Copyright
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. Jun 9, 2024; 13(2): 90499
Published online Jun 9, 2024. doi: 10.5409/wjcp.v13.i2.90499
Published online Jun 9, 2024. doi: 10.5409/wjcp.v13.i2.90499
Gut microbiota in preterm infants receiving breast milk or mixed feeding
Sandra Gabriela Sánchez-González, Bárbara Gabriela Cárdenas-del-Castillo, Isaías Rodríguez-Balderrama, Consuelo Treviño-Garza, Gerardo C Palacios-Saucedo, Anthony Gutiérrez-Rodríguez, Manuel Enrique de-la-O-Cavazos, Department of Pediatrics, Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey 64460, Nuevo León, México
Elvira Garza-González, Departamento de Bioquímica y Medicina Molecular, Universidad Autónoma de Nuevo León, Monterrey 64460, Nuevo León, México
Gerardo R Padilla-Rivas, Department of Biochemistry and Molecular Medicine, Universidad Autónoma de Nuevo León, Monterrey 64460, Nuevo León, México
Fernando Félix Montes-Tapia, Department of Pediatric Surgery, Hospital Universitario "Dr. José Eleuterio González", Monterrey 64460, Nuevo León, México
Author contributions: Sánchez-González SG designed the study, participated in the acquisition, analysis, and interpretation of the data, drafted the initial manuscript and gave final approval of the version of the article; Cárdenas-del-Castillo BG and Garza-González E made substantial contributions to conception and design of the study, analysis and interpretation of data, drafted the article and made critical revisions; Padilla-Rivas GR and Palacios-Saucedo GC participated in the analysis and interpretation of the data, drafted the initial manuscript and revised the article critically; Rodríguez- Balderrama I, Treviño-Garza C, Montes-Tapia FF and Gutiérrez-Rodríguez A made substantial contributions to conception of the study, interpretation of the data, revised the article critically for important intellectual content and gave final approval of the version of the article; de-la-O-Cavazos ME was the guarantor and designed the study, revised the article critically for important intellectual content and gave final approval of the version of the article.
Institutional review board statement: The study was reviewed and approved by the Ethics and Research Committee of the School of Medicine, Universidad Autónoma de Nuevo León.
Informed consent statement: Written informed consent was obtained from the parents (legal guardians) of all newborns prior to study enrollment.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: No additional data are available.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sandra Gabriela Sánchez-González, MD, Master's Student, Pediatrics, Hospital Universitario "Dr. José Eleuterio González", Ave. Francisco I. Madero y Gonzalitos S/N Col. Mitras Centro, Monterrey 64460, Nuevo León, México.
Received: December 5, 2023
Revised: March 27, 2024
Accepted: April 17, 2024
Published online: June 9, 2024
Processing time: 184 Days and 14.8 Hours
Revised: March 27, 2024
Accepted: April 17, 2024
Published online: June 9, 2024
Processing time: 184 Days and 14.8 Hours
Core Tip
Core Tip: Gut microbiota in very low-weight preterm infants is characterized by delayed colonization and decreased bacterial species which can lead to complications. In this study, we analyzed it using 16S rRNA gene sequencing in 40 hispanic infants classified into two groups: those receiving breast milk (BM) and those with mixed feeding. A decrease in the counts of Alpha and Betaproteobacteria, with higher counts of bifidobacteria, Bacteroidetes, and Clostridium were observed in the BM group. This study contributes to the literature on the structure of the gut microbial of preterm infants.