Interest of D-dimer level, severity of COVID-19 and cost of management in Gabon

Table 1 Demographic and clinical data according to D-dimer level, n (%)

	Total (n = 3004)	Normal D-dimer level (n = 1027)	Abnormal D-dimer level (n = 1977)	P value
Gender				< 0.001
Female	1605 (53.43)	504 (49.1)	1101 (55.7)
Age (year)				< 0.001
Mean (SD)	50.17 (16.92)	47.19 (15.53)	51.72 (17.40)
Median (interquartile range)	48.00 (24.00)	45.00 (21.00)	51.00 (26.00)
Quartile 1, quartile 3	38.00, 62.00	37.00, 58.00	38.00, 64.00
Minimum, maximum	2.00, 101.00	2.00, 99.00	2.00, 101.00
Year				< 0.001
2020	612 (20.37)	222 (21.62)	390 (19.73)
2021	523 (17.41)	143 (13.92)	380 (19.22)
2022	482 (16.05)	147 (14.31)	335 (16.94)
2023	1387 (46.17)	515 (50.15)	872 (44.11)
Severity of coronavirus disease 2019				< 0.001
Severe	1425 (47.44)	294 (28.63)	1131 (57.21)

Table 2 Logistics regression of factors associated with severity of coronavirus disease 2019

	Univariable OR (95%CI)	P value	Multivariable OR (95%CI)	P value
Gender
Female vs male	0.74 (0.64-0.85)	< 0.001	0.70 (0.60-0.82)	< 0.001
Age (year)	1.01 (1.01-1.02)	< 0.001	1.01 (1.01-1.01)	< 0.001
Year
2021 vs 2020	0.25 (0.19-0.32)	< 0.001	0.18 (0.14-0.24)	< 0.001
2022 vs 2020	0.29 (0.22-0.37)	< 0.001	0.24 (0.18-0.31)	< 0.001
2023 vs 2020	0.22 (0.18-0.27)	< 0.001	0.19 (0.15-0.24)	< 0.001
Abnormal D-dimer level
D-dimer level vs normal D-dimer level	3.33 (2.84-3.92)	< 0.001	3.89 (3.27-4.66)	< 0.001

OR: Odds ratios.