Letter to the Editor
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. Mar 9, 2024; 13(1): 89619
Published online Mar 9, 2024. doi: 10.5409/wjcp.v13.i1.89619
Pressure pain sensitivity: A new stress measure in children and adolescents with type 1 diabetes?
Annemarie Cecilie Grauslund, Emilie Bundgaard Lindkvist, Steffen Ullitz Thorsen, Søren Ballegaard, Jens Faber, Jannet Svensson, Anna Korsgaard Berg
Annemarie Cecilie Grauslund, Steffen Ullitz Thorsen, Jannet Svensson, Anna Korsgaard Berg, Department of Pediatrics, Herlev and Gentofte Hospital, Herlev 2730, Denmark
Emilie Bundgaard Lindkvist, Jannet Svensson, Anna Korsgaard Berg, Copenhagen University Hospital, Steno Diabetes Center Copenhagen, Herlev 2730, Denmark
Steffen Ullitz Thorsen, Department of Clinical Immunology, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark
Søren Ballegaard, Jens Faber, Department of Endocrinology, Herlev and Gentofte Hospital, Herlev 2730, Denmark
Jannet Svensson, Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark
Author contributions: Grauslund AC, Ballegaard S, Faber J, Thorsen SU, Svensson J and Berg AK designed the research; Grauslund AC, Svensson J and Berg AK did the clinical visits and investigations; Grauslund AC and Berg AK analyzed the data; Grauslund AC prepared the first original draft; Ballegaard S validated the technique for measurement of PPS; Lindkvist EB helped with analytical tools; Svensson J, Thorsen SU and Berg AK supervised the first author; Lindkvist EB, Ballegaard S, Faber J, Thorsen SU, Svensson J and Berg AK reviewed and edited the manuscript. All authors have read and approved the final manuscript.
Supported by Aase and Ejnar Danielsens Grant; Research grant from the Danish Diabetes Academy, No. NNF17SA0031406; and Research Program from Medtronic.
Conflict-of-interest statement: Grauslund AC: No conflicts of interest; Lindkvist EB: No conflicts of interest; Thorsen SU: No conflicts of interest; Ballegaard S: Invented the instrument used to measure PPS (Ullmeter, patent numbers: PA 2004-00349; PA 2004-00550) and is a shareholder of the firm that owns the PPS instrument (UllMeter A/S). In order to avoid bias, he was not involved in patient contact, collection of data or statistical analysis; Faber J: No conflicts of interest; Svensson J: No conflicts of interest; Berg AK: No conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Anna Korsgaard Berg, MD, PhD, Copenhagen University Hospital, Steno Diabetes Center Copenhagen, Borgmester Ib Juuls Vej 83, Herlev 2730, Denmark. anna.korsgaard.berg@regionh.dk
Received: November 7, 2023
Peer-review started: November 7, 2023
First decision: December 7, 2023
Revised: January 3, 2024
Accepted: January 29, 2024
Article in press: January 29, 2024
Published online: March 9, 2024
Processing time: 120 Days and 17.3 Hours
Core Tip

Core Tip: The aim of present study was to examine whether pressure pain sensitivity (PPS) in children and adolescents associates with other stress measures and determine if it can be used as a clinical tool in this population. Our study revealed some unexpected discrepancies examining PPS in a pediatric population with type 1 diabetes, highlighting the need for more research to validate if PPS is a clinically useful measure in children.