Systematic Reviews
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Crit Care Med. Sep 9, 2024; 13(3): 97205
Published online Sep 9, 2024. doi: 10.5492/wjccm.v13.i3.97205
Optic nerve sheath diameters in nontraumatic brain injury: A scoping review and role in the intensive care unit
Madhura Bhide, Deven Juneja, Omender Singh, Shakya Mohanty
Madhura Bhide, Shakya Mohanty, Institute of Critical Care Medicine, Kalinga Institute of Medical Sciences, Bhubaneshwar 751024, Odisha, India
Deven Juneja, Omender Singh, Institute of Critical Care Medicine, Max Super Speciality Hospital, Saket, New Delhi 110017, India
Author contributions: Bhide M, Juneja D and Singh O researched the subject, performed data acquisition; Bhide M and Mohanty S performed the majority of the writing; Singh O and Juneja D provided inputs in writing the paper and reviewed the final draft.
Conflict-of-interest statement: The authors affirm that they have no conflicts of interest pertaining to the subject matter discussed in this paper.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Deven Juneja, DNB, MBBS, Director, Institute of Critical Care Medicine, Max Super Speciality Hospital, 1 Press Enclave Road, Saket, New Delhi 110017, India. devenjuneja@gmail.com
Received: May 25, 2024
Revised: July 16, 2024
Accepted: August 6, 2024
Published online: September 9, 2024
Processing time: 96 Days and 10.6 Hours
Core Tip

Core Tip: Neuromonitoring in critically ill patients is challenging as many patients are unfit for invasive intracranial pressure (ICP) monitoring or unstable to transport for imaging. Bedside ultrasonography based optic nerve sheath diameter (ONSD) has been proven to be a reliable option in patients with traumatic brain injury (TBI). However, it’s efficacy has not been extensively evaluated in neuro-medical patients. In this review, we analyzed data from 37 articles which had compared ONSD with other established modalities of measuring ICP in non-TBI patients. The analyzed data suggests that ONSD may be a useful tool to detect raised ICP and predict outcome in patients with acute ischemic stroke, intracerebral bleed and intracranial infection. However, further large-scale randomized trials are required, especially in patients with septic metabolic encephalopathy, dysnatremias and aneurysmal subarachnoid hemorrhage, before it is routinely employed in managing neuro-medical patients with elevated ICP.