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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Crit Care Med. Sep 9, 2021; 10(5): 183-193
Published online Sep 9, 2021. doi: 10.5492/wjccm.v10.i5.183
Published online Sep 9, 2021. doi: 10.5492/wjccm.v10.i5.183
Role of proning and positive end-expiratory pressure in COVID-19
Kejal D Gandhi, Department of Medicine, Georgetown University/Medstar Washington Hospital Center, Washigton, DC 20010, United States
Munish Sharma, Pahnwat Tonya Taweesedt, Department of Medicine, Corpus Christi Medical Center, Corpus Christi, TX 78412, United States
Salim Surani, Department of Medicine, Texas A&M University, Corpus Christi, TX 78404, United States
Author contributions: Gandhi KD was involved in literature search and writing of the manuscript; Sharma M and Taweesedt PT was involved in writing and review of the manuscript; Surani S was involved in the idea, writing, and review of the manuscript.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Salim Surani, MD, Adjunct Professor, Department of Medicine, Texas A&M University, 701 Ayers Street, Corpus Christi, TX 78404, United States.
Received: February 21, 2021
Peer-review started: February 21, 2021
First decision: May 6, 2021
Revised: May 16, 2021
Accepted: July 29, 2021
Article in press: July 29, 2021
Published online: September 9, 2021
Processing time: 199 Days and 11.2 Hours
Peer-review started: February 21, 2021
First decision: May 6, 2021
Revised: May 16, 2021
Accepted: July 29, 2021
Article in press: July 29, 2021
Published online: September 9, 2021
Processing time: 199 Days and 11.2 Hours
Core Tip
Core Tip: Optimizing and titrating the positive end-expiratory pressure (PEEP) in acute respiratory distress syndrome (ARDS) patients has been studied widely in the critical care world. However, the ARDS caused by coronavirus disease 2019 (COVID-19) possesses a challenge due to relatively preserved compliance in the early phase of this disease and questions the guidelines which have been long established. Proning, though tedious and cumbersome, which has been traditionally proved to improve oxygenation and survival benefits in ARDS patients has been extensively applied in COVID-19 patients. This article critically analyzes the role of PEEP and proning in COVID-19 patients.