Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Pharmacol. Jul 19, 2024; 13(1): 96477
Published online Jul 19, 2024. doi: 10.5497/wjp.v13.i1.96477
Natural isothiocyanates of the genus Capparis as potential agonists of apoptosis and antitumor agents: Mechanisms and implications
Nabil Eid, Payal Bhatnagar
Nabil Eid, Department of Anatomy, Division of Human Biology, School of Medicine, International Medical University, Kuala Lumpur 57000, Malaysia
Payal Bhatnagar, Department of Pharmaceutical Technology, School of Pharmacy, International Medical University, Kuala Lumpur 57000, Malaysia
Author contributions: Eid N and Bhatnagar P wrote and revised the manuscript; all authors read and approved the final draft.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Nabil Eid, Doctor, MD, PhD, Academic Editor, Affiliate Associate Professor, Assistant Professor, Research Scientist, Senior Lecturer, Senior Scientist, Teaching Assistant, Department of Anatomy, Division of Human Biology, School of Medicine, International Medical University, Bukit Jalil, Kuala Lumpur 57000, Malaysia. nabilsaleheid@imu.edu.my
Received: May 7, 2024
Revised: July 1, 2024
Accepted: July 10, 2024
Published online: July 19, 2024
Processing time: 72 Days and 14.2 Hours
Abstract

In this editorial, we comment on a recent publication, which highlights the important findings from the study, including the antitumor and anti-inflammatory effects of isothiocyanates, their underlying mechanisms, and implications. Additionally, a related perspective is discussed.

Keywords: Cancer; Isothiocyanates; Genus Capparis; Apoptosis; Autophagy; Inflammation; GC/MS analysis

Core Tip: A growing body of evidence indicates that isothiocyanates derived from natural products possess anticancer and anti-inflammatory properties. This editorial discusses the mechanisms underlying the tumor-suppressing effects of isothiocyanates derived from the genus Capparis, their implications, and a related perspective.