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Ocular drug delivery systems: An overview
Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra, Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, Kansas City, Missouri-64108, United States
Author contributions: Patel A and Cholkar K contributed equally to this paper; all the authors wrote the manuscript.
Correspondence to: Ashim K Mitra, PhD, Professor, Chairman, Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, 2464 Charlotte Street, Kansas City, Missouri-64108, United States. mitraa@umkc.edu
Telephone: +1-816-2351615 Fax: +1-816-2355779
Received: December 25, 2012
Revised: March 21, 2013
Accepted: April 3, 2013
Published online: June 9, 2013
Processing time: 162 Days and 0.9 Hours
Revised: March 21, 2013
Accepted: April 3, 2013
Published online: June 9, 2013
Processing time: 162 Days and 0.9 Hours
Core Tip
Core tip: Drug delivery to targeted ocular tissues has been a major challenge to ocular scientist, for decades. Current review intends to summarize the existing conventional formulations for ocular delivery and their advancements followed by current nanotechnology based formulation developments. Also, recent developments with other ocular drug delivery strategies employing in situ gels, implants, contact lens and microneedles have been discussed.