Systematic Reviews
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Crit Care Med. Jun 9, 2024; 13(2): 92585
Published online Jun 9, 2024. doi: 10.5492/wjccm.v13.i2.92585
Effects of combined aerobic, resistance and inspiratory training in patients with pulmonary hypertension: A systematic review
Christos Kourek, Antonia Zachariou, Eleftherios Karatzanos, Michalis Antonopoulos, Theodora Soulele, Andreas Karabinis, Serafim Nanas, Stavros Dimopoulos
Christos Kourek, Antonia Zachariou, Eleftherios Karatzanos, Michalis Antonopoulos, Stavros Dimopoulos, Department of Clinical Ergospirometry, Exercise and Rehabilitation Laboratory, 1st Department of Critical Care Medicine, Evangelismos Hospital, National and Kapodistrian University of Athens, Athens 10676, Greece
Christos Kourek, Department of Cardiology, 417 Army Share Fund Hospital of Athens, Athens 11521, Greece
Michalis Antonopoulos, Cardiac Surgery ICU, Onassis Cardiac Surgery center, Athens 17674, Attica, Greece
Theodora Soulele, Stavros Dimopoulos, Cardiac Surgery ICU, Onassis Cardiac Surgery Center, Athens 17674, Greece
Andreas Karabinis, Cardiac Surgery Intensive Care Unit, Onassis Cardiac Surgery Center, Athens 17674, Greece
Serafim Nanas, Department of Clinical Ergospirometry, Exercise and Rehabilitation Laboratory, National and Kapodistrian University of Athens, Athens 10676, Greece
Author contributions: Dimopoulos S designed the research; Kourek C and Zachariou A performed the research; Kourek C, Zachariou A, Karatzanos E, Antonopoulos M, Soulele T, Karabinis A, Nanas S and Dimopoulos S analyzed the data; Kourek C and Dimopoulos S wrote the paper; All authors revised the paper.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Stavros Dimopoulos, PhD, Director, Department of Clinical Ergospirometry, Exercise and Rehabilitation Laboratory, 1st Department of Critical Care Medicine, Evangelismos Hospital, National and Kapodistrian University of Athens, 45-47 Ipsilantou Street, Athens 10676, Greece. stdimop@gmail.com
Received: January 30, 2024
Revised: April 29, 2024
Accepted: May 21, 2024
Published online: June 9, 2024
Processing time: 125 Days and 0.3 Hours
Core Tip

Core Tip: Pulmonary hypertension (PH) is characterized by endothelial dysfunction and impaired vasoreactivity. Data regarding the effects of combined exercise training programs in patients with PH still remains limited. The effects of combined exercise training programs on exercise capacity and quality of life in patients with PH. We observed that combined exercise training has beneficial effects on functional capacity, assessed by peak VO2 or 6-min walking test, and quality of life in PH. However, further research is required in order to create the maximum beneficial individualized exercise training protocols.