Rodríguez-Torres J, Cabrera-Martos I, López-López L, Quero-Valenzuela F, Cahalin LP, Valenza MC. Reduced exercise capacity and self-perceived health status in high-risk patients undergoing lung resection. World J Crit Care Med 2021; 10(5): 232-243 [PMID: 34616659 DOI: 10.5492/wjccm.v10.i5.232]
Corresponding Author of This Article
Marie Carmen Valenza, PhD, Full Professor, Fisioterapia, University of Granada, Avda. de la Ilustración, 60, Granada 18016, Spain. cvalenza@ugr.es
Research Domain of This Article
Critical Care Medicine
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Crit Care Med. Sep 9, 2021; 10(5): 232-243 Published online Sep 9, 2021. doi: 10.5492/wjccm.v10.i5.232
Reduced exercise capacity and self-perceived health status in high-risk patients undergoing lung resection
Janet Rodríguez-Torres, Irene Cabrera-Martos, Laura López-López, Florencio Quero-Valenzuela, Lawrence Patrick Cahalin, Marie Carmen Valenza
Janet Rodríguez-Torres, Irene Cabrera-Martos, Laura López-López, Florencio Quero-Valenzuela, Marie Carmen Valenza, Fisioterapia, University of Granada, Granada 18016, Spain
Florencio Quero-Valenzuela, Cardiothoracic Surgery Department, Virgen de las Nieves Hospital, Granada 18016, Spain
Lawrence Patrick Cahalin, Physical Therapy, University of Miami, Miami, FL 33124, United States
Author contributions: Valenza MC was the guarantor and designed the study; Cabrera-Martos I, Rodríguez-Torres J and López-López L participated in the acquisition, analysis and interpretation of the data and drafted the initial manuscript; Quero-Valenzuela F and Cahalin LP revised the article critically for important intellectual content.
Institutional review board statement: The study protocol was reviewed and approved by the University of Granada Ethics Committee.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: None of the authors presented conflict of interest.
Data sharing statement: The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to their containing information could compromise the privacy of research participants.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Marie Carmen Valenza, PhD, Full Professor, Fisioterapia, University of Granada, Avda. de la Ilustración, 60, Granada 18016, Spain. cvalenza@ugr.es
Received: December 17, 2020 Peer-review started: December 17, 2020 First decision: May 6, 2021 Revised: May 10, 2021 Accepted: July 6, 2021 Article in press: July 6, 2021 Published online: September 9, 2021 Processing time: 265 Days and 21.2 Hours
ARTICLE HIGHLIGHTS
Research background
Lung cancer resection still produces a high incidence of postoperative pulmonary complications. High-risk lung cancer patients are more likely to have postoperative pulmonary complications. Exercise capacity and functionality is affected in lung cancer patients after hospitalization.
Research motivation
High-risk patients present more complications after hospitalization. Upper and lower limb exercise capacity could be affected in these patients.
Research objectives
To determine if there are differences between high and low-risk patients in exercise capacity. To identify differences in self-perceived health status depending on the risk of developing postoperative pulmonary complications at discharge and 1 mo after hospitalization.
Research methods
This was an observational prospective cohort study conducted between April 2017 and July 2018. Inclusion criteria included: to be between 18-years-old and 80-years-old and to be informed about the study purpose. Patients were divided into two groups according to the risk profile criteria. Outcome measures included: Fatigue Severity Scale, dynamometry, 5 Sit-to-Stand Test, unsupported upper-limb exercise, Euroqol-5 dimensions 5 levels.
Research results
Fatigue severity was higher in the high-risk group at discharge. Upper and lower limb exercise capacity presented poorer results in the high-risk group at discharge. Self-perceived health status also presented significant differences between groups. One month after hospitalization, all differences remained.
Research conclusions
High-risk patients present a poor recovery at discharge and 1 mo after hospitalization. More fatigue and a poorer exercise capacity were found in this group. Both groups undergoing lung resection did not reach control group levels even 1 mo after hospitalization.
Research perspectives
The approach of lung cancer patients should be different depending on the risk profile. Future studies are needed to research the differences between high and low-risk patients in a longer term. Future studies should include objective measures to identify these differences.
