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World J Crit Care Med. Nov 4, 2013; 2(4): 40-47
Published online Nov 4, 2013. doi: 10.5492/wjccm.v2.i4.40
Published online Nov 4, 2013. doi: 10.5492/wjccm.v2.i4.40
Neurologic complications and neurodevelopmental outcome with extracorporeal life support
Amit Mehta, Laura M Ibsen, Division of Pediatric Critical Care Medicine, Department of Pediatrics, Oregon Health and Sciences University, Portland, OR 97239, United States
Author contributions: Mehta A, Ibsen LM wrote the paper.
Correspondence to: Amit Mehta, MD, Division of Pediatric Critical Care Medicine, Department of Pediatrics, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, United States. mehtaa@ohsu.edu
Telephone: +1-503-4949000 Fax: +1-503-4944951
Received: July 10, 2013
Revised: July 27, 2013
Accepted: August 4, 2013
Published online: November 4, 2013
Processing time: 113 Days and 8.7 Hours
Revised: July 27, 2013
Accepted: August 4, 2013
Published online: November 4, 2013
Processing time: 113 Days and 8.7 Hours
Core Tip
Core tip: Extracorporeal life support is used to support patients of all ages with refractory cardiac and/or respiratory failure. It is associated with acute central nervous system complications and with long- term neurologic morbidity. Many patients treated with extracorporeal membrane oxygenation (ECMO) have acute neurologic complications, including seizures, hemorrhage, infarction, and brain death. In this review paper, we review the incidence of and factors associated with neurologic complications associated with the use of ECMO and the associated long term neurologic outcomes of patients treated with ECMO.