Wang MK, Yu XL, Zhou LY, Si HM, Hui JF, Yang JS. Potential role of vitamin D in patients with diabetes, dyslipidaemia, and COVID-19. World J Crit Care Med 2022; 11(2): 112-114 [PMID: 35433313 DOI: 10.5492/wjccm.v11.i2.112]
Corresponding Author of This Article
Ji-Shun Yang, MD, PhD, Director, Medical Care Center, Naval Medical Center of PLA, Naval Medical University, No. 338 Huaihai West Road, Shanghai 200052, China. jasunyang@foxmail.com
Research Domain of This Article
Nutrition & Dietetics
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Ming-Ke Wang, Xue-Lu Yu, Li-Yun Zhou, Hong-Mei Si, Ju-Fen Hui, Department of Disease Control and Prevention, Naval Medical Center of PLA, Naval Medical University, Shanghai 200052, China
Ji-Shun Yang, Medical Care Center, Naval Medical Center of PLA, Naval Medical University, Shanghai 200052, China
Author contributions: Wang MK wrote the draft; Yu XL, Zhou LY, Si HM, and Hui JF collected the literature; Wang MK and Yang JS conceptualized the article and revised the manuscript; all authors have read and approved the final manuscript.
Supported byMajor Construction Program of Military Key Disciplines during the 13th Five-Year Plan Period, No. 2020SZ21-15.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ji-Shun Yang, MD, PhD, Director, Medical Care Center, Naval Medical Center of PLA, Naval Medical University, No. 338 Huaihai West Road, Shanghai 200052, China. jasunyang@foxmail.com
Received: October 17, 2021 Peer-review started: October 17, 2021 First decision: December 16, 2021 Revised: December 22, 2021 Accepted: February 15, 2022 Article in press: February 15, 2022 Published online: March 9, 2022
Abstract
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 has become a worldwide public health crisis. Studies have demonstrated that diabetes and dyslipidaemia are common comorbidities and could be high-risk factors for severe COVID-19. Vitamin D, a group of fat-soluble compounds responsible for intestinal absorption of calcium, magnesium, and phosphate, has been widely used as a dietary supplement for the prevention and treatment of numerous diseases, including infectious and non-infectious diseases, due to its high cost-effectiveness; safety; tolerability; and anti-thrombotic, anti-inflammatory, antiviral, and immunomodulatory properties. In this letter to the editor, we mainly discuss the potential role of vitamin D in patients with diabetes, dyslipidaemia, and COVID-19.
Core Tip: Diabetes and dyslipidaemia are common comorbidities in patients with coronavirus disease 2019 (COVID-19), and these comorbidities are often associated with worse clinical outcome. In this letter to the editor, we hypothesize that vitamin D may be a prognostic factor and could be a promising preventive measure and treatment for patients with diabetes, dyslipidaemia, and COVID-19.
