. Individuals in the highest income quintile and that completed higher education also had higher odds of having consulted a physician, while high-income individuals had lower odds of having received emergency care at home. CONCLUSIONS The findings of this study highlight the significant socioeconomic inequalities in the health of the elderly population in Brazil. The substantial and pervasive nature of these inequalities stresses the need for action to address them.
Collapse
Affiliation(s)
- M Mrejen
- Instituto de Estudos para Políticas de Saúde (IEPS), São Paulo, SP, Brazil.
| | - L Nunes
- Insper, São Paulo, SP, Brazil
| | - K Giacomin
- NESPE, FIOCRUZ/UFMG, Belo Horizonte, MG, Brazil
| |
Collapse
|
|
23
|
Trescato I, Roversi C, Vettoretti M, Di Camillo B, Facchinetti A. A model to forecast the two-year variation of subjective wellbeing in the elderly population. BMC Med Inform Decis Mak 2023; 23:253. [PMID: 37940954 PMCID: PMC10634107 DOI: 10.1186/s12911-023-02360-8] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/07/2022] [Accepted: 10/31/2023] [Indexed: 11/10/2023] Open
Abstract
BACKGROUND The ageing global population presents significant public health challenges, especially in relation to the subjective wellbeing of the elderly. In this study, our aim was to investigate the potential for developing a model to forecast the two-year variation of the perceived wellbeing of individuals aged over 50. We also aimed to identify the variables that predict changes in subjective wellbeing, as measured by the CASP-12 scale, over a two-year period. METHODS Data from the European SHARE project were used, specifically the demographic, health, social and financial variables of 9422 subjects. The subjective wellbeing was measured through the CASP-12 scale. The study outcome was defined as binary, i.e., worsening/not worsening of the variation of CASP-12 in 2 years. Logistic regression, logistic regression with LASSO regularisation, and random forest were considered candidate models. Performance was assessed in terms of accuracy in correctly predicting the outcome, Area Under the Curve (AUC), and F1 score. RESULTS The best-performing model was the random forest, achieving an accuracy of 65%, AUC = 0.659, and F1 = 0.710. All models proved to be able to generalise both across subjects and over time. The most predictive variables were the CASP-12 score at baseline, the presence of depression and financial difficulties. CONCLUSIONS While we identify the random forest model as the more suitable, given the similarity of performance, the models based on logistic regression or on logistic regression with LASSO regularisation are also possible options.
Collapse
Affiliation(s)
- Isotta Trescato
- Department of Information Engineering, University of Padova, Padova (PD), Italy
| | - Chiara Roversi
- Department of Information Engineering, University of Padova, Padova (PD), Italy
| | - Martina Vettoretti
- Department of Information Engineering, University of Padova, Padova (PD), Italy
| | - Barbara Di Camillo
- Department of Information Engineering, University of Padova, Padova (PD), Italy
- Department of Comparative Biomedicine and Food Science, University of Padova, Legnaro (PD), Italy
| | - Andrea Facchinetti
- Department of Information Engineering, University of Padova, Padova (PD), Italy.
| |
Collapse
|
|
24
|
Sureshkumar A, Payne MW, Viana R, Hunter SW. The Effect of Advanced Age on Prosthetic Rehabilitation Functional Outcomes in People With Lower Limb Amputations: A Retrospective Chart Audit of Inpatient Admissions. Arch Phys Med Rehabil 2023; 104:1827-1832. [PMID: 37119956 DOI: 10.1016/j.apmr.2023.04.006] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/12/2022] [Revised: 03/31/2023] [Accepted: 04/03/2023] [Indexed: 05/01/2023]
Abstract
OBJECTIVE To evaluate the effect of age on functional outcomes at discharge from prosthetic rehabilitation. DESIGN Retrospective chart audit. SETTING Rehabilitation hospital. PARTICIPANTS Individuals ≥50 years with a transtibial level lower limb amputation (LLA) and above admitted to the inpatient prosthetic rehabilitation program from 2012 to 2019 (n=504). A secondary analysis included a subset of matched participants (n=156). INTERVENTIONS Not applicable. MAIN OUTCOME MEASURES The L-Test of Functional Mobility (L-Test), 2-Minute Walk Test (2MWT), 6-Minute Walk Test (6MWT), and Activities-specific Balance Confidence scale. RESULTS A total of 504 participants (66.7±10.1 years) met the inclusion criteria, 63 participants (84.9±3.7 years) were part of the oldest old group. The sample was stratified into 4 age groups (50-59, 60-69, 70-79, and 80+) for data analysis. The analysis of variances were statistically significant for all outcome measures (P<.001). Post-hoc testing for the L-Test, 2MWT, and 6MWT demonstrated that the oldest old had significantly reduced performance compared with people 50-59 years old (P<.05), but there were no significant differences between the oldest old and the 60-69 [(L-Test, P=.802), (2MWT, P=.570), (6MWT, P=.772)] and 70-79 [(L-Test, P=.148), (2MWT, P=.338), (6MWT, P=.300)] age groups. The oldest old reported significantly lower balance confidence compared with all 3 age groups (P<.05). CONCLUSION The oldest old achieved similar functional mobility outcomes as people 60-79 years, the most common age group of people with an LLA. Advanced age alone should not disqualify individuals from prosthetic rehabilitation.
Collapse
Affiliation(s)
| | - Michael W Payne
- Department of Physical Medicine & Rehabilitation, Parkwood Institute London, Canada; Department of Physical Medicine & Rehabilitation, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada
| | - Ricardo Viana
- Department of Physical Medicine & Rehabilitation, Parkwood Institute London, Canada; Department of Physical Medicine & Rehabilitation, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada
| | - Susan W Hunter
- Faculty of Health Sciences, University of Western Ontario, London, Canada; Department of Physical Medicine & Rehabilitation, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Canada; School of Physical Therapy, University of Western Ontario, London, Canada
| |
Collapse
|
|
25
|
World population aging as a function of period demographic conditions. DEMOGRAPHIC RESEARCH 2023. [DOI: 10.4054/demres.2023.48.13] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 03/12/2023] Open
|
|
26
|
An Overview of Systematic Reviews and Meta-Analyses on the Effect of Medication Interventions Targeting Polypharmacy for Frail Older Adults. J Clin Med 2023; 12:jcm12041379. [PMID: 36835915 PMCID: PMC9960328 DOI: 10.3390/jcm12041379] [Citation(s) in RCA: 7] [Impact Index Per Article: 3.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/21/2022] [Revised: 01/31/2023] [Accepted: 02/04/2023] [Indexed: 02/12/2023] Open
Abstract
Frailty refers to the lack of resilience and a reduction in a person's ability to recover following a health problem, and it is increasingly becoming a challenging aspect of ageing populations. Many older adults are exposed to polypharmacy; i.e., they continue to be on medications without timely re-evaluation. Medication reviews have proven successful in managing polypharmacy in the general population, but there is uncertainty regarding their effect among frail older adults. This overview of published systematic reviews assesses the impact of medication reviews on polypharmacy in frail older adults. Embase was searched from its inception to January 2021 and 28 systematic reviews were identified, out of which 10 were included in the overview. Medication reviews were the most common intervention in 8 out of 10 systematic reviews. The frailty score was reported as an outcome in one systematic review that found no evidence for fundamental pharmacological effects on frailty. Six systematic reviews reported a statistically significant reduction in the number of inappropriately prescribed medications. Four systematic reviews reported on hospital admissions, with two of them reporting a decrease in hospitalisations. The quality assessment was moderate in six and critically low in four of the systematic reviews. We conclude that medication reviews help in reducing the use of inappropriate medications in frail older adults, but that there is insufficient evidence in terms of frailty score and hospital admissions.
Collapse
|
|
27
|
Badawoud AM, AlQadheeb YK, AlZahrani SS, AlGhamdi RA, Alanazi EA, AlFozan SM, AlJafer NS, Asiri IM, Alotaibi FM. The Level of Burden among Caregivers of Patients with Alzheimer's Disease in Saudi Arabia. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 2023; 20:2864. [PMID: 36833560 PMCID: PMC9957410 DOI: 10.3390/ijerph20042864] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Received: 11/14/2022] [Revised: 01/26/2023] [Accepted: 02/01/2023] [Indexed: 06/18/2023]
Abstract
BACKGROUND Caregiver burden is a serious global issue associated with the growing number of older adult patients with Alzheimer's disease (AD). AD patients become more dependent on their caregivers and require assistance with basic daily life activities. This study aims to measure the caregiver burden of informal caregivers of AD patients and to determine their characteristics. In addition, it intends to understand caregiver coping techniques and assess their medication knowledge. METHODS This was a cross-sectional study including 148 informal caregivers mainly recruited by the Saudi Alzheimer's Disease Association (SADA). A four-part study questionnaire was used for data collection in the Arabic Language and included the following: socio-demographic characteristics of AD patients and their caregivers, the 12-item version of the Zarit Burden Interview (ZBI), and adapted questions on coping techniques and medication knowledge. RESULTS A total of 148 caregivers (62% were female) participated in this study, and 79.06% were between 30 and 60 years old. The ZBI average score was 27, indicating a moderate to high burden. Caregivers reported their need for services to improve their quality of life. The medication knowledge was insufficient in most aspects except that more than half were aware of medications' side effects. CONCLUSION Our study revealed that the average burden among informal caregivers of AD patients was moderate-high.
Collapse
Affiliation(s)
- Amal Mohammad. Badawoud
- Department of Pharmacy Practice, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia
| | - Yasmin K. AlQadheeb
- College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia
| | - Shahad S. AlZahrani
- College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia
| | - Razan A. AlGhamdi
- College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia
| | - Elaf A. Alanazi
- College of Clinical Pharmacy, Imam Abdulrahman bin Faisal University, Dammam 31441, Saudi Arabia
| | - Sarah M. AlFozan
- College of Clinical Pharmacy, Imam Abdulrahman bin Faisal University, Dammam 31441, Saudi Arabia
| | - Norah S. AlJafer
- College of Clinical Pharmacy, Imam Abdulrahman bin Faisal University, Dammam 31441, Saudi Arabia
| | - Ibrahim M. Asiri
- Pharmacy Practice Department, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia
| | - Fawaz M. Alotaibi
- Pharmacy Practice Department, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia
| |
Collapse
|
|
28
|
Silva SPCE, Lima AARD, Maciel MJDL, Vasconcelos ECFRD, Silva MMCE, Matos KKC. Violência na velhice: representações sociais elaboradas por pessoas idosas. ESCOLA ANNA NERY 2023. [DOI: 10.1590/2177-9465-ean-2022-0169pt] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/23/2022] Open
Abstract
Resumo Objetivo analisar as representações sociais, para homens e mulheres idosos, acerca da violência na velhice. Método estudo qualitativo baseado no referencial teórico-metodológico das representações sociais. Participaram 40 idosos usuários de Unidades de Saúde da Família em João Pessoa-PB, Brasil, através de entrevistas individuais, organizadas e submetidas ao software IRAMUTEQ, por meio da Classificação Hierárquica Descendente. Resultados a análise apontou cinco classes: Suscetibilidade da pessoa idosa; Prevenção da violência; Responsabilidade social; Expressão social da violência ao idoso; e Violência intrafamiliar. Os dados denotam que as representações da violência são expressas por fatores individuais, comunitários e relacionais/sociais, revelando algumas diferenças de gênero. Conclusões e implicações para a prática percebe-se que o gênero é elemento significativo nas representações. Enquanto os homens indicaram a necessidade de prevenção do fenômeno por meio da educação e responsabilização social, as mulheres apontaram noções subjetivas, incluindo abusos cometidos por familiares, e destacaram a relevância do profissional de saúde para a sua identificação. Tais aspectos apartam singularidades que carecem de um olhar apurado da enfermagem e demais profissionais das equipes da atenção básica, reconhecendo possíveis casos, notificando-os e agindo intersetorialmente para a interrupção das situações verificadas.
Collapse
|
|
29
|
Silva SPCE, Lima AARD, Maciel MJDL, Vasconcelos ECFRD, Silva MMCE, Matos KKC. Violence in old age: social representations elaborated by elderly people. ESCOLA ANNA NERY 2023. [DOI: 10.1590/2177-9465-ean-2022-0169en] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 12/23/2022] Open
Abstract
Abstract Objective to analyze the social representations, for elderly men and women, about violence in old age. Method qualitative study based on the theoretical-methodological framework of social representations. Participants were 40 elderly users of Family Health Units in João Pessoa-PB, Brazil, through individual interviews, organized and submitted to the IRAMUTEQ software, concluded by the Descending Hierarchical Classification. Results the analysis pointed to five classes: Susceptibility of the elderly; Violence prevention; Social responsibility; Social expression of violence against the elderly; and Intrafamily violence. The data show that the representations of violence are expressed by individual, community and relational/social factors, revealing some gender differences. Conclusions and implications for practice it is clear that gender is a significant element in representations. While men indicated the need to prevent the phenomenon through education and social accountability, women pointed to subjective notions, including abuses committed by family members, and highlighting the relevance of the health professional for its identification. Such aspects separate out singularities that lack an accurate look from nursing and other professionals of the primary care teams, recognizing possible cases, notifying them and acting intersectorally to interrupt the situations verified.
Collapse
|
|
30
|
The Influence of Nutritional Status and Sleep Quality on Gustatory Function in Older Adults. MEDICINA (KAUNAS, LITHUANIA) 2022; 59:medicina59010041. [PMID: 36676665 PMCID: PMC9863202 DOI: 10.3390/medicina59010041] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Figures] [Subscribe] [Scholar Register] [Received: 11/14/2022] [Revised: 12/22/2022] [Accepted: 12/23/2022] [Indexed: 12/28/2022]
Abstract
Background and Objectives: Age-related declines in taste function are common. Taste acuity can be affected by nutritional status and sleep quality. This research aims to examine the effect of nutritional status and sleep quality on gustatory function in community-dwelling older adults. Materials and Methods: This cross-sectional study included 119 community-dwelling older adults (50.4% of whom were female). The gustatory function was evaluated using four liquid taste solutions (sweet, bitter, sour, and salty) each at four different concentrations and the Mini Nutritional Assessment (MNA) and Pittsburgh Sleep Quality Index (PSQI) was applied. Additionally, anthropometric measurements were taken. Results: The mean scores on the gustatory test for the sweet, bitter, sour, and salty tastes were 2.11 ± 1.27, 2.12 ± 1.03, 2.28 ± 1.03, and 1.98 ± 1.41, respectively. There were significant differences according to gender, polypharmacy, nutritional status, and sleep quality in identifying sweet tastes (all p < 0.05). It was also found that females and participants without polypharmacy had better scores for bitter tastes. When the gustatory functions were evaluated according to BMI classification, it was determined that underweight participants had a higher sour taste score than the obese ones. Multiple regression analysis revealed that age, MNA score, PSQI score, and gender accounted for a total of 20.4% of the variance in the sweet taste score. Conclusions: Determining the relationship between taste function, nutritional status, and sleep quality in older adults is important in terms of developing new strategies for older adults who have these problems.
Collapse
|
|
31
|
Annear M. Sedentary Behavior and Physical Inactivity in the Asia-Pacific Region: Current Challenges and Emerging Concerns. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 2022; 19:ijerph19159351. [PMID: 35954707 PMCID: PMC9368014 DOI: 10.3390/ijerph19159351] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [MESH Headings] [Track Full Text] [Download PDF] [Subscribe] [Scholar Register] [Received: 07/28/2022] [Accepted: 07/29/2022] [Indexed: 11/28/2022]
Abstract
This editorial sets the scene for our Special Issue on the growing problem of sedentary behavior and physical inactivity in the Asia-Pacific region. In many societies, more than 40% of the adult population and growing numbers of children are insufficiently physically active to safeguard their health. This is contributing to high rates of cardiovascular disease, obesity, and other deleterious health outcomes across the region. The Asia-Pacific is heterogeneous and complex, with diverse social, cultural, and environmental barriers that affect intentions and opportunities for regular physical activity. Recently, the problem has been compounded by the acceleration of population aging, the worsening effects of anthropogenic climate change, and the ongoing COVID-19 pandemic. Without strong leadership, enduring funding support, and innovative interventions that cut across policy and society, we may yet be facing a century of unmitigated expansion of morbidity across the Asia-Pacific.
Collapse
Affiliation(s)
- Michael Annear
- Faculty of Sport Sciences, Waseda University, Tokyo 359-1192, Japan
| |
Collapse
|
|
32
|
Mathur A, Bhardwaj P, Joshi NK, Jain YK, Singh K. Intrinsic capacity of rural elderly in thar desert using world health organization integrated care for older persons screening tool: A pilot study. Indian J Public Health 2022; 66:337-340. [PMID: 36149117 DOI: 10.4103/ijph.ijph_731_22] [Citation(s) in RCA: 6] [Impact Index Per Article: 2.0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/04/2022] Open
Abstract
Integrated Care for Older Persons (ICOPE) screening tool helps to address declines in physical and mental capacities in older people. In India, majority of the older population resides in rural areas and there is a paucity of studies that demonstrates the utility of the ICOPE screening tool in India. Thus, a cross-sectional study was conducted to demonstrate the feasibility of using the World Health Organization ICOPE screening tool in a rural population. Comprehensive geriatric assessment of intrinsic capacity revealed cognitive decline in 31.5% (n = 142) participants, diminished mobility 52.1% (n = 235) participants, eye problems in 49.4% (n = 223) participants, and hearing loss in 68.3% (n = 308) participants. Gender difference was statistically significant with mobility limitation (P = 0.005; χ2 = 7.95) and feeling of pain (P = 0.001; χ2 = 15.64), being more in females than males. This tool seems suitable in identifying the intrinsic capacity of the rural elderly.
Collapse
Affiliation(s)
- Arvind Mathur
- Director, Asian Centre for Medical Education, Research and Innovation, Jodhpur, Rajasthan, India
| | - Pankaj Bhardwaj
- Additional Professor, Community Medicine and Family Medicine, Coordinator, School of Public Health, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
| | - Nitin Kumar Joshi
- Demonstrator, School of Public Health, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
| | - Yogesh Kumar Jain
- Demonstrator, School of Public Health, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
| | - Kuldeep Singh
- Academic Head School of Public Health, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
| |
Collapse
|
|
33
|
Mathur A, Bhardwaj P, Joshi NK, Jain YK, Singh K. Intrinsic capacity of rural elderly in thar desert using world health organization integrated care for older persons screening tool: A pilot study. Indian J Public Health 2022. [PMID: 36149117 DOI: 10.1101/2022.02.04.22270231] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 05/16/2023] Open
Abstract
Integrated Care for Older Persons (ICOPE) screening tool helps to address declines in physical and mental capacities in older people. In India, majority of the older population resides in rural areas and there is a paucity of studies that demonstrates the utility of the ICOPE screening tool in India. Thus, a cross-sectional study was conducted to demonstrate the feasibility of using the World Health Organization ICOPE screening tool in a rural population. Comprehensive geriatric assessment of intrinsic capacity revealed cognitive decline in 31.5% (n = 142) participants, diminished mobility 52.1% (n = 235) participants, eye problems in 49.4% (n = 223) participants, and hearing loss in 68.3% (n = 308) participants. Gender difference was statistically significant with mobility limitation (P = 0.005; χ2 = 7.95) and feeling of pain (P = 0.001; χ2 = 15.64), being more in females than males. This tool seems suitable in identifying the intrinsic capacity of the rural elderly.
Collapse
Affiliation(s)
- Arvind Mathur
- Director, Asian Centre for Medical Education, Research and Innovation, Jodhpur, Rajasthan, India
| | - Pankaj Bhardwaj
- Additional Professor, Community Medicine and Family Medicine, Coordinator, School of Public Health, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
| | - Nitin Kumar Joshi
- Demonstrator, School of Public Health, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
| | - Yogesh Kumar Jain
- Demonstrator, School of Public Health, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
| | - Kuldeep Singh
- Academic Head School of Public Health, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
| |
Collapse
|
|
34
|
Construction Accidents in Spain: Implications for an Aging Workforce. BIOMED RESEARCH INTERNATIONAL 2022; 2022:9952118. [PMID: 35692591 PMCID: PMC9184206 DOI: 10.1155/2022/9952118] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 03/23/2021] [Revised: 03/26/2022] [Accepted: 05/18/2022] [Indexed: 11/19/2022]
Abstract
Construction workers are getting older. In the European Union, the percentage of workers over 50 grew from 24.7% in 2011 to 31.5% in 2018, in Spain from 20.4% to 31.2%. Objective. Identify trends and detailed patterns of accidents of older construction workers compared to other age groups. Data and Method. We analyzed construction accidents in Spain from 2011 to 2018 (N = 455,491). The number of accidents and lost working days (LWD) were broken down by occupation, seniority, company size, temporal variables (weekday, hour), trigger, and body part injured and compared for different age groups. Results. Although older worker had fewer accidents, the consequences of accidents were more serious. Those over 50 years had 84% more lost working days (LWD) than those under 24 years, 48% more than those between 25 and 39 years, and 21% more than those between 40 and 49 years. (1) Occupation: the percentage of accidents grew with age for supervisors, lorry drivers, and bricklayers. (2) Seniority: the least experienced (less than 6 months) and the most experienced (more than 6 years) had the most LWD. (3) Company size: there are 24.5% of accidents in companies of less than four workers. (4) Trigger: older workers suffered more falls, both from height and at the same level. (5) Time: the percentage of accidents in those over 50 was higher on Thursdays and Fridays, in the afternoons from 4 to 7 p.m., and after four hours of work. (6) Injury: this shows the longest absences for shoulder injuries for those over 50 years, with an average of 70 LWD.
Collapse
|
|
35
|
May P, Normand C, Matthews S, Kenny RA, Romero-Ortuno R, Tysinger B. Projecting future health and service use among older people in Ireland: an overview of a dynamic microsimulation model in The Irish Longitudinal Study on Ageing (TILDA). HRB Open Res 2022; 5:21. [PMID: 36262382 PMCID: PMC9554695 DOI: 10.12688/hrbopenres.13525.2] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.7] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 06/07/2022] [Indexed: 10/14/2023] Open
Abstract
Background: Demographic ageing is a population health success story but poses unprecedented policy challenges in the 21st century. Policymakers must prepare health systems, economies and societies for these challenges. Policy choices can be usefully informed by models that evaluate outcomes and trade-offs in advance under different scenarios. Methods: We developed a dynamic demographic-economic microsimulation model for the population aged 50 and over in Ireland: the Irish Future Older Adults Model (IFOAM). Our principal dataset was The Irish Longitudinal Study on Ageing (TILDA). We employed first-order Markovian competing risks models to estimate transition probabilities of TILDA participants to different outcomes: diagnosis of serious diseases, functional limitations, risk-modifying behaviours, health care use and mortality. We combined transition probabilities with the characteristics of the stock population to estimate biennial changes in outcome state. Results: IFOAM projections estimated large annual increases in total deaths, in the number of people living and dying with serious illness and functional impairment, and in demand for hospital care between 2018 and 2040. The most important driver of these increases is the rising absolute number of older people in Ireland as the population ages. The increasing proportion of older old and oldest old citizens is projected to increase the average prevalence of chronic conditions and functional limitations. We deemed internal validity to be good but lacked external benchmarks for validation and corroboration of most outcomes. Conclusion: We have developed and validated a microsimulation model that projects health and related outcomes among older people in Ireland. Future research should address identified policy questions. The model enhances the capacity of researchers and policymakers to quantitatively forecast health and economic dynamics among older people in Ireland, to evaluate ex ante policy responses to these dynamics, and to collaborate internationally on global challenges associated with demographic ageing.
Collapse
Affiliation(s)
- Peter May
- Centre for Health Policy and Management, Trinity College Dublin, 3-4 Foster Place, Dublin, D2, Ireland
- The Irish Longitudinal Study on Ageing, Trinity College Dublin, Pearse Street, Dublin, D2, Ireland
| | - Charles Normand
- Centre for Health Policy and Management, Trinity College Dublin, 3-4 Foster Place, Dublin, D2, Ireland
- Cicely Saunders Institute, King's College London, Denmark Hill, London, SE1 1UL, UK
| | - Soraya Matthews
- Centre for Health Policy and Management, Trinity College Dublin, 3-4 Foster Place, Dublin, D2, Ireland
| | - Rose Anne Kenny
- The Irish Longitudinal Study on Ageing, Trinity College Dublin, Pearse Street, Dublin, D2, Ireland
| | - Roman Romero-Ortuno
- The Irish Longitudinal Study on Ageing, Trinity College Dublin, Pearse Street, Dublin, D2, Ireland
- Global Brain Health Institute, Trinity College Dublin, Lloyd Institute, Dublin, D2, Ireland
| | - Bryan Tysinger
- Leonard D. Schaeffer Center for Health Policy and Economics, University of Southern California, Los Angeles, CA, 90007, USA
| |
Collapse
|
|
36
|
Nava-Gómez L, Calero-Vargas I, Higinio-Rodríguez F, Vázquez-Prieto B, Olivares-Moreno R, Ortiz-Retana J, Aranda P, Hernández-Chan N, Rojas-Piloni G, Alcauter S, López-Hidalgo M. AGING-ASSOCIATED COGNITIVE DECLINE IS REVERSED BY D-SERINE SUPPLEMENTATION. eNeuro 2022; 9:ENEURO.0176-22.2022. [PMID: 35584913 PMCID: PMC9186414 DOI: 10.1523/eneuro.0176-22.2022] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 05/05/2022] [Revised: 05/09/2022] [Accepted: 05/13/2022] [Indexed: 11/21/2022] Open
Abstract
Brain aging is a natural process that involves structural and functional changes that lead to cognitive decline, even in healthy subjects. This detriment has been associated with N-methyl-D-aspartate receptor (NMDAR) hypofunction due to a reduction in the brain levels of D-serine, the endogenous NMDAR co-agonist. However, it is not clear if D-serine supplementation could be used as an intervention to reduce or reverse age-related brain alterations. In the present work, we aimed to analyze the D-serine effect on aging-associated alterations in cellular and large-scale brain systems that could support cognitive flexibility in rats. We found that D-serine supplementation reverts the age-related decline in cognitive flexibility, frontal dendritic spine density, and partially restored large-scale functional connectivity without inducing nephrotoxicity; instead, D-serine restored the thickness of the renal epithelial cells that were affected by age. Our results suggest that D-serine could be used as a therapeutic target to reverse age-related brain alterations.SIGNIFICANT STATEMENTAge-related behavioral changes in cognitive performance occur as a physiological process of aging. Then, it is important to explore possible therapeutics to decrease, retard or reverse aging effects on the brain. NMDA receptor hypofunction contributes to the aging-associated cognitive decline. In the aged brain, there is a reduction in the brain levels of the NMDAR co-agonist, D-Serine. However, it is unclear if chronic D-serine supplementation could revert the age-detriment in brain functions. Our results show that D-serine supplementation reverts the age-associated decrease in cognitive flexibility, functional brain connectivity, and neuronal morphology. Our findings raise the possibility that restoring the brain levels of D-serine could be used as a therapeutic target to recover brain alterations associated with aging.
Collapse
Affiliation(s)
- L Nava-Gómez
- Escuela Nacional de Estudios Superiores, Unidad Juriquilla. UNAM
- Facultad de Medicina. UAQ
| | - I Calero-Vargas
- Escuela Nacional de Estudios Superiores, Unidad Juriquilla. UNAM
- Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
| | - F Higinio-Rodríguez
- Escuela Nacional de Estudios Superiores, Unidad Juriquilla. UNAM
- Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
| | - B Vázquez-Prieto
- Escuela Nacional de Estudios Superiores, Unidad Juriquilla. UNAM
- Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
| | - R Olivares-Moreno
- Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
| | - J Ortiz-Retana
- Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
| | - P Aranda
- Facultad de Ciencias Naturales, UAQ
| | | | - G Rojas-Piloni
- Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
| | - S Alcauter
- Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus Juriquilla, Querétaro, México
| | - M López-Hidalgo
- Escuela Nacional de Estudios Superiores, Unidad Juriquilla. UNAM
| |
Collapse
|
|
37
|
The State of the Evidence about the Family and Community Nurse: A Systematic Review. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 2022; 19:ijerph19074382. [PMID: 35410065 PMCID: PMC8998909 DOI: 10.3390/ijerph19074382] [Citation(s) in RCA: 11] [Impact Index Per Article: 3.7] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Subscribe] [Scholar Register] [Received: 01/27/2022] [Revised: 03/27/2022] [Accepted: 04/02/2022] [Indexed: 02/05/2023]
Abstract
Introduction. The increase in chronic degenerative diseases poses many challenges to the efficacy and sustainability of healthcare systems, establishing the family and community nurse (FCN) who delivers primary care as a strategic role. FCNs, indeed, can embrace the complexity of the current healthcare demand, sustain the ageing of the population, and focus on illness prevention and health promotion, ensuring a continuous and coordinated integration between hospitals and primary care ser. The literature on FCNs is rich but diverse. This study aimed to critically summarise the literature about the FCN, providing an overall view of the recent evidence. Methods. A state-of-art systematic review was performed on PubMed, CINAHL, and Scopus, employing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and checklist to guide the search and reporting. Results. Five interpretative themes emerged from the 90 included articles: clinical practice, core competencies, outcomes, Organisational and educational models, and advanced training program. Conclusions. FCNs can make a major contribution to a population’s health, playing a key role in understanding and responding to patients’ needs. Even if the investment in prevention does not guarantee immediate required strategies and foresight on the part of decisionmakers, it is imperative to invest more political, institutional, and economic resources to support and ensure the FCNs’ competencies and their professional autonomy.
Collapse
|
|
38
|
Shea MK, Korat AVA, Jacques PF, Sebastiani P, Cohen R, LaVertu AE, Booth SL. Leveraging Observational Cohorts to Study Diet and Nutrition in Older Adults: Opportunities and Obstacles. Adv Nutr 2022; 13:1652-1668. [PMID: 35362509 PMCID: PMC9526832 DOI: 10.1093/advances/nmac031] [Citation(s) in RCA: 4] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/02/2021] [Revised: 01/14/2022] [Accepted: 03/25/2022] [Indexed: 01/28/2023] Open
Abstract
By 2060, the number of adults aged ≥65 y is expected to double, and the ≥85 y segment of the population is expected to triple in the United States. US federal nutrition guidance is based on the premise that healthy diets contribute to delaying the onset and progression of many age-related diseases and disability. Yet, little is known about the dietary intakes or nutritional needs across the older adulthood age span. This review aims to identify community-based cohorts that collected information on dietary intake of adults ≥65 y in the United States. Thirty-two cohorts met all inclusion criteria. We summarized information on the cohorts' design, demographics, and diet assessment. We also identified key gaps in the existing databases that, if filled, could enhance their utility to address certain research questions. This review serves as a valuable inventory of cohorts that can be leveraged to answer key questions about the diet and nutritional needs of the oldest old, who represent the fastest growing segment of the population in the United States.
Collapse
Affiliation(s)
| | | | - Paul F Jacques
- USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
| | - Paola Sebastiani
- Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, USA
| | - Rebecca Cohen
- USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
| | - Amy E LaVertu
- Hirsh Health Sciences Library, Tufts University, Boston, MA, USA
| | - Sarah L Booth
- USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, USA
| |
Collapse
|
|
39
|
May P, Normand C, Matthews S, Kenny RA, Romero-Ortuno R, Tysinger B. Projecting future health and service use among older people in Ireland: an overview of a dynamic microsimulation model in The Irish Longitudinal Study on Ageing (TILDA). HRB Open Res 2022; 5:21. [PMID: 36262382 PMCID: PMC9554695 DOI: 10.12688/hrbopenres.13525.1] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Accepted: 03/14/2022] [Indexed: 11/20/2022] Open
Abstract
Background: Demographic ageing is a population health success story but poses unprecedented policy challenges in the 21st century. Policymakers must prepare health systems, economies and societies for these challenges. Policy choices can be usefully informed by models that evaluate outcomes and trade-offs in advance under different scenarios. Methods: We developed a dynamic demographic-economic microsimulation model for the population aged 50 and over in Ireland: the Irish Future Older Adults Model (IFOAM). Our principal dataset was The Irish Longitudinal Study on Ageing (TILDA). We employed first-order Markovian competing risks models to estimate transition probabilities of TILDA participants to different outcomes: diagnosis of serious diseases, functional limitations, risk-modifying behaviours, health care use and mortality. We combined transition probabilities with the characteristics of the stock population to estimate biennial changes in outcome state. Results: IFOAM projections estimated large annual increases in total deaths, in the number of people living and dying with serious illness and functional impairment, and in demand for hospital care between 2018 and 2040. The most important driver of these increases is the rising absolute number of older people in Ireland as the population ages. The increasing proportion of older old and oldest old citizens is projected to increase the average prevalence of chronic conditions and functional limitations. We deemed internal validity to be good but lacked external benchmarks for validation and corroboration of most outcomes. Conclusion: We have developed and validated a microsimulation model that predicts future health and related outcomes among older people in Ireland. Future research should address identified policy questions. The model enhances the capacity of researchers and policymakers to quantitatively forecast future health and economic dynamics among older people in Ireland, to evaluate ex ante policy responses to these dynamics, and to collaborate internationally on global challenges associated with demographic ageing.
Collapse
Affiliation(s)
- Peter May
- Centre for Health Policy and Management, Trinity College Dublin, 3-4 Foster Place, Dublin, D2, Ireland
- The Irish Longitudinal Study on Ageing, Trinity College Dublin, Pearse Street, Dublin, D2, Ireland
| | - Charles Normand
- Centre for Health Policy and Management, Trinity College Dublin, 3-4 Foster Place, Dublin, D2, Ireland
- Cicely Saunders Institute, King's College London, Denmark Hill, London, SE1 1UL, UK
| | - Soraya Matthews
- Centre for Health Policy and Management, Trinity College Dublin, 3-4 Foster Place, Dublin, D2, Ireland
| | - Rose Anne Kenny
- The Irish Longitudinal Study on Ageing, Trinity College Dublin, Pearse Street, Dublin, D2, Ireland
| | - Roman Romero-Ortuno
- The Irish Longitudinal Study on Ageing, Trinity College Dublin, Pearse Street, Dublin, D2, Ireland
- Global Brain Health Institute, Trinity College Dublin, Lloyd Institute, Dublin, D2, Ireland
| | - Bryan Tysinger
- Leonard D. Schaeffer Center for Health Policy and Economics, University of Southern California, Los Angeles, CA, 90007, USA
| |
Collapse
|
|
40
|
Lee JLC, Ho RTH. Creating Exercise Spaces in Parks for Older Adults With Fitness, Rehabilitation, and Play Elements: A Review and Perspective. Gerontol Geriatr Med 2022; 8:23337214221083404. [PMID: 35295288 PMCID: PMC8918966 DOI: 10.1177/23337214221083404] [Citation(s) in RCA: 8] [Impact Index Per Article: 2.7] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/24/2022] [Accepted: 02/02/2022] [Indexed: 12/03/2022] Open
Abstract
Parks usually create a protective playground space for children to perform physical activity like jumping, running, and climbing. Specific spaces have rarely been created for older adults to perform physical activity in public parks. Now that park designs increasingly include outdoor exercise spaces for older adults, yet the important elements or considerations when designing this space remain unclear. Here, we present the emerging importance of and evidence for creating well-designed activity spaces for senior citizens in public parks in the era of population aging.
Collapse
Affiliation(s)
- Janet Lok Chun Lee
- School of Nursing and Health Studies, Hong Kong Metropolitan University, Hong Kong
| | - Rainbow Tin Hung Ho
- Department of Social Work and Social Administration and Centre on Behavioral Health, The University of Hong Kong, Hong Kong
| |
Collapse
|
|
41
|
Bieg T, Gerdenitsch C, Schwaninger I, Kern BMJ, Frauenberger C. Evaluating Active and Assisted Living technologies: Critical methodological reflections based on a longitudinal randomized controlled trial. COMPUTERS IN HUMAN BEHAVIOR 2022. [DOI: 10.1016/j.chb.2022.107249] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/03/2022]
|
|
42
|
Rasekaba TM, Pereira P, Rani G V, Johnson R, McKechnie R, Blackberry I. Exploring Telehealth Readiness in a Resource Limited Setting: Digital and Health Literacy among Older People in Rural India (DAHLIA). Geriatrics (Basel) 2022; 7:28. [PMID: 35314600 PMCID: PMC8938771 DOI: 10.3390/geriatrics7020028] [Citation(s) in RCA: 17] [Impact Index Per Article: 5.7] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 01/31/2022] [Revised: 02/21/2022] [Accepted: 02/25/2022] [Indexed: 11/23/2022] Open
Abstract
An ageing population, disproportionally affecting developing countries, increases demand on healthcare systems. Digital health offers access to healthcare for older people, particularly those residing in rural areas, as is the case for 71% of older adults in India. This research examined technology uptake and digital and health literacy (eHEALS) among a sample of 150 older adults in rural Mysore and Suttur, India. The study utilised mixed-method, with descriptive analysis of quantitative data and thematic analysis of qualitative data. Low rates of digital (11%) and health literacy (3-27% across domains) were identified. Mobile phone ownership was 50%, but very few owned or used a smartphone and less than 10% used the Internet to contact health professionals. Qualitative analysis found low technology usage, driven by limited exposure and confidence in using digital devices. Barriers to usage included poor traditional literacy and physical aspects of ageing like poor vision. Social support from neighbours, family and local primary healthcare staff may enable adoption of digital health. Access to healthcare through digital means among Indian rural older adults needs to consider low rates of both digital and health literacy and leverage the value of support from family and primary healthcare providers.
Collapse
Affiliation(s)
- Tshepo Mokuedi Rasekaba
- John Richards Centre for Rural Ageing Research, La Trobe University, Wodonga, VIC 3689, Australia
| | - Pratibha Pereira
- Department of Geriatric Medicine, JSS Medical College, Mahathma Gandhi Road, Mysore, Mysuru 570004, India
- Clinical Development Services Agency-Centre of Clinical Research Excellence (CDSA-CCRE), JSS Hospital, JSS Academy of Higher Education and Research, Mahathma Gandhi Road, Mysore, Mysuru 570004, India
| | - Vinaya Rani G
- Clinical Development Services Agency-Centre of Clinical Research Excellence (CDSA-CCRE), JSS Hospital, JSS Academy of Higher Education and Research, Mahathma Gandhi Road, Mysore, Mysuru 570004, India
| | - Riya Johnson
- Clinical Development Services Agency-Centre of Clinical Research Excellence (CDSA-CCRE), JSS Hospital, JSS Academy of Higher Education and Research, Mahathma Gandhi Road, Mysore, Mysuru 570004, India
| | - Rebecca McKechnie
- John Richards Centre for Rural Ageing Research, La Trobe University, Wodonga, VIC 3689, Australia
| | - Irene Blackberry
- John Richards Centre for Rural Ageing Research, La Trobe University, Wodonga, VIC 3689, Australia
| |
Collapse
|
|
43
|
Wegener LC, Werner F, Kleyer A, Simon D, Uder M, Janka R, Trattnig S, Welsch GH, Pachowsky ML. Changes in T2 Relaxation Time Mapping of Intervertebral Discs Adjacent to Vertebrae after Kyphoplasty Correlate with the Physical Clinical Outcome of Patients. Diagnostics (Basel) 2022; 12:diagnostics12030605. [PMID: 35328158 PMCID: PMC8946901 DOI: 10.3390/diagnostics12030605] [Citation(s) in RCA: 0] [Impact Index Per Article: 0] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/24/2021] [Revised: 01/20/2022] [Accepted: 02/22/2022] [Indexed: 02/01/2023] Open
Abstract
(1) Background: To assess whether clinical outcomes correlate with tissue changes in the intervertebral discs (IVDs) after kyphoplasty as treatment for vertebral fractures, quantitative MRI was applied. (2) Methods: Quantitative T2 mapping acquired in a 3 T MRI scanner of the thoracolumbar spine was performed in 20 patients two years after kyphoplasty. The IVDs adjacent and nonadjacent to the treated vertebrae were divided into six regions of interest (ROI), which were further categorised into inner (ROI 2–5) and outer (ROI 1 and 6) parts of the IVDs, and the T2 values were analysed. T2 values of adjacent discs were correlated with the items of questionnaires evaluating the clinical outcome (i.e., 36-Item Short Form Survey). (3) Results: Lower T2 values in adjacent IVDs correlated with poorer physical outcome two years after kyphoplasty. The inner part of the IVDs adjacent to treated vertebrae showed statistically significant lower T2 values in segments L2/L3 and L3/L4 compared to nonadjacent ones. Patients with lower T2 values showed more pain and physical limitations in everyday life. (4) Conclusions: Quantitative T2 mapping can detect IVD degeneration in patients after kyphoplasty and correlates with the physical outcome. This technique could help to gain better insights into alterations in tissue composition following kyphoplasty and the consequences for the patients’ quality of life.
Collapse
Affiliation(s)
- Lisa C. Wegener
- Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany;
- Johanna-Etienne Hospital, 41462 Neuss, Germany
| | - Felix Werner
- Department of Internal Medicine 4–Nephrology, University Hospital of Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany;
| | - Arnd Kleyer
- Department of Internal Medicine 3–Rheumatology and Immunology, University Hospital of Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany; (A.K.); (D.S.)
| | - David Simon
- Department of Internal Medicine 3–Rheumatology and Immunology, University Hospital of Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany; (A.K.); (D.S.)
| | - Michael Uder
- Institute of Radiology, University Hospital of Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany; (M.U.); (R.J.)
| | - Rolf Janka
- Institute of Radiology, University Hospital of Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany; (M.U.); (R.J.)
| | - Siegfried Trattnig
- High Field MR Center, Department of Biomedical Imaging and Image Guided Therapy, Medical University of Vienna, 1090 Vienna, Austria;
| | - Goetz H. Welsch
- UKE Athleticum, Department of Trauma and Orthopedic Surgery, University Hospital Hamburg-Eppendorf, University Medical Centre Hamburg-Eppendorf, 20251 Hamburg, Germany;
| | - Milena L. Pachowsky
- Department of Internal Medicine 3–Rheumatology and Immunology, University Hospital of Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany; (A.K.); (D.S.)
- Department of Internal Medicine 3–Rheumatology and Immunology, Department of Trauma and Orthopaedic Surgery, University Hospital of Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany
- Correspondence:
| |
Collapse
|
|
44
|
Govoni M, Danesi F. Do Pomegranate Hydrolyzable Tannins and Their Derived Metabolites Provide Relief in Osteoarthritis? Findings from a Scoping Review. Molecules 2022; 27:1033. [PMID: 35164312 PMCID: PMC8840395 DOI: 10.3390/molecules27031033] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Abstract] [Key Words] [MESH Headings] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 12/30/2021] [Revised: 01/28/2022] [Accepted: 02/01/2022] [Indexed: 11/16/2022] Open
Abstract
Osteoarthritis (OA) is the most common form of arthritis affecting both the elderly and the middle-aged population. Although various therapeutics have been developed to arrest the structural deterioration of cartilage, the current treatments are limited to delay the progress of OA clinically. Therefore, it is pivotal to study new therapeutic agents for chondroprotection and the prevention of cartilage degeneration. Hydrolyzable tannin (HT)-containing foods aroused considerable interest in recent years for their relevant anti-inflammatory effects. The focus of this scoping review is to provide an overview of the evidence of the therapeutic potential of HTs and their metabolites in preventing or alleviating the course of OA. A broad search of PubMed and Scopus databases on this topic resulted in 156 articles. After the exclusion of reviews and not relevant records, 31 articles were retrieved. Although only some papers did not consider the biotransformation of HTs, most recent studies also have investigated the effect of HT metabolites. Further larger clinical trials, with an in-deep analysis of HT metabolization, are still needed to unravel the potential benefits of these compounds in OA, paving the way towards the development of a dietary strategy for the improvement of pro-inflammatory cytokine-induced chondrocyte dysfunctions and injuries.
Collapse
Affiliation(s)
- Marco Govoni
- Reconstructive Orthopedic Surgery and Innovative Techniques—Musculoskeletal Tissue Bank, IRCCS Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, 40136 Bologna, Italy;
| | - Francesca Danesi
- Human Nutrition Unit, Department of Agricultural and Food Sciences (DISTAL), University of Bologna, Piazza Goidanich 60, 47521 Cesena, Italy
| |
Collapse
|
|
45
|
Liu H, Jiao J, Zhu M, Wen X, Jin J, Wang H, Lv D, Zhao S, Sun X, Wu X, Xu T. Nutritional Status According to the Short-Form Mini Nutritional Assessment (MNA-SF) and Clinical Characteristics as Predictors of Length of Stay, Mortality, and Readmissions Among Older Inpatients in China: A National Study. Front Nutr 2022; 9:815578. [PMID: 35145987 PMCID: PMC8822231 DOI: 10.3389/fnut.2022.815578] [Citation(s) in RCA: 17] [Impact Index Per Article: 5.7] [Reference Citation Analysis] [Abstract] [Track Full Text] [Download PDF] [Journal Information] [Subscribe] [Scholar Register] [Received: 11/15/2021] [Accepted: 01/03/2022] [Indexed: 12/13/2022] Open
Abstract
Background Studies are scarce in China that explore the association of nutritional status, measured using the Short-Form Mini Nutritional Assessment (MNA-SF) and biochemical data, on adverse clinical outcomes among older inpatients. In this study, we aimed to determine the prevalence of malnutrition in tertiary hospitals of China and the associations between malnutrition and adverse clinical outcomes. Methods This prospective study involved 5,516 older inpatients (mean age 72.47 ± 5.77 years) hospitalized in tertiary hospitals between October 2018 and February 2019. The tertiary hospitals refer to the hospital with more than 500 beds and can provide complex medical care services. The MNA-SF was used to assess nutritional status. Multiple logistic regression and negative binomial regression were used to analyze the relationship between nutritional parameters and risk of hospital length of stay (LoS), mortality, and rehospitalization. Results We found that 46.19% of hospitalized patients had malnutrition or malnutrition risk, according to the MNA-SF. Death occurred in 3.45% of patients. MNA-SF scores 0–7 (odds ratio [OR] 5.738, 95% confidence interval [CI] 3.473 to 9.48) were associated with a six-fold higher likelihood of death, and scores 8–11 (OR 3.283, 95% CI 2.126–5.069) with a three-fold higher likelihood of death, compared with MNA-SF scores 12–14 in the logistic regression model, after adjusting for potential confounders. A low MNA-SF score of 0–7 (regression coefficient 0.2807, 95% CI 0.0294–0.5320; P < 0.05) and a score of 8–11 (0.2574, 95% CI 0.0863–0.4285; P < 0.01) was associated with a significantly higher (28.07 and 25.74%, respectively) likelihood of increased LoS, compared with MNA-SF score 12–14. MNA-SF scores 0–7 (OR 1.393, 95% CI 1.052–1.843) and 8–11 (OR 1.356, 95% CI 1.124–1.636) were associated with a nearly 1.5-fold higher likelihood of 90-day readmission compared with MNA-SF scores 12–14 in the logistic regression model. Moreover, hemoglobin level, female sex, education level, former smoking, BMI 24–27.9 kg/m2, age 75 years and above, and current alcohol consumption were the main factors influencing clinical outcomes in this population. Conclusions Malnutrition increases the risk of hospital LoS, mortality, and 90-day readmission. The use of nutritional assessment tools in all hospitalized patients in China is needed. The MNA-SF combined with hemoglobin level may be used to identify older inpatients with a high risk of adverse clinical outcomes. These findings may have important implications for the planning of hospital services.
Collapse
Affiliation(s)
- Hongpeng Liu
- Department of Nursing, Chinese Academy of Medical Sciences—Peking Union Medical College, Peking Union Medical College Hospital (Dongdan Campus), Beijing, China
| | - Jing Jiao
- Department of Nursing, Chinese Academy of Medical Sciences—Peking Union Medical College, Peking Union Medical College Hospital (Dongdan Campus), Beijing, China
- *Correspondence: Jing Jiao
| | - Minglei Zhu
- Department of Geriatrics, Chinese Academy of Medical Sciences—Peking Union Medical College, Peking Union Medical College Hospital (Dongdan Campus), Beijing, China
| | - Xianxiu Wen
- Department of Nursing, Sichuan Provincial People's Hospital, Chengdu, China
| | - Jingfen Jin
- Department of Nursing, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, China
| | - Hui Wang
- Department of Nursing, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China
| | - Dongmei Lv
- Department of Nursing, The Second Affiliated Hospital of Haerbin Medical University, Haerbin, China
| | - Shengxiu Zhao
- Department of Nursing, Qinghai Provincial People's Hospital, Xining, China
| | - Xiang Sun
- Department of Nursing, Chinese Academy of Medical Sciences—Peking Union Medical College, Peking Union Medical College Hospital (Dongdan Campus), Beijing, China
| | - Xinjuan Wu
- Department of Nursing, Chinese Academy of Medical Sciences—Peking Union Medical College, Peking Union Medical College Hospital (Dongdan Campus), Beijing, China
- Xinjuan Wu
| | - Tao Xu
- Department of Epidemiology and Statistics, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences and School of Basic Medicine, Beijing, China
- Tao Xu
| |
Collapse
|
|
46
|
Arshad F, MM S, Paplikar A, Rajendran S, Kalkonde Y, Alladi S. Vascular cognitive impairment in India: Challenges and opportunities for prevention and treatment. CEREBRAL CIRCULATION - COGNITION AND BEHAVIOR 2021; 3:100034. [PMID: 36324418 PMCID: PMC9616277 DOI: 10.1016/j.cccb.2021.100034] [Citation(s) in RCA: 2] [Impact Index Per Article: 0.5] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Subscribe] [Scholar Register] [Received: 07/02/2021] [Revised: 10/22/2021] [Accepted: 11/23/2021] [Indexed: 06/16/2023]
Abstract
The burden of vascular contribution to cognitive impairment and dementia is substantially high in India. There are approximately 5.3 million dementia patients in India and nearly 40% are estimated to be due to vascular dementia. Several factors pose unique challenges to reducing the burden of vascular dementia and vascular cognitive impairment (VCI) in India. Wide heterogeneity in vascular risk factor profile, diversity in socioeconomic, ethnic and dietary factors, as well as regional and rural-urban differences impact uniform implementation of preventive and therapeutic strategies. There is limited evidence on the natural history of vascular disease from longitudinal cohorts in India. Additionally, the lack of advanced brain imaging and genetic information pose challenges to understanding pathophysiology and treatment response to VCI in India. Efforts are now being made to implement programmes to reduce cardiovascular risk and VCI at the population level. Cognitive and functional measures appropriate to the diverse linguistic and educational context have been developed to diagnose VCI across India. Multicentric clinical and research cohorts of stroke are also being established. Filling research gaps and developing intervention strategies for the Indian context are crucial to address the growing burden of VCI.
Collapse
Affiliation(s)
- Faheem Arshad
- Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, India
| | - Samim MM
- Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, India
| | - Avanthi Paplikar
- Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, India
| | - Srijithesh Rajendran
- Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, India
| | | | - Suvarna Alladi
- Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, India
| |
Collapse
|
|
47
|
Abstract
Purpose
Recent public health policy emphasizes the achievement of healthy aging as average life expectancy increases worldwide. Evidence for healthy aging from low- and middle-income countries (LMIC) is limited. The purpose of this paper is to assess the prospects of healthy aging and its associated factors in the Indian context.
Design/methodology/approach
The study was based on a national-level panel survey, the Indian Human Development Survey (IHDS) conducted in 2004-05 and 2011-12. The analytical sample consists of 10,218 elderly individuals who were 60 years old and above at the baseline. Change in health status was assessed based on disability and disease incidence at the follow-up. A generalized estimating equation (GEE) model was performed to assess health status change.
Findings
Increasing age was a risk factor for all dimensions of health outcomes. Elderly from the lowest wealth quintiles were more likely to lose health due to short-term morbidity, whereas the highest wealth quintiles were more likely to lose health due to long-term and multi-morbidity, indicating evidence for the presence of the “disease of affluence”. Social capital, such as living in a joint family acted as a protective factor against health risks.
Originality/value
With the results showing the evidence of the “disease of affluence” and “disease of poverty” in different health outcomes, there should be a health policy focus that copes with undergoing epidemiological transition. It is also important to pay attention to health-protecting factors such as social and familial support to achieve healthy aging.
Collapse
|
|
48
|
Zolfaghari S, Khodabandehloo E, Riboni D. TraMiner: Vision-Based Analysis of Locomotion Traces for Cognitive Assessment in Smart-Homes. Cognit Comput 2021; 14:1549-1570. [PMID: 33552305 PMCID: PMC7851509 DOI: 10.1007/s12559-020-09816-3] [Citation(s) in RCA: 5] [Impact Index Per Article: 1.3] [Reference Citation Analysis] [Abstract] [Key Words] [Grants] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 09/03/2020] [Accepted: 12/29/2020] [Indexed: 11/29/2022]
Abstract
The rapid increase in the senior population is posing serious challenges to national healthcare systems. Hence, innovative tools are needed to early detect health issues, including cognitive decline. Several clinical studies show that it is possible to identify cognitive impairment based on the locomotion patterns of the elderly. In this work, we investigate the use of sensor data and deep learning to recognize those patterns in instrumented smart-homes. In order to get rid of the noise introduced by indoor constraints and activity execution, we introduce novel visual feature extraction methods for locomotion data. Our solution relies on locomotion trace segmentation, image-based extraction of salient features from locomotion segments, and vision-based deep learning. We carried out extensive experiments with a large dataset acquired in a smart-home test bed from 153 seniors, including people with cognitive diseases. Results show that our system can accurately recognize the cognitive status of the senior, reaching a macro-\documentclass[12pt]{minimal}
\usepackage{amsmath}
\usepackage{wasysym}
\usepackage{amsfonts}
\usepackage{amssymb}
\usepackage{amsbsy}
\usepackage{mathrsfs}
\usepackage{upgreek}
\setlength{\oddsidemargin}{-69pt}
\begin{document}$$F_1$$\end{document}F1 score of 0.873 for the three categories that we target: cognitive health, mild cognitive impairment, and dementia. Moreover, an experimental comparison shows that our system outperforms state-of-the-art methods.
Collapse
Affiliation(s)
- Samaneh Zolfaghari
- Department of Mathematics and Computer Science, University of Cagliari, Cagliari, Italy
| | - Elham Khodabandehloo
- Department of Geo-spatial Information Systems, K. N. Toosi University of Technology, Tehran, Iran
| | - Daniele Riboni
- Department of Mathematics and Computer Science, University of Cagliari, Cagliari, Italy
| |
Collapse
|
|
49
|
Kudsi O, Gokcal F, Bou-Ayash N. Robotic inguinal hernia repair in patients aged eighty and older. INTERNATIONAL JOURNAL OF ABDOMINAL WALL AND HERNIA SURGERY 2021. [DOI: 10.4103/ijawhs.ijawhs_38_20] [Citation(s) in RCA: 1] [Impact Index Per Article: 0.3] [Reference Citation Analysis] [Track Full Text] [Journal Information] [Subscribe] [Scholar Register] [Indexed: 11/04/2022] Open
|
|
50
|
Gbeasor-Komlanvi FA, Tchankoni MK, Bakoubayi AW, Lokossou MY, Sadio A, Zida-Compaore WIC, Djibril M, Belo M, Agbonon A, Ekouevi DK. Predictors of three-month mortality among hospitalized older adults in Togo. BMC Geriatr 2020; 20:507. [PMID: 33243161 PMCID: PMC7690011 DOI: 10.1186/s12877-020-01907-y] [Citation(s) in RCA: 6] [Impact Index Per Article: 1.2] [Reference Citation Analysis] [Abstract] [Key Words] [Track Full Text] [Download PDF] [Figures] [Journal Information] [Subscribe] [Scholar Register] [Received: 07/04/2020] [Accepted: 11/17/2020] [Indexed: 12/26/2022] Open
Abstract
Background Assessing hospital mortality and its predictors is important as some of these can be prevented through appropriate interventions. Few studies have reported hospital mortality data among older adults in sub-Saharan Africa. The objective of this study was to assess the mortality and associated factors among hospitalized older adults in Togo. Methods We conducted a prospective cohort study from February 2018 to September 2019 among patients ≥50 years admitted in medical and surgical services of six hospitals in Togo. Data were recorded during hospitalization and through telephone follow-up survey within 90 days after admission. The main outcome was all-cause mortality at 3 months. Survival curves were estimated using the Kaplan-Meier method and Cox regression analyses were performed to assess predictors of mortality. Results The median age of the 650 older adults included in the study period was 61 years, IQR: [55–70] and at least one comorbidity was identified in 59.7% of them. The all-cause mortality rate of 17.2% (95%CI: 14.4–20.4) and the majority of death (93.7%) occurred in hospital. Overall survival rate was 85.5 and 82.8% after 30 and 90 days of follow-up, respectively. Factors associated with 3-month mortality were the hospital level in the health pyramid, hospitalization service, length of stay, functional impairment, depression and malignant diseases. Conclusion Togolese health system needs to adjust its response to an aging population in order to provide the most effective care. Supplementary Information The online version contains supplementary material available at 10.1186/s12877-020-01907-y.
Collapse
Affiliation(s)
- Fifonsi Adjidossi Gbeasor-Komlanvi
- Département de Santé Publique, Université de Lomé, Faculté des Sciences de la Santé, Lomé, Togo. .,Centre Africain de Recherche en Epidémiologie et en Santé Publique, Lomé, Togo.
| | | | | | | | - Arnold Sadio
- Département de Santé Publique, Université de Lomé, Faculté des Sciences de la Santé, Lomé, Togo.,Centre Africain de Recherche en Epidémiologie et en Santé Publique, Lomé, Togo
| | | | - Mohaman Djibril
- Département de Santé Publique, Université de Lomé, Faculté des Sciences de la Santé, Lomé, Togo.,Centre Hospitalier Universitaire Sylvanus Olympio, Pavillon Militaire, Lomé, Togo
| | - Mofou Belo
- Département de Santé Publique, Université de Lomé, Faculté des Sciences de la Santé, Lomé, Togo.,Programme National de Lutte contre les Maladies Chroniques, Lomé, Togo
| | - Amegnona Agbonon
- Université de Lomé, Laboratoire de Physiologie-Pharmacologie, Lomé, Togo
| | - Didier Koumavi Ekouevi
- Département de Santé Publique, Université de Lomé, Faculté des Sciences de la Santé, Lomé, Togo.,Centre Africain de Recherche en Epidémiologie et en Santé Publique, Lomé, Togo
| |
Collapse
|