Published online Aug 25, 2015. doi: 10.5495/wjcid.v5.i3.51
Peer-review started: February 9, 2015
First decision: March 6, 2015
Revised: March 17, 2015
Accepted: July 29, 2015
Article in press: August 3, 2015
Published online: August 25, 2015
Processing time: 199 Days and 0.4 Hours
Tick-borne diseases (TBDs) are a major public health concern that has increased in the past three decades. Nevertheless, emerging or reemerging TBDs may be still misdiagnosed. Molecular biology techniques for the screening of ticks, use of “Omics” approaches and the incorporation of analytical methods such as mass spectrometry or nuclear magnetic resonance, to the study of ticks and their associated pathogens or potential pathogens are promising tools for a more accurate differential diagnosis of TBDs. However, this huge amount of data needs to be carefully interpreted before being incorporated to the routine of clinical practice. In the meantime, a clinical approach and high level of suspicion keep being essential for the diagnosis and proper handling of TBDs.
Core tip: Tick-borne diseases (TBDs) are a major public health concern that has increased in the past three decades. Molecular biology techniques for the screening of ticks, use of “Omics” approaches and the incorporation of analytical methods to the study of ticks and their associated microorganisms are promising tools for a more accurate differential diagnosis of TBDs. Nevertheless, a clinical approach and high level of suspicion remain essential for the diagnosis and proper handling of TBDs before the incorporation of these innovative technologies to the routine in clinical practice.