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©The Author(s) 2018.
World J Crit Care Med. Sep 7, 2018; 7(4): 46-51
Published online Sep 7, 2018. doi: 10.5492/wjccm.v7.i4.46
Published online Sep 7, 2018. doi: 10.5492/wjccm.v7.i4.46
Table 1 Comparison of nasal intermittent mandatory ventilation responders to nasal intermittent mandatory ventilation non-responders - baseline characteristics1
| Baseline characteristic | NIMV responders (n = 36) | NIMV non-responders (n = 6) | Total (n = 42) | P value |
| Age (mo) | 4 (0.5-20, IQR = 6.4) | 5.2 (0.5-28.1, IQR = 12.6) | 4 (0.5-28.1, IQR = 7) | 0.69 |
| Admission weight (kg) | 4.9 (2.3-12, IQR = 4.3) | 7.1 (2.6-10.9, IQR = 4.8) | 5.1 (2.3-12, IQR = 4.4) | 0.39 |
| T Max in Celsius (range) | 38 (36.6-40, IQR = 1.6) | 38.9 (37.4-39.7, IQR = 1.7) | 38.1 (36.6-40, IQR = 1.6) | 0.2 |
| Respiratory rate (in breaths per minute) | 60 (24-97, IQR = 19) | 56 (42-77, IQR = 32) | 60 (24-97, IQR = 22) | 0.76 |
| O2 saturation (%) | 98 (68-100, IQR = 5.5) | 99 (98-100, IQR = 2) | 98.5 (68-100, IQR = 5) | 0.31 |
| Heart rate (beats per minute) | 152.5 (95-205, IQR = 34.5) | 158.5 (127-210, IQR = 24) | 153.5 (95-210, IQR = 33) | 0.99 |
| Systolic blood pressure (mmHg) | 100 (71-129, IQR = 21) | 112 (81-120, IQR = 25) | 103 (71-129, IQR = 20) | 0.3 |
| Diastolic blood pressure (mmHg) | 51 (37-84, IQR = 20) | 59.5 (43-81, IQR = 25) | 51 (37-84, IQR = 22) | 0.41 |
| PRISM-III score | 0 (0-11, IQR = 0) | 1 (0-7, IQR = 3) | 0 (0-11, IQR = 0) | 0.08 |
Table 2 Diagnoses causing acute respiratory failure in nasal intermittent mandatory ventilation responders vs nasal intermittent mandatory ventilation non-responders1
| Diagnosis | NIMV responders n (%) | NIMV non-responders n (%) | Total (%) | P value |
| Asthma exacerbation | 1 (3) | 2 (33) | 3 (7) | 0.11 |
| Bronchiolitis | 28 (78) | 3 (50) | 31 (74) | |
| Heart failure | 1 (3) | 0 (0) | 1 (2) | |
| Pneumonia | 3 (8) | 1 (17) | 4 (10) | |
| Viral syndrome | 3 (8) | 0 (0) | 3 (7) |
Table 3 Comparison of nasal intermittent mandatory ventilation responders to nasal intermittent mandatory ventilation non-responders - maximum support and clinical outcomes1
| Support or outcome variable | NIMV responders (n = 36) | NIMV non-responders (n = 6) | Total (n = 42) | P value |
| Max delta P of NIMV (cmH2O) | 16 (6-26, IQR = 6.5) | 17.5 (10-30, IQR = 6) | 16.5 (6-30, IQR = 6) | 0.68 |
| Max FIO2 of NIMV (%) | 40 (25-100, IQR = 22.5) | 42.5 (30-70, IQR = 10) | 40 (25-100, IQR = 15) | 0.84 |
| Max PEEP of NIMV (cmH2O) | 6 (5-8, IQR = 2) | 5 (5-8, IQR = 2) | 6 (5-8, IQR = 2) | 0.37 |
| Max rate of NIMV (breaths per minute) | 30 (20-70, IQR = 3.5) | 30 (20-60, IQR = 5) | 30 (20-70, IQR = 2) | 0.32 |
| Time to max FIO2 (h) | 0 (0-119, IQR = 1.5) | 0 (0-29.5, IQR = 6) | 0 (0-119, IQR = 2) | 0.75 |
| Time to max setting (h) | 1 (0-48, IQR = 9) | 3 (0-29.5, IQR = 20) | 1 (0-48, IQR = 10) | 0.8 |
| Hospital length of stay (d) | 7 (3-30, IQR = 3.5) | 9 (4-14, IQR = 7) | 7.5 (3-30, IQR = 4) | 0.73 |
| PICU length of stay (d) | 6 (3-30, IQR = 3) | 6.5 (3-14, IQR = 5) | 6 (3-30, IQR = 3) | 0.64 |
| Total duration of NIMV (h) | 65 (5-240, IQR = 47.5) | 6.5 (0.5-30, IQR = 24) | 59.5 (0.5-240, IQR = 53) | 0.001 |
| Total duration of all respiratory support (h) | 94.5 (28-254, IQR = 60) | 115 (65-230, IQR = 31.5) | 95.8 (28-254, IQR = 57) | 0.3 |
- Citation: Wang BC, Pei T, Lin CB, Guo R, Elashoff D, Lin JA, Pineda C. Clinical characteristics and outcomes associated with nasal intermittent mandatory ventilation in acute pediatric respiratory failure. World J Crit Care Med 2018; 7(4): 46-51
- URL: https://www.wjgnet.com/2220-3141/full/v7/i4/46.htm
- DOI: https://dx.doi.org/10.5492/wjccm.v7.i4.46