Retrospective Cohort Study
Copyright ©The Author(s) 2023.
World J Clin Pediatr. Mar 9, 2023; 12(2): 45-56
Published online Mar 9, 2023. doi: 10.5409/wjcp.v12.i2.45
Table 1 Demographic characteristics of survey respondents
Parameters
Parents of IBD patients (n = 51)
Parents of JIA patients (n = 81)
Parents of HC (n = 58)
P value
Patients characteristics
Age of inclusion in the study, years, Me (25%; 75%)13.6 (2.7; 17.0)7.8 (2.0; 18.0)11.3 (3.0; 17.0)0.00006
Gender, females, n (%)24 (47)43 (54) 28 (49)0.0000001
The onset of the disease, years, Me (25%; 75%)10.9 (1.0; 17.0)4.7 (0.8; 16.0)NA0.0000001
Parental status
Gender of representative, females, n (%)49 (96.1)71 (88.2)57 (98.3)0.022
Education level, n (%) -secondary school -higher education -academic degree18 (36) 33 (64) 0 (0)11 (13.6) 66 (81.5) 3 (4.9)13 (22.4) 45 (77.6) 0 (0)0.019
Level of employment, n (%) -working -self-employed -unemployed -receiving welfare support32 (62.7) 5 (9.8) 8 (15.7) 6 (11.8)48 (59) 8 (9.9) 12 (14.8) 13 (16,3)37 (65) 11(18.5) 9 (16.5) 0 (0)> 0.050
Family status, n (%) - Married - Divorced - Widow/widower - Single parent 43 (85.2) 4 (8.6) 1 (1.2) 2 (5)66 (80.4) 9 (11.8) 3 (3.9) 3 (3.9)46 (79.3) 11 (19.0) 1 (1.7) 0 (0)0.327
Table 2 Vaccine coverage of survey respondents
Parameters
Parents of IBD patients (n = 51)
Parents of JIA patients (n = 81)
Parents of HC (n = 58)
P value
Vaccine status
Completed vaccination according to the national calendar, n (%)42 (82.3)65 (79.9)52 (91.4)0.320
Temporary medical contraindications for vaccination (postponed vaccination), n (%)9 (17.6) 14 (17.3)2 (3.4)0.000001
Refused to be vaccinated, n (%)0 (0)2 (2.5)3 (5.2)0.00001
Vaccine-associated reactions: No reaction Fever Injection site reactions38 (74.5) 11 (21.6) 2 (3.9)41 (50.6) 27 (33.3) 13 (16.1)31 (53.5) 14 (24.1) 13 (22.4)0.020
Continued vaccination after diagnosis, n (%)5 (10.9) 6 (7.4)NA0.505
Had an opportunity to discuss vaccinations with the attending physician, n (%) 16 (32)23 (28.4)NA0.716
Control of anti-vaccine antibodies before immunosuppressive treatment, n (%)22 (43.2)24 (29.6)NA0.147
Factors encouraged vaccination, n (%) - Personal beliefs - Doctor's advice - Internet / Media - Parents' forums - Others10 (20) 42 (84) 2 (4) 2 (4) 2 (4)25 (30.8) 56 (69.1) 8 (9.9) 9.9 (12.3) 5 (6.4)40 (70.9) 19 (34.5) 7 (12.7) 1 (1.8) 6 (10.9)0.010
Additional vaccines, n (%), against - tick-borne encephalitis - influenza - meningococcus - pneumococcus - varicella8 (9.8) 6 (11.7) 8 (16.0) 29 (56.8) 6 (12.7)3 (3.7) 9 (11.1) 8 (9.8) 23 (29.4) 7 (6,2)8 (14.5) 20 (35.1) 21 (36.8) 27 (48.9) 17 (30.2)0.003 0.002 0.0000001 0.000004 0.000002