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Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Urol. Mar 24, 2015; 4(1): 21-26
Published online Mar 24, 2015. doi: 10.5410/wjcu.v4.i1.21
Role of transperineal template biopsy in prostate cancer
Guzanfar Ali Choudry, Mohammed Hidayathullah Khan, Tahir Qayyum
Guzanfar Ali Choudry, Mohammed Hidayathullah Khan, Tahir Qayyum, Department of Urology, Dumfries Royal Infirmary, DG1 4AP Dumfries, United Kingdom
Author contributions: Choudry GA and Khan MH were involved in the writing of the manuscript; Qayyum T was involved in the editing of the manuscript and the literature search.
Conflict-of-interest: There is no conflict to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Tahir Qayyum, MBChB, MRCS, PhD, Department of Urology, Dumfries Royal Infirmary, Bankend Road, DG1 4AP Dumfries, United Kingdom. tahir1@doctors.org.uk
Telephone: +44-1387-246246 Fax: +44-1387-246246
Received: May 23, 2014
Peer-review started: May 23, 2014
First decision: July 18, 2014
Revised: January 12, 2015
Accepted: February 4, 2015
Article in press: February 9, 2015
Published online: March 24, 2015
Processing time: 306 Days and 6.5 Hours
Abstract

Prostate cancer is the most common neoplasm diagnosed in men. Whilst treatment modalities have progressed, diagnostic investigations in terms of biopsy methods have been assessed but there is no consensus of when the different diagnostic methods in terms of transrectal ultrasound (TRUS) or transperineal template (TPT) should be utilised. TPT biopsy has a higher diagnostic yield than TRUS in those with a primary biopsy, in those with previous negative biopsies with TRUS as well as those undergoing saturation biopsies. Despite the increased likelihood of diagnosing cancer with TPT than TRUS this maybe secondary to the increased number of biopsies being utilised. However there is no consensus regarding the ideal number of biopsies that should be utilised with TPT. Furthermore it is felt that the increased number of biopsies utilised with TPT is associated the higher complication rates with TPT. The role of TPT biopsy is recognised in those with previous negative biopsies with transrectal ultrasound but further work is required regarding the ideal number of biopsies. Furthermore, it is felt that TPT biopsy may have a role in primary biopsy.

Keywords: Transrectal prostate biopsy; Transperineal prostate biopsy; Prostate biopsy

Core tip: Transperineal template biopsies are utilised in prostate cancer at an increasing rate instead of transrectal biopsies, yet there is no consensus on how this investigation should be utilised. Here we assess when this method of prostate biopsy is utilised, the number of biopsies that are taken and the method of transperineal template biopsy as well the likelihood of the increase in accuracy in diagnosing prostate cancer.