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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Crit Care Med. Mar 9, 2025; 14(1): 100486
Published online Mar 9, 2025. doi: 10.5492/wjccm.v14.i1.100486
Published online Mar 9, 2025. doi: 10.5492/wjccm.v14.i1.100486
Interest of D-dimer level, severity of COVID-19 and cost of management in Gabon
Berthe A Iroungou, Annicet-Clotaire Dikoumba, Unité Mixte de Recherche, Centre International de Recherches Médicales de Franceville et le Service de Santé Militaire, Libreville 20404, Estuaire, Gabon
Arnaud Nze O, AP-HP Health Economics, Research Unit, Htel Dieu Hospital, Paris 75004, Ile-de-France, France
Helga M Kandet Y, Laboratory, Hôpital D'Instruction des Armées D'Akanda, Libreville 20404, Estuaire, Gabon
Neil-Michel Longo-Pendy, Unité de Recherche en Écologie de la Santé, Centre Interdisciplinaire de Recherches Médicales de Franceville, Franceville 769, Gabon
Nina D Mezogho-Obame, Laboratory, Hôpital D'Instruction des Armées Omar Bongo Ondimba, Libreville 20404, Estuaire, Gabon
Guignali L Mangouka, Department of Medecine Polyvalente, Hôpital D'Instruction des Armées Omar Bongo Ondimba, Libreville 20404, Estuaire, Gabon
Co-corresponding authors: Berthe A Iroungou and Guignali L Mangouka.
Author contributions: Iroungou BA served as the guarantor of the study and was responsible for its design; Iroungou BA, Nze OA, and Mangouka GL played key roles in data analysis, interpretation, and drafting the initial manuscript; Kandet YHM and Mezogho-Obame ND were involved in data acquisition; Longo-Pendy NM contributed to data analysis; Dikoumba AC provided additional support in data analysis; Mangouka GL critically revised the manuscript for important intellectual content; all of the authors read and approved the final version of the manuscript to be published.
Institutional review board statement: The study was reviewed and approved by National Ethical Committee CNER.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: Additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Berthe A Iroungou, DSc, MHSc, PhD, Assistant Professor, Research Scientist, Unité Mixte de Recherche, Centre International de Recherches Médicales de Franceville et le Service de Santé Militaire, Pk9, Libreville 20404, Estuaire, Gabon.
Received: August 18, 2024
Revised: October 2, 2024
Accepted: October 30, 2024
Published online: March 9, 2025
Processing time: 115 Days and 13.5 Hours
Revised: October 2, 2024
Accepted: October 30, 2024
Published online: March 9, 2025
Processing time: 115 Days and 13.5 Hours
Core Tip
Core Tip: D-dimer, a key biomarker produced during blood clot breakdown, is widely used to diagnose thrombotic conditions such as deep vein thrombosis and pulmonary embolism. Elevated D-dimer levels have been consistently linked to increased coronavirus disease 2019 (COVID-19) severity and mortality risk. This study highlights the role of D-dimer in predicting COVID-19 outcomes in Gabon. Understanding its role can help optimize healthcare resource allocation, improve patient outcomes, and mitigate the economic burden associated with severe COVID-19 cases in resource-limited settings.