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World J Crit Care Med. Jun 9, 2024; 13(2): 91435
Published online Jun 9, 2024. doi: 10.5492/wjccm.v13.i2.91435
Diagnosis and management of severe pulmonary and extrapulmonary tuberculosis in critically ill patients: A mini review for clinicians
Dominic Ti Ming Tan, Kay Choong See
Dominic Ti Ming Tan, Kay Choong See, Department of Medicine, National University Hospital, Singapore 119228, Singapore
Author contributions: Tan DTM performed the literature review and wrote the paper; See KC oversaw the write up and contributed to the final edit.
Conflict-of-interest statement: The authors declare that there are no conflict-of-interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dominic Ti Ming Tan, MBChB, Doctor, Department of Medicine, National University Hospital, 1E Kent Ridge Road, Singapore 119228, Singapore. dominic.tan.ti.ming@gmail.com
Received: December 30, 2023
Revised: February 4, 2024
Accepted: March 25, 2024
Published online: June 9, 2024
Processing time: 155 Days and 15.9 Hours
Core Tip

Core Tip: Tuberculosis requiring high dependency or intensive care support is rare yet carries a high morbidity and mortality rate. Whilst pulmonary disease remains the most common manifestation, the management of other lesser known extrapulmonary disease also pose their own set of challenges. Modern advances in diagnosis and treatment options aim to tackle the challenges of delayed recognition and reduce complication rates. We discuss the myriad of ways tuberculosis can manifest in the intensive care unit, the challenges in its management, and the diagnostic tools available for early diagnosis and treatment.