Minireviews
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Crit Care Med. Jul 9, 2022; 11(4): 219-227
Published online Jul 9, 2022. doi: 10.5492/wjccm.v11.i4.219
Challenges in hyperglycemia management in critically ill patients with COVID-19
Rajesh Kethireddy, Darshan Gandhi, Asim Kichloo, Love Patel
Rajesh Kethireddy, Love Patel, Division of Hospital Medicine, Abbott Northwestern Hospital, Allina Health, Minneapolis, MN 55407, United States
Darshan Gandhi, Department of Diagnostic Radiology, University of Tennessee Health Science Center, Memphis, TN 38103, United States
Asim Kichloo, Internal Medicine, Central Michigan University School of Medicine, Mt Pleasant, MI 48859, United States
Author contributions: Kethireddy R conceived the idea of this article and contributed to the writing and revision of the manuscript substantially; Gandhi D contributed to the discussion and revision of the manuscript substantially; Kichloo A contributed to the manuscript format and editing of the manuscript substantially; Patel L contributed to the manuscript formation and reference numbering of the manuscript.
Conflict-of-interest statement: The authors declare that they have no competing or conflicts of interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Darshan Gandhi, MD Assistant Professor, Department of Diagnostic Radiology, University of Tennessee Health Science Center, 920 Madison Ave, Memphis, TN 38103, United States. darshangandhi7@gmail.com
Received: April 2, 2021
Peer-review started: April 2, 2021
First decision: July 31, 2021
Revised: August 10, 2021
Accepted: May 8, 2022
Article in press: May 8, 2022
Published online: July 9, 2022
Processing time: 460 Days and 12.4 Hours
Core Tip

Core Tip: Data from the corona virus disease 2019 (COVID-19) pandemic indicates that individuals with diabetes are more likely to experience hyperglycemia related complications including diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome. These patients often require hospitalization to intensive care units. In this article we intend to describe the pathophysiology of hyperglycemia in critically ill patients with COVID-19 infection, challenges encountered in managing hyperglycemia, and review some potential solutions to address them.