Fydrych J, Hughes AP, Abuhasna S, Mekonen E. Pericarditis following COVID-19 vaccination: Two case reports. World J Clin Infect Dis 2022; 12(1): 33-40 [DOI: 10.5495/wjcid.v12.i1.33]
Corresponding Author of This Article
Justyna Fydrych, PharmD, Pharmacist, Department of Pharmacy, Advocate Trinity Hospital, 2320 E 93rd St, Chicago, IL 60617, United States. jfydry2@gmail.com
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Infect Dis. Apr 26, 2022; 12(1): 33-40 Published online Apr 26, 2022. doi: 10.5495/wjcid.v12.i1.33
Pericarditis following COVID-19 vaccination: Two case reports
Justyna Fydrych, Amanda Paige Hughes, Said Abuhasna, Endale Mekonen
Justyna Fydrych, Department of Pharmacy, Advocate Trinity Hospital, Chicago, IL 60617, United States
Amanda Paige Hughes, Department of Pharmacy, Advocate Aurora Health, Chicago, IL 60617, United States
Said Abuhasna, Department of Critical Care, Advocate Trinity Hospital, Chicago, IL 60617, United States
Endale Mekonen, Department of Infectious Disease, Advocate Trinity Hospital, Chicago, IL 60617, United States
Author contributions: Fydrych J and Hughes AP contributed equally to data collection, research, and manuscript development; Abuhasna S and Mekonen E contributed equally to patient care, interpretation of diagnostics and manuscript review; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patients for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to report.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016). The manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Justyna Fydrych, PharmD, Pharmacist, Department of Pharmacy, Advocate Trinity Hospital, 2320 E 93rd St, Chicago, IL 60617, United States. jfydry2@gmail.com
Received: July 2, 2021 Peer-review started: July 2, 2021 First decision: October 18, 2021 Revised: November 13, 2021 Accepted: January 25, 2022 Article in press: January 25, 2022 Published online: April 26, 2022 Processing time: 297 Days and 7.4 Hours
Core Tip
Core Tip: Coronavirus disease 2019 (COVID-19) manifests with primarily respiratory symptoms and less commonly with cardiac involvement. Myocarditis and pericarditis have been reported in a variety of live and attenuated vaccines. However, to our knowledge, there are no published cases associated with COVID-19 vaccination as of October 2021. We present two cases of pericarditis following COVID-19 vaccination. Both patients were treated with colchicine and non-steroidal anti-inflammatory agents but with varying degrees of invasive work-up. The first patient had emergent cardiac catheterization, while the second patient underwent computed tomographic angiography of the coronary arteries. Neither patient required intervention, thus questioning the necessity of cardiac catheterization.
