Copyright
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Crit Care Med. Jan 9, 2022; 11(1): 33-39
Published online Jan 9, 2022. doi: 10.5492/wjccm.v11.i1.33
Published online Jan 9, 2022. doi: 10.5492/wjccm.v11.i1.33
Endotracheal intubation sedation in the intensive care unit
Pritee Tarwade, Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN 55905, United States
Nathan J Smischney, Anesthesiology and Perioperative Medicine, Division of Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, United States
Author contributions: Tarwade P performed most of the writing, prepared the figures and tables; Smischney NJ provided input in writing the paper and coordinated the writing of the paper.
Conflict-of-interest statement: Nathan Smischney has a patent application titled Ketamine and Propofol Admixture: #16/606,056, pending.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Nathan J Smischney, MD, MSc, Associate Professor, Anesthesiology and Perioperative Medicine, Division of Critical Care Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, United States. smischney.nathan@mayo.edu
Received: April 29, 2021
Peer-review started: April 29, 2021
First decision: June 17, 2021
Revised: June 21, 2021
Accepted: November 4, 2021
Article in press: November 4, 2021
Published online: January 9, 2022
Processing time: 251 Days and 2.1 Hours
Peer-review started: April 29, 2021
First decision: June 17, 2021
Revised: June 21, 2021
Accepted: November 4, 2021
Article in press: November 4, 2021
Published online: January 9, 2022
Processing time: 251 Days and 2.1 Hours
Core Tip
Core Tip: Intensive care unit endotracheal intubations are associated with a higher risk of complications such as hypotension, hypoxemia, and cardiac arrest when compared to non-intensive care unit endotracheal intubations. A necessity of endotracheal intubations, sedation, is a modifiable risk factor in the pathway to cardiovascular instability. The goal of this review is to present the pros and cons of each sedative agent used for endotracheal intubation while comparing the outcomes. This will help the reader to make an informed decision when choosing a sedative agent for endotracheal intubation in the intensive care unit.