Copyright
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Challenges to associate early onset epilepsy with COVID-19 autoimmune encephalitis: A case report
Salma Zouari Mallouli, Olfa Jallouli, Wafa Bouchaala, Sihem Ben Nsir, Fatma Kamoun Feki, Chahnez Charfi Triki, Department of Child Neurology, Hedi Chaker Sfax University Hospital and Research Laboratory LR19ES15-University of Sfax, Tunisia, Sfax 3029, Tunisia
Author contributions: Zouari Mallouli S contributed to manuscript writing and editing, and bibliography; Jallouli O, Bouchaala W, Ben Nsir S contributed to bibliography; Kamoun Feki F, Charfi Triki C contributed to editing and supervision; all authors have read and approved the final manuscript.
Informed consent statement: The patients' legal guardian provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Salma Zouari Mallouli, Doctor, Medical Assistant, Department of Child Neurology, Hedi Chaker Sfax University Hospital and Research Laboratory LR19ES15-University of Sfax, El Ain Street Km 0.5, 3029 Sfax, Tunisia. mallouli.salma26@gmail.com
Received: December 11, 2022
Peer-review started: December 11, 2022
First decision: January 3, 2023
Revised: January 14, 2023
Accepted: February 2, 2023
Article in press: February 2, 2023
Published online: May 31, 2023
Peer-review started: December 11, 2022
First decision: January 3, 2023
Revised: January 14, 2023
Accepted: February 2, 2023
Article in press: February 2, 2023
Published online: May 31, 2023
Core Tip
Core Tip: Overlapping epileptic syndromes and etiologies in infancy constitute a real challenge to the diagnostic and therapeutic approach to autoimmune epilepsy related to post-coronavirus disease 2019 (COVID-19) autoimmune encephalitis (AIE). Indeed, epileptic seizures could entail the onset of seronegative form of post-COVID-19 AIE. Adequate seizure management and control might be hampered by potential misdiagnosis. Defining clinical and paraclinical biomarkers of seronegative form of post-COVID-19 AIE would enable early diagnosis and management, and better prognosis.