Meier A, Kock KS. Need for oxygen therapy and ventilatory support in premature infants in a hospital in Southern Brazil. World J Crit Care Med 2022; 11(3): 160-168 [PMID: 36331991 DOI: 10.5492/wjccm.v11.i3.160]
Corresponding Author of This Article
Kelser de Souza Kock, PhD, Physiotherapist, Professor, Department of Physiotherapy, University of South of Santa Catarina, José Acácio Moreira Street-787, Tubarão 88704-001, SC, Brazil. kelserkock@yahoo.com.br
Research Domain of This Article
Critical Care Medicine
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Crit Care Med. May 9, 2022; 11(3): 160-168 Published online May 9, 2022. doi: 10.5492/wjccm.v11.i3.160
Need for oxygen therapy and ventilatory support in premature infants in a hospital in Southern Brazil
Amanda Meier, Kelser de Souza Kock
Amanda Meier, Kelser de Souza Kock, Department of Physiotherapy, University of South of Santa Catarina, Tubarão 88704-001, SC, Brazil
Author contributions: Meier A performed the data collection and wrote the manuscript; Kock KS performed the statistical analysis and revision and editing of the manuscript.
Institutional review board statement: This research project was approved by the Ethics Committee in Human Beings of (University of Southern Santa Catarina, Brazil) UNISUL under the number of the opinion 3.529.438, CAAE: 17573519.2.0000.5369.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The informed consent form was waived because only information from the electronic records was collected and the patients were not hospitalized during the study period.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kelser de Souza Kock, PhD, Physiotherapist, Professor, Department of Physiotherapy, University of South of Santa Catarina, José Acácio Moreira Street-787, Tubarão 88704-001, SC, Brazil. kelserkock@yahoo.com.br
Received: March 5, 2021 Peer-review started: March 5, 2021 First decision: March 31, 2021 Revised: May 19, 2021 Accepted: April 3, 2022 Article in press: April 3, 2022 Published online: May 9, 2022 Processing time: 427 Days and 14.6 Hours
ARTICLE HIGHLIGHTS
Research background
Prematurity may be associated with some degree of respiratory failure.
Research motivation
Clinical recognition of premature infants at risk is important for appropriate management of ventilatory support.
Research objectives
To assess maternal and newborn factors related to the need for ventilatory support.
Research methods
A retrospective cohort conducted in a private hospital in southern Brazil consisted of preterm infants with gestational age < 37 wk.
Research results
We evaluated 90 premature infants with median (p25-p75) gestational age of 34.0 (31.9-35.4) wk. The utilization rate of oxygen therapy, continuous positive airway pressure and mechanical ventilation was 12 (13.3%), 37 (41.1%) and 13 (14.4%), respectively. The median (p25-p75) length of stay was 12.0 (5.0-22.2) d, with 10 (11.1%) deaths. A statistical association was observed with the use of mechanical ventilation and gestational age < 28 wk, lower maternal age, low birth weight, Apgar < 8 and neonatal deaths.
Research conclusions
The need for mechanical ventilation in premature infants was related to low birth weight, extreme prematurity and low Apgar.
Research perspectives
Other clinical indicators for predicting ventilatory support in premature infants can be used, such as monitoring vital signs and their variability measures.
