Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Crit Care Med. Jun 9, 2024; 13(2): 92458
Published online Jun 9, 2024. doi: 10.5492/wjccm.v13.i2.92458
Extracorporeal organ support for critically ill patients: Overcoming the past, achieving the maximum at present, and redefining the future
Panagiotis Papamichalis, Katerina G Oikonomou, Maria Xanthoudaki, Asimina Valsamaki, Apostolia-Lemonia Skoura, Sophia K Papathanasiou, Achilleas Chovas
Panagiotis Papamichalis, Katerina G Oikonomou, Maria Xanthoudaki, Asimina Valsamaki, Achilleas Chovas, Intensive Care Unit, General Hospital of Larissa, Larissa 41221, Greece
Apostolia-Lemonia Skoura, Department of Transfusion Medicine, University Hospital of Larissa, Larissa 41110, Greece
Sophia K Papathanasiou, Department of Internal Medicine, General Hospital of Larissa, Larissa 41221, Greece
Author contributions: Papamichalis P, Oikonomou KG and Xanthoudaki M designed the review; Skoura AL and Papathanasiou SK assisted in data gathering; Papamichalis P, Oikonomou KG, Xanthoudaki M, Valsamaki A and Papathanasiou SK wrote the final version of the manuscript; Oikonomou KG performed English editing; Chovas A critically reviewed the paper.
Conflict-of-interest statement: The authors declare having no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Panagiotis Papamichalis, MD, PhD, Consultant Physician-Scientist, Intensive Care Unit, General Hospital of Larissa, 1 Tsakalof, Larissa 41221, Greece.ppapamih@med.uth.gr
Received: January 26, 2024
Revised: February 17, 2024
Accepted: March 26, 2024
Published online: June 9, 2024
Processing time: 128 Days and 23.2 Hours
Core Tip

Core Tip: Supportive therapy remains the cornerstone of care for critically ill patients. Nowadays, extracorporeal organ support (ECOS) systems have made remarkable technological progress and have become widely available in almost every intensive care unit around the world. Long-lasting multiple organ support therapy is feasible for the kidneys, liver, heart, and lungs, while the use of ECOS systems for suppression of various hyperinflammatory conditions, such as sepsis and coronavirus disease 2019, during cardiac surgery, and after cardiac arrest, is an emerging and rapidly recognized indication. Nowadays, combinations of supportive strategies have been developed tailored to the needs of each patient, leading to new ways of understanding and managing multiple organ failure. Moreover, the crosstalk between native and artificial organs is a novel concept that must be further studied, while further research is needed to clarify the indications, therapeutic protocols, and groups of patients suitable for such therapies.