Srivastava S, Garg I. Thrombotic complications post liver transplantation: Etiology and management. World J Crit Care Med 2024; 13(4): 96074 [DOI: 10.5492/wjccm.v13.i4.96074]
Corresponding Author of This Article
Swati Srivastava, PhD, Senior Scientist, Defence Institute of Physiology and Allied Sciences, Defence Research and Development organization, Lucknow Road, Timarpur, Delhi 110054, India. sri_swati@rediffmail.com
Research Domain of This Article
Transplantation
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Crit Care Med. Dec 9, 2024; 13(4): 96074 Published online Dec 9, 2024. doi: 10.5492/wjccm.v13.i4.96074
Thrombotic complications post liver transplantation: Etiology and management
Swati Srivastava, Iti Garg
Swati Srivastava, Iti Garg, Defence Institute of Physiology and Allied Sciences, Defence Research and Development organization, Delhi 110054, India
Author contributions: Srivastava S was responsible for conceptualization and writing of manuscript; Garg I was responsible for editing and formatting of manuscript; all of the authors read and approved the final version of the manuscript to be published.
Conflict-of-interest statement: The authors of the manuscript declare no conflict of Interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Swati Srivastava, PhD, Senior Scientist, Defence Institute of Physiology and Allied Sciences, Defence Research and Development organization, Lucknow Road, Timarpur, Delhi 110054, India. sri_swati@rediffmail.com
Received: April 26, 2024 Revised: October 1, 2024 Accepted: October 24, 2024 Published online: December 9, 2024 Processing time: 188 Days and 2.9 Hours
Core Tip
Core Tip: Liver transplantation (LT) is the most widely accepted standard for treatment of end stage liver disease. Despite surgical advancements and improvements in post-operative therapeutic regime, there exists high morbidity and mortality rate due to biliary complications, renal or abdominal malfunction, pulmonary dysfunction as well as thrombotic events. Though vascular complications are seldom post orthotopic LT (OLT), they result in high incidences of morbidity and mortality. Vascular dysfunction post OLT leading to thrombotic event could be either arterial or venous. Its clinical feature depends on its type, presentation (early or late) and time taken for diagnosis. Thrombotic complications are one of the leading causes of the failure of LT. There is very scanty data available on the possible risk factors amongst individuals who develop thrombotic complications post LT. It is extremely important to monitor vascular graft supply and to ensure effective screening of every patient undergoing LT.
