See KC. Acute cor pulmonale in patients with acute respiratory distress syndrome: A comprehensive review. World J Crit Care Med 2021; 10(2): 35-42 [PMID: 33728264 DOI: 10.5492/wjccm.v10.i2.35]
Corresponding Author of This Article
Kay Choong See, FCCP, FRCP, MBBS, MRCP, Doctor, Department of Medicine, National University Hospital, 1E Kent Ridge Rd, NUHS Tower Block Level 10, Singapore 119228, Singapore. kay_choong_see@nuhs.edu.sg
Research Domain of This Article
Medicine, General & Internal
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Crit Care Med. Mar 9, 2021; 10(2): 35-42 Published online Mar 9, 2021. doi: 10.5492/wjccm.v10.i2.35
Acute cor pulmonale in patients with acute respiratory distress syndrome: A comprehensive review
Kay Choong See
Kay Choong See, Department of Medicine, National University Hospital, Singapore 119228, Singapore
Author contributions: See KC collected the data and wrote the paper; See KC read and approved the final manuscript.
Conflict-of-interest statement: See KC declares no relevant conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kay Choong See, FCCP, FRCP, MBBS, MRCP, Doctor, Department of Medicine, National University Hospital, 1E Kent Ridge Rd, NUHS Tower Block Level 10, Singapore 119228, Singapore. kay_choong_see@nuhs.edu.sg
Received: December 6, 2020 Peer-review started: December 6, 2020 First decision: December 31, 2020 Revised: January 1, 2020 Accepted: January 28, 2021 Article in press: January 28, 2021 Published online: March 9, 2021 Processing time: 84 Days and 17 Hours
Core Tip
Core Tip: Acute respiratory distress syndrome (ARDS)-related acute cor pulmonale (ACP) is associated with adverse hemodynamic and survival outcomes. It is an echocardiographic diagnosis marked by combined right ventricular dilatation and septal dyskinesia. Checking for ARDS-related ACP should be done in patients with ≥ 2 of 4 risk factors: Pneumonia, arterial partial pressure of oxygen-to-inspired oxygen fraction ratio < 150 mmHg, arterial partial pressure of carbon dioxide ≥ 48 mmHg, and driving pressure ≥ 18 cmH2O. Treatments include ventilator adjustment (aiming for arterial partial pressure of carbon dioxide < 60 mmHg, plateau pressure < 27 cmH2O, driving pressure < 17 cmH2O), prone positioning, fluid balance optimization and pharmacotherapy.
