Bastos Limeira CB, Veras CM, Lima Paiva JHHG, e Neves MSS, Teles de Carvalho TM, de Assunção Ferreira NS, Mont`Alverne Pierre AM, Brasil IRC. Liver transplantation in patients with SARS-CoV-2: Two case reports. World J Clin Infect Dis 2021; 11(1): 27-34 [DOI: 10.5495/wjcid.v11.i1.27 ]
Corresponding Author of This Article
José Hicaro Hellano Gonçalves Lima Paiva, UECE, Uece, Valdetario mota 1121, FORTALEZA 60175742, Ceara, Brazil. hellanohicaro@gmail.com
Research Domain of This Article
Infectious Diseases
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Infect Dis. Jan 15, 2021; 11(1): 27-34 Published online Jan 15, 2021. doi: 10.5495/wjcid.v11.i1.27
Liver transplantation in patients with SARS-CoV-2: Two case reports
Camilla Bezerra Bastos Limeira, Camila Monteiro Veras, José Hicaro Hellano Gonçalves Lima Paiva, Marina Seixas Studart e Neves, Themístocles Mesquita Teles de Carvalho, Natália Stefani de Assunção Ferreira, Alessandra Maria Mont`Alverne Pierre, Ivelise Regina Canito Brasil
Camilla Bezerra Bastos Limeira, Camila Monteiro Veras, Marina Seixas Studart e Neves, Themístocles Mesquita Teles de Carvalho, Alessandra Maria Mont`Alverne Pierre, Ivelise Regina Canito Brasil, Transplantation Division, Hospital Geral de Fortaleza, FORTALEZA 60175742, CE, Brazil
José Hicaro Hellano Gonçalves Lima Paiva, Natália Stefani de Assunção Ferreira, UECE, Uece, FORTALEZA 60175742, Ceara, Brazil
Author contributions: Veras CM and de Assunção Ferreira NS contributed to data collection; Lima Paiva JHHG, Teles de Carvalho TM and Bastos Limeira CB contributed to the drafting of the manuscript and the creation of tables and figure; e Neves MSS, Mont`Alverne Pierre AM and Brasil IRC critically revised and approved the version to be published; all authors have read and approved the manuscript.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: José Hicaro Hellano Gonçalves Lima Paiva, UECE, Uece, Valdetario mota 1121, FORTALEZA 60175742, Ceara, Brazil. hellanohicaro@gmail.com
Received: September 10, 2020 Peer-review started: September 10, 2020 First decision: October 21, 2020 Revised: November 7, 2020 Accepted: November 29, 2020 Article in press: November 29, 2020 Published online: January 15, 2021 Processing time: 125 Days and 1.4 Hours
Core Tip
Core Tip: Coronavirus disease 2019 (COVID-19), caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its consequences have resulted in high rates of morbidity and mortality worldwide in the first half of this year. This infection shows worse outcomes in certain at-risk populations, including those with cirrhosis of any etiology. Most patients with decompensated cirrhosis have poor quality of life and a high chance of progressing to death if they have high prognostic scores, such as the Model for End-Stage Liver Disease score. The definitive treatment for these patients is liver transplantation. Data related to the evolution and outcome of these patients when infected with SARS-CoV-2, including those undergoing transplantation, are scarce and contributions to the literature on this topic can help the adequate management of these patients, supporting the development of additional research and even guidelines. Thus, the publication of this report on two cirrhotic patients with COVID-19 who underwent liver transplantation is justified.
