Clinical and Translational Research
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Exp Med. Sep 20, 2024; 14(3): 93869
Published online Sep 20, 2024. doi: 10.5493/wjem.v14.i3.93869
Interaction between tumor stage and age on survival outcomes of patients with anaplastic thyroid cancer
Ayrton I Bangolo, Auda Auda, John Bukasa-Kakamba, Nayan Bhakta, Shraboni Dey, Anupriya lilhori, Gowry Reddy, Budoor Alqinai, Aman Sidiqui, Imranjot Sekhon, Barbare Khatiashvili, Iqra Abbas, Sandra Kunnel, Amer Jarri, Emelyn Martinez, Deborah Daoud, Ishita Gupta, Harshini Gompa, Silvanna Pender, Dana Aljaberi, Hamed Aljanaahi, Sandra S Kunnel, Yingxia Xiao, Yoontae Jung, Sneha Nagpaul, Afshan Naz, Tejaswee Mallela, Phyo Maung Maung, Ibtihal Y Khalaf, Soobee Kim, Roua Alrestom, Aditya Gajera, Hiba Alkealy, Deepti Kansal, Sonam Dhall, Sanya Satheesha, Simcha Weissman, Pierre Fwelo
Ayrton I Bangolo, Shraboni Dey, Budoor Alqinai, Aman Sidiqui, Imranjot Sekhon, Amer Jarri, Silvanna Pender, Sneha Nagpaul, Sanya Satheesha, Department of Internal Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States
Auda Auda, Nayan Bhakta, Anupriya lilhori, Gowry Reddy, Barbare Khatiashvili, Iqra Abbas, Sandra Kunnel, Emelyn Martinez, Deborah Daoud, Ishita Gupta, Harshini Gompa, Dana Aljaberi, Hamed Aljanaahi, Sandra S Kunnel, Yingxia Xiao, Yoontae Jung, Afshan Naz, Tejaswee Mallela, Phyo Maung Maung, Ibtihal Y Khalaf, Soobee Kim, Roua Alrestom, Aditya Gajera, Hiba Alkealy, Deepti Kansal, Sonam Dhall, Simcha Weissman, Department of Medicine, Palisades Medical Center, North Bergen, NJ 07047, United States
John Bukasa-Kakamba, Department of Endocrine and Metabolic Disorders, University of Kinshasa, Kinshasa Kinshasa, Congo
Pierre Fwelo, Department of Epidemiology, Human Genetics, and Environmental Sciences, UTHealth School of Public Health, Houston, TX 77030, United States
Author contributions: Bangolo A and Fwelo P designed the research study; Bangolo A, Auda A, Bukasa-Kakamba J, Bhakta N, Dey S, Lilhori A, Reddy G, Alqinai B, Sidiqui A, Sekhon I, Khatiashvili B, Abbas I, Kunnel S, Jarri A, Martinez E, Daoud D, Gupta I, Gompa H, Pender S, Aljaberi D performed the research; Bangolo A, Aljanaahi H, Kunnel SS, Xiao Y, Jung Y, Nagpaul S, Naz A, Mallela T, Maung PM, Khalaf IY, Kim S, Alrestom R, Gajera A, Alkealy H, Kansal D, Dhall S, Satheesha S, Weissman S analyzed the data and wrote the manuscript; All authors have read and approved the final manuscript.
Conflict-of-interest statement: No potential conflict of interest was reported by the authors.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ayrton I Bangolo, MBBS, MD, Doctor, Department of Internal Medicine, Palisades Medical Center, 7600 River Road, North Bergen, NJ 07047, United States. ayrtonbangolo@yahoo.com
Received: March 7, 2024
Revised: June 13, 2024
Accepted: June 25, 2024
Published online: September 20, 2024
Processing time: 175 Days and 3.4 Hours
Core Tip

Core Tip: Anaplastic thyroid cancer (ATC) represents a rare and highly aggressive subtype of thyroid cancer. Due to its rarity, limited information exists regarding the survival outcomes of patients with ATC. This study aims to provide the most current and comprehensive analysis of survival outcomes among ATC patients, with a specific emphasis on the interaction between two independent prognostic factors. Our findings indicate higher mortality rates in cases of advanced-stage tumors with direct extension and distant metastasis. Nevertheless, patients who underwent aggressive therapy exhibited improved overall survival rates.