Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Epigenomic revolution in autoimmune diseases
Christelle Le Dantec, Yves Renaudineau, INSERM ESPRI, ERI29/EA2216, SFR ScInBioS, LabEx IGO “Immunotherapy Graft Oncology”, Innovative Medicines Initiative PRECISESADS, Réseau épigénétique et réseau canaux ioniques du Cancéropole Grand Ouest, European University of Brittany, F29609 Brest, France
Wesley H Brooks, Department of Chemistry, University of South Florida, Tampa, FL 33620, United States
Yves Renaudineau, Laboratory of Immunology and Immunotherapy, Brest University Medical School Hospital, F29609 Brest, France
Author contributions: All authors have written and contributed to this editorial.
Supported by The “Région Bretagne”, the “Association Française Gougerot-Sjögren et des Syndromes Secs”; by the “Institut Français pour la Recherche Odontologique”; and by the Innovative Medicines Initiative Joint Undertaking under grant agreement n°115565, resources of which are composed of financial contribution from the European Union’s Seventh Framework Programme (FP7/2007-2013) and EFPIA companies’ in-kind contribution.
Conflict-of-interest statement: None.
Open-Access: This article is an open-access article, which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Yves Renaudineau, Professor, Laboratory of Immunology and Immunotherapy, Brest University Medical School Hospital, BP824, F29609 Brest, France. yves.renaudineau@univ-brest.fr
Telephone: +33-2-98223384 Fax: +33-2-98223847
Received: February 23, 2015
Peer-review started: February 25, 2015
First decision: March 20, 2015
Revised: April 22, 2015
Accepted: May 5, 2015
Article in press: May 6, 2015
Published online: July 27, 2015
Processing time: 161 Days and 18.1 Hours
Peer-review started: February 25, 2015
First decision: March 20, 2015
Revised: April 22, 2015
Accepted: May 5, 2015
Article in press: May 6, 2015
Published online: July 27, 2015
Processing time: 161 Days and 18.1 Hours
Core Tip
Core tip: The present editorial focuses on recent progress made in elucidating the relationship between environmental factors, epigenetics, genetics and the pathogenesis of autoimmune diseases (AID). Because of their primary function, epigenetic mechanisms offer potential advantages in terms of prevention, diagnosis, and treatment of complicated diseases such as AID.