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World J Clin Pediatr. Jun 9, 2025; 14(2): 101080
Published online Jun 9, 2025. doi: 10.5409/wjcp.v14.i2.101080
They will be famous: Multipotent stem cells in breast milk
Gavino Faa, Giuseppina Pichiri, Pierpaolo Coni, Angelica Dessì, Matteo Fraschini, Vassilios Fanos
Gavino Faa, Giuseppina Pichiri, Pierpaolo Coni, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari 09100, Sardegna, Italy
Angelica Dessì, Department of Surgical Sciences, University of Cagliari, Cagliari 09100, Sardegna, Italy
Matteo Fraschini, Department of Ingegneria Elettrica ed Elettronica, University of Cagliari, Cagliari 09100, Sardegna, Italy
Vassilios Fanos, Department of Surgical Sciences, AOU and University of Cagliari, Neonatal Intensive Care Unit, Monserrato 09042, Italy
Author contributions: Faa G revised the literature; Faa G and Fanos V wrote the manuscript; Pichiri G, Coni P, Dessì A, Fraschini M, and Fanos V revised the manuscript; Fanos V had the original idea for this manuscript; and all authors have read and agreed to the published version of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Angelica Dessì, MD, Associate Professor, Department of Surgical Sciences, University of Cagliari, SS 554 Km 4.5, 09042 Monserrato, Cagliari 09100, Sardegna, Italy. angelicadessi@unica.it
Received: September 3, 2024
Revised: January 20, 2025
Accepted: February 12, 2025
Published online: June 9, 2025
Processing time: 195 Days and 14.5 Hours
Core Tip

Core Tip: The presence in the breast milk of a huge number of stem/progenitor cells, able to differentiate into so many different cell types, and their availability at a very low cost without the necessity of obtain complex permissions for their use, has induced in recent years multiple authors to consider the use of maternal milk stem cells in clinical practice. The possible fields of application of milk stem cells are so numerous, including all fields of regenerative medicine.