Retrospective Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Urol. Mar 24, 2016; 5(1): 53-59
Published online Mar 24, 2016. doi: 10.5410/wjcu.v5.i1.53
Perioperative outcomes and survival of radical cystectomy as a function of body mass index
Bethany K Burge, Robert H Blackwell, Andrew Wilson, Robert C Flanigan, Gopal N Gupta, Marcus L Quek
Bethany K Burge, Robert H Blackwell, Robert C Flanigan, Gopal N Gupta, Marcus L Quek, Department of Urology, Loyola University Medical Center, Maywood, IL 60153, United States
Andrew Wilson, Stritch School of Medicine, Loyola University, Maywood, IL 60153, United States
Author contributions: Burge BK conceived of the study, carried out data acquisition and analysis, and helped to draft the final manuscript; Blackwell RH performed statistical analysis and helped to draft the final manuscript; Wilson A participated in data acquisition and initial drafting of the manuscript; Flanigan RC, Gupta GN, and Quek ML helped with data acquisition and carried out critical revision of the manuscript; all authors read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Loyola University Medical Center Institutional Review Board.
Informed consent statement: This is a retrospective study of a chart review nature and is therefore exempt from informed consent.
Conflict-of-interest statement: The authors have no conflicts of interest to report.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at Bethany.burge@luhs.org. This study was exempt from informed consent given its retrospective, chart review nature. The presented data are anonymized and risk of identification if low.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Bethany K Burge, MD, Department of Urology, Loyola University Medical Center, 2160 S. First Avenue, Fahey Center, Room 261, Maywood, IL 60153, United States. bethany.burge@luhs.org
Telephone: +1-217-7415054 Fax: +1-708-2161699
Received: August 29, 2015
Peer-review started: August 31, 2015
First decision: October 8, 2015
Revised: October 30, 2015
Accepted: February 14, 2016
Article in press: February 16, 2016
Published online: March 24, 2016
Core Tip

Core tip: As obesity rates increase, more obese patients will require radical cystectomy for muscle invasive bladder cancer. Anecdotally, obesity increases the technical difficulty of an operation. Literature regarding outcomes of obese patients undergoing radical cystectomy is limited. This study shows obese patients do better than their non-obese counterparts in terms of perioperative outcomes and overall and disease specific survival. However, we found that underweight patients have a significantly decreased overall and disease specific survival compared with obese and patients.